Page last updated: 2024-10-26

valproic acid and Hypernatremia

valproic acid has been researched along with Hypernatremia in 5 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Hypernatremia: Excessive amount of sodium in the blood. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"This hypernatremia was due to renal diabetes insipidus stemming from the decades of lithium therapy, with accompanying polydipsia and polyuria, and also to the failure to give enough fluid to the somnolent patient."1.31[Hypernatremia as a rare complication in change from lithium to valproate]. ( Berendes, K; Glass, W; Warmke, C, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Naschitz, JE1
Leibovitz, G1
Berendes, K2
Davison, AS1
Milan, AM1
Roberts, NB1
Lee, WL1
Yang, CC1
Deng, JF1
Chen, YF1
Lin, HD1
Wang, PH1
Glass, W1
Warmke, C1

Other Studies

5 other studies available for valproic acid and Hypernatremia

ArticleYear
Sodium valproate correcting hypernatremia of diabetes insipidus-a fortunate incident.
    QJM : monthly journal of the Association of Physicians, 2018, Nov-01, Volume: 111, Issue:11

    Topics: Adult; Diabetes Insipidus, Neurogenic; Epilepsy; Humans; Hypernatremia; Male; Valproic Acid

2018
[Hypo- and hypernatremia].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:21

    Topics: Anticonvulsants; Antimanic Agents; Carbamazepine; Diabetes Insipidus, Nephrogenic; Humans; Hypernatr

2011
The consequences of valproate overdose.
    Clinical chemistry, 2011, Volume: 57, Issue:9

    Topics: Acid-Base Equilibrium; Acidosis, Lactic; Adult; Anticonvulsants; Carnitine; Drug Overdose; Epilepsy;

2011
A case of severe hyperammonemia and unconsciousness following sodium valproate intoxication.
    Veterinary and human toxicology, 1998, Volume: 40, Issue:6

    Topics: Adolescent; Ammonia; Anion Exchange Resins; Anticonvulsants; Cholestyramine Resin; Drug Overdose; Hu

1998
[Hypernatremia as a rare complication in change from lithium to valproate].
    Der Nervenarzt, 2001, Volume: 72, Issue:7

    Topics: Antimanic Agents; Bipolar Disorder; Diabetes Insipidus, Nephrogenic; Drug Therapy, Combination; Fema

2001