valproic acid has been researched along with Hormone-Dependent Neoplasms in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Excerpt | Relevance | Reference |
---|---|---|
"Treatment efficacy of breast cancer can be impaired by cell resistance." | 5.35 | Valproic acid is a selective antiproliferative agent in estrogen-sensitive breast cancer cells. ( Bertino, S; Boccuzzi, G; Bosco, O; Catalano, MG; Costantino, L; Fortunati, N; Vercellinatto, I, 2008) |
"Treatment efficacy of breast cancer can be impaired by cell resistance." | 1.35 | Valproic acid is a selective antiproliferative agent in estrogen-sensitive breast cancer cells. ( Bertino, S; Boccuzzi, G; Bosco, O; Catalano, MG; Costantino, L; Fortunati, N; Vercellinatto, I, 2008) |
"Valproic acid (VPA) is an established drug in the long-term therapy of seizure disorders." | 1.33 | Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo. ( Carducci, M; Chen, CL; Chowdhury, W; Höti, N; Rodriguez, R; Shabbeer, S; Sung, J; Xia, Q, 2006) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Xia, Q | 1 |
Sung, J | 1 |
Chowdhury, W | 1 |
Chen, CL | 1 |
Höti, N | 1 |
Shabbeer, S | 1 |
Carducci, M | 1 |
Rodriguez, R | 1 |
Fortunati, N | 1 |
Bertino, S | 1 |
Costantino, L | 1 |
Bosco, O | 1 |
Vercellinatto, I | 1 |
Catalano, MG | 1 |
Boccuzzi, G | 1 |
2 other studies available for valproic acid and Hormone-Dependent Neoplasms
Article | Year |
---|---|
Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo.
Topics: Acetylation; Animals; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Drug Administration Sc | 2006 |
Valproic acid is a selective antiproliferative agent in estrogen-sensitive breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Breast Neoplasms; Casp | 2008 |