Page last updated: 2024-10-26

valproic acid and Hormone-Dependent Neoplasms

valproic acid has been researched along with Hormone-Dependent Neoplasms in 2 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"Treatment efficacy of breast cancer can be impaired by cell resistance."5.35Valproic acid is a selective antiproliferative agent in estrogen-sensitive breast cancer cells. ( Bertino, S; Boccuzzi, G; Bosco, O; Catalano, MG; Costantino, L; Fortunati, N; Vercellinatto, I, 2008)
"Treatment efficacy of breast cancer can be impaired by cell resistance."1.35Valproic acid is a selective antiproliferative agent in estrogen-sensitive breast cancer cells. ( Bertino, S; Boccuzzi, G; Bosco, O; Catalano, MG; Costantino, L; Fortunati, N; Vercellinatto, I, 2008)
"Valproic acid (VPA) is an established drug in the long-term therapy of seizure disorders."1.33Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo. ( Carducci, M; Chen, CL; Chowdhury, W; Höti, N; Rodriguez, R; Shabbeer, S; Sung, J; Xia, Q, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xia, Q1
Sung, J1
Chowdhury, W1
Chen, CL1
Höti, N1
Shabbeer, S1
Carducci, M1
Rodriguez, R1
Fortunati, N1
Bertino, S1
Costantino, L1
Bosco, O1
Vercellinatto, I1
Catalano, MG1
Boccuzzi, G1

Other Studies

2 other studies available for valproic acid and Hormone-Dependent Neoplasms

ArticleYear
Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo.
    Cancer research, 2006, Jul-15, Volume: 66, Issue:14

    Topics: Acetylation; Animals; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Drug Administration Sc

2006
Valproic acid is a selective antiproliferative agent in estrogen-sensitive breast cancer cells.
    Cancer letters, 2008, Feb-08, Volume: 259, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Breast Neoplasms; Casp

2008