Page last updated: 2024-10-26

valproic acid and Hypesthesia

valproic acid has been researched along with Hypesthesia in 2 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Hypesthesia: Absent or reduced sensitivity to cutaneous stimulation.

Research Excerpts

ExcerptRelevanceReference
"Hypoesthesia is a clinical feature of neuropathic pain."1.39HDAC inhibitors restore C-fibre sensitivity in experimental neuropathic pain model. ( Araki, K; Matsushita, Y; Mukae, T; Omotuyi, Oi; Ueda, H, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsushita, Y1
Araki, K1
Omotuyi, Oi1
Mukae, T1
Ueda, H1
Boyle, NJ1
Clarke, MP1
Figueiredo, F1

Other Studies

2 other studies available for valproic acid and Hypesthesia

ArticleYear
HDAC inhibitors restore C-fibre sensitivity in experimental neuropathic pain model.
    British journal of pharmacology, 2013, Volume: 170, Issue:5

    Topics: Acetylation; Analgesics; Animals; Chromatin Assembly and Disassembly; Disease Models, Animal; Epigen

2013
Reduced corneal sensation and severe dry eyes in a child with fetal valproate syndrome.
    Eye (London, England), 2001, Volume: 15, Issue:Pt 5

    Topics: Anticonvulsants; Corneal Diseases; Female; Humans; Hypesthesia; Infant, Newborn; Pregnancy; Prenatal

2001