valproic acid has been researched along with Hypertension, Portal in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a case of hyperammonaemic coma precipitated by sodium valproate use for symptomatic epilepsy in a patient with unrecognised portosystemic shunt, secondary to earlier alcoholism." | 5.39 | Valproic acid-induced hyperammonaemic coma and unrecognised portosystemic shunt. ( Basilio, C; Carrapatoso, L; Ferreira, F; Nzwalo, H, 2013) |
| "We present a case of hyperammonaemic coma precipitated by sodium valproate use for symptomatic epilepsy in a patient with unrecognised portosystemic shunt, secondary to earlier alcoholism." | 1.39 | Valproic acid-induced hyperammonaemic coma and unrecognised portosystemic shunt. ( Basilio, C; Carrapatoso, L; Ferreira, F; Nzwalo, H, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Izadi Firouzabadi, L | 1 |
| Geer, K | 1 |
| Mead, P | 1 |
| Nzwalo, H | 1 |
| Carrapatoso, L | 1 |
| Ferreira, F | 1 |
| Basilio, C | 1 |
2 other studies available for valproic acid and Hypertension, Portal
| Article | Year |
|---|---|
Severe hyperammonaemic encephalopathy resulting from the overlap between hepatic and valproate encephalopathy.
Topics: Alcoholism; Brain Diseases; Epilepsy; Humans; Hyperammonemia; Hypertension, Portal; Male; Middle Age | 2018 |
Valproic acid-induced hyperammonaemic coma and unrecognised portosystemic shunt.
Topics: Anticonvulsants; Coma; Humans; Hyperammonemia; Hypertension, Portal; Liver Diseases, Alcoholic; Male | 2013 |