Page last updated: 2024-10-26

valproic acid and Hypogonadism

valproic acid has been researched along with Hypogonadism in 5 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Hypogonadism: Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).

Research Excerpts

ExcerptRelevanceReference
"Hypogonadotropic hypogonadism is a rare congenital disorder characterised by the deficiency and the absence of puberty and infertility."1.48Rare cause of manic period trigger in bipolar mood disorder: testosterone replacement. ( Elboga, G; Sayiner, ZA, 2018)
"One hundred seventy-eight men had focal epilepsy (117 of these had temporal lobe epilepsy [TLE]) and 22 idiopathic generalized epilepsy (IGE)."1.32Epilepsy syndrome, focus location, and treatment choice affect testicular function in men with epilepsy. ( Bauer, J; Blumenthal, S; Reuber, M; Stoffel-Wagner, B, 2004)
"Men with epilepsy have reduced fertility, and antiepileptic drugs may affect semen quality."1.32Effect of epilepsy and antiepileptic drugs on male reproductive health. ( Isojärvi, JI; Juntunen, KS; Löfgren, E; Päivänsalo, M; Pakarinen, AJ; Rautakorpi, I; Tuomivaara, L, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elboga, G1
Sayiner, ZA1
Kenna, HA1
Jiang, B1
Rasgon, NL1
Gates, JR1
Bauer, J1
Blumenthal, S1
Reuber, M1
Stoffel-Wagner, B1
Isojärvi, JI1
Löfgren, E1
Juntunen, KS1
Pakarinen, AJ1
Päivänsalo, M1
Rautakorpi, I1
Tuomivaara, L1

Reviews

1 review available for valproic acid and Hypogonadism

ArticleYear
Reproductive and metabolic abnormalities associated with bipolar disorder and its treatment.
    Harvard review of psychiatry, 2009, Volume: 17, Issue:2

    Topics: Bipolar Disorder; Dyslipidemias; Endocrine System Diseases; Female; Humans; Hypogonadism; Hypothalam

2009

Other Studies

4 other studies available for valproic acid and Hypogonadism

ArticleYear
Rare cause of manic period trigger in bipolar mood disorder: testosterone replacement.
    BMJ case reports, 2018, Aug-03, Volume: 2018

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Chorionic Gonadotropin; Hormone Rep

2018
Epilepsy versus antiepileptic drugs and gonadal function in men.
    Neurology, 2004, Jan-27, Volume: 62, Issue:2

    Topics: Androstenedione; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy, Generalized; Humans;

2004
Epilepsy syndrome, focus location, and treatment choice affect testicular function in men with epilepsy.
    Neurology, 2004, Jan-27, Volume: 62, Issue:2

    Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epileps

2004
Effect of epilepsy and antiepileptic drugs on male reproductive health.
    Neurology, 2004, Jan-27, Volume: 62, Issue:2

    Topics: Adult; Androstenedione; Anticonvulsants; Carbamazepine; Dehydroepiandrosterone Sulfate; Epilepsies,

2004