valproic acid has been researched along with Hypomenorrhea in 20 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The long-term effects of valproic acid (VPA) on reproductive endocrine functions in women with epilepsy (WWE) were studied." | 7.75 | Long-term effects of valproic acid on reproductive endocrine functions in Turkish women with epilepsy. ( Dogan, EA; Genc, BO; Genc, E; Gorkemli, H; Ozdemir, S, 2009) |
| "To investigate the development of reproductive endocrine changes in Indian women with epilepsy initiating on either Valproate (VPA) or Lamotrigine (LTG) monotherapy." | 5.27 | Evaluate the effects of antiepileptic drugs on reproductive endocrine system in newly diagnosed female epileptic patients receiving either Valproate or Lamotrigine monotherapy: A prospective study. ( Sadhotra, A; Sidhu, HS; Srinivasa, R, 2018) |
| "Twenty-two female outpatients with a DSM-IV diagnosis of bipolar disorder who were between the ages of 18 and 45 years (inclusive) and who were taking lithium and/or divalproex (10, divalproex monotherapy; 10, lithium monotherapy; 2, divalproex/lithium combination therapy) were evaluated." | 5.09 | Medication status and polycystic ovary syndrome in women with bipolar disorder: a preliminary report. ( Altshuler, LL; Burt, VK; Gudeman, D; Hendrick, V; Korenman, S; Rasgon, NL; Tanavoli, S, 2000) |
| "The long-term effects of valproic acid (VPA) on reproductive endocrine functions in women with epilepsy (WWE) were studied." | 3.75 | Long-term effects of valproic acid on reproductive endocrine functions in Turkish women with epilepsy. ( Dogan, EA; Genc, BO; Genc, E; Gorkemli, H; Ozdemir, S, 2009) |
| "Cyclical menstrual psychosis is an uncommon, generally a self-limiting mental illness that occurs only in females." | 2.58 | An Interesting Presentation About Cyclical Menstrual Psychosis with an Updated Review of Literature. ( Birur, B; Cohen, AW; Nagaraja, S; Thippaiah, SM, 2018) |
| "A possible role of the seizure disorder or, alternatively, of the use of antiepileptic drugs (AEDs) has been suggested as the pathogenic mechanism." | 1.31 | Characterization of reproductive endocrine disorders in women with epilepsy. ( Bilo, L; Di Carlo, C; Meo, R; Nappi, C; Striano, S; Valentino, R, 2001) |
| "Oligomenorrhea occurred in 16 patients, polymenorrhea in 2." | 1.30 | Menstrual cycle and ovary alterations in women with epilepsy on antiepileptic therapy. ( Copello, F; Deagatone, C; Ferrari, E; Galimberti, CA; Gazzerro, E; Gianelli, MV; Magri, F; Manni, R; Murialdo, G; Polleri, A; Rollero, A; Sampaolo, P; Tartara, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 13 (65.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sidhu, HS | 1 |
| Srinivasa, R | 1 |
| Sadhotra, A | 1 |
| Thippaiah, SM | 1 |
| Nagaraja, S | 1 |
| Birur, B | 1 |
| Cohen, AW | 1 |
| Reynolds-May, MF | 1 |
| Kenna, HA | 1 |
| Marsh, W | 1 |
| Stemmle, PG | 1 |
| Wang, P | 1 |
| Ketter, TA | 1 |
| Rasgon, NL | 3 |
| Zhang, L | 1 |
| Li, H | 1 |
| Li, S | 1 |
| Zou, X | 1 |
| Gorkemli, H | 1 |
| Genc, BO | 1 |
| Dogan, EA | 1 |
| Genc, E | 1 |
| Ozdemir, S | 1 |
| Krępuła, K | 1 |
| Bidzińska-Speichert, B | 1 |
| Lenarcik, A | 1 |
| Tworowska-Bardzińska, U | 1 |
| Akdeniz, F | 1 |
| Taneli, F | 1 |
| Noyan, A | 1 |
| Yüncü, Z | 1 |
| Vahip, S | 1 |
| Meo, R | 2 |
| Bilo, L | 2 |
| Altshuler, LL | 2 |
| Fairbanks, L | 1 |
| Elman, S | 1 |
| Bitran, J | 1 |
| Labarca, R | 1 |
| Saad, M | 1 |
| Kupka, R | 1 |
| Nolen, WA | 1 |
| Frye, MA | 1 |
| Suppes, T | 1 |
| McElroy, SL | 1 |
| Keck, PE | 1 |
| Leverich, G | 1 |
| Grunze, H | 1 |
| Walden, J | 1 |
| Post, R | 1 |
| Mintz, J | 1 |
| Herzog, AG | 1 |
| Farina, EL | 1 |
| Blum, AS | 1 |
| Prabhakar, S | 1 |
| Sahota, P | 1 |
| Kharbanda, PS | 1 |
| Siali, R | 1 |
| Jain, V | 1 |
| Lal, V | 1 |
| Khurana, D | 1 |
| Isojärvi, JI | 3 |
| Laatikainen, TJ | 1 |
| Pakarinen, AJ | 2 |
| Juntunen, KT | 1 |
| Myllylä, VV | 1 |
| Murialdo, G | 1 |
| Galimberti, CA | 1 |
| Magri, F | 1 |
| Sampaolo, P | 1 |
| Copello, F | 1 |
| Gianelli, MV | 1 |
| Gazzerro, E | 1 |
| Rollero, A | 1 |
| Deagatone, C | 1 |
| Manni, R | 1 |
| Ferrari, E | 1 |
| Polleri, A | 1 |
| Tartara, A | 1 |
| Piontek, CM | 1 |
| Wisner, KL | 1 |
| Gudeman, D | 1 |
| Burt, VK | 1 |
| Tanavoli, S | 1 |
| Hendrick, V | 1 |
| Korenman, S | 1 |
| Tapanainen, JS | 2 |
| Valentino, R | 1 |
| Di Carlo, C | 1 |
| Striano, S | 1 |
| Nappi, C | 1 |
| Stephen, LJ | 1 |
| Kwan, P | 1 |
| Shapiro, D | 1 |
| Dominiczak, M | 1 |
| Brodie, MJ | 1 |
| Taubøll, E | 1 |
| van Parys, J | 1 |
| Rättyä, J | 1 |
| Harbo, HF | 1 |
| Dale, PO | 1 |
| Fauser, BC | 1 |
| Gjerstad, L | 1 |
| Koivunen, R | 1 |
| Knip, M | 1 |
| O'Donovan, C | 1 |
| Kusumakar, V | 1 |
| Graves, GR | 1 |
| Bird, DC | 1 |
4 reviews available for valproic acid and Hypomenorrhea
| Article | Year |
|---|---|
An Interesting Presentation About Cyclical Menstrual Psychosis with an Updated Review of Literature.
Topics: Adult; Female; Humans; Menstruation Disturbances; Psychotic Disorders; Risperidone; Tranquilizing Ag | 2018 |
Reproductive and metabolic abnormalities in women taking valproate for bipolar disorder: a meta-analysis.
Topics: Bipolar Disorder; Female; Humans; Hyperandrogenism; Menstruation Disturbances; Metabolic Diseases; P | 2016 |
Psychiatric disorders related to polycystic ovary syndrome.
Topics: Antimanic Agents; Bipolar Disorder; Depression; Feeding and Eating Disorders; Female; Hirsutism; Hor | 2012 |
Polycystic ovary syndrome and epilepsy: a review of the evidence.
Topics: Adolescent; Adult; Anticonvulsants; Clinical Trials as Topic; Epilepsy; Female; Humans; Menstruation | 2003 |
2 trials available for valproic acid and Hypomenorrhea
| Article | Year |
|---|---|
Evaluate the effects of antiepileptic drugs on reproductive endocrine system in newly diagnosed female epileptic patients receiving either Valproate or Lamotrigine monotherapy: A prospective study.
Topics: Adolescent; Adult; Anticonvulsants; Endocrine System; Epilepsy; Female; Follow-Up Studies; Hormones; | 2018 |
Medication status and polycystic ovary syndrome in women with bipolar disorder: a preliminary report.
Topics: Adolescent; Adult; Anticonvulsants; Bipolar Disorder; Drug Administration Schedule; Drug Therapy, Co | 2000 |
14 other studies available for valproic acid and Hypomenorrhea
| Article | Year |
|---|---|
Evaluation of reproductive function in women treated for bipolar disorder compared to healthy controls.
Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Menstruation Disturbances | 2014 |
Long-term effects of valproic acid on reproductive endocrine functions in Turkish women with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Hype | 2009 |
Valproate-associated reproductive and metabolic abnormalities: are epileptic women at greater risk than bipolar women?
Topics: Adult; Antimanic Agents; Bipolar Disorder; Cross-Sectional Studies; Endocrine System; Epilepsy; Fema | 2003 |
Reproductive function and risk for PCOS in women treated for bipolar disorder.
Topics: Adolescent; Adult; Antimanic Agents; Bipolar Disorder; Endocrine System Diseases; Female; Humans; Me | 2005 |
Serum valproate levels with oral contraceptive use.
Topics: Adult; Anticonvulsants; Comorbidity; Contraceptives, Oral, Combined; Drug Combinations; Drug Interac | 2005 |
Sodium valproate, hyperandrogenism and altered ovarian function in Indian women with epilepsy: a prospective study.
Topics: Body Mass Index; Epilepsy; Female; Follow-Up Studies; Hirsutism; Humans; Hyperandrogenism; Indians, | 2007 |
Polycystic ovaries and hyperandrogenism in women taking valproate for epilepsy.
Topics: Adolescent; Adult; Analysis of Variance; Carbamazepine; Cross-Sectional Studies; Epilepsies, Partial | 1993 |
Menstrual cycle and ovary alterations in women with epilepsy on antiepileptic therapy.
Topics: Adolescent; Adult; Anovulation; Anticonvulsants; Corpus Luteum; Epilepsy; Female; Humans; Menstruati | 1997 |
Appropriate clinical management of women taking valproate.
Topics: Adult; Age Factors; Anticonvulsants; Body Weight; Epilepsy; Female; Humans; Hyperandrogenism; Insuli | 2000 |
Valproate, hyperandrogenism, and polycystic ovaries: a report of 3 cases.
Topics: Adolescent; Adult; Anticonvulsants; Body Weight; Electroencephalography; Epilepsy; Female; Humans; H | 2000 |
Characterization of reproductive endocrine disorders in women with epilepsy.
Topics: Adolescent; Adult; Amenorrhea; Anticonvulsants; Endocrine System Diseases; Epilepsy; Female; Humans; | 2001 |
Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy.
Topics: Adult; Anticonvulsants; Blood Glucose; Body Mass Index; Comorbidity; Dehydroepiandrosterone; Epileps | 2001 |
Altered ovarian function and cardiovascular risk factors in valproate-treated women.
Topics: Adult; Analysis of Variance; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Case-Control S | 2001 |
Menstrual abnormalities and polycystic ovary syndrome in women taking valproate for bipolar mood disorder.
Topics: Adolescent; Adult; Age Factors; Ambulatory Care; Anticonvulsants; Bipolar Disorder; Female; Health S | 2002 |