valproic acid has been researched along with Hirsutism in 7 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Hirsutism: A condition observed in WOMEN and CHILDREN when there is excess coarse body hair of an adult male distribution pattern, such as facial and chest areas. It is the result of elevated ANDROGENS from the OVARIES, the ADRENAL GLANDS, or exogenous sources. The concept does not include HYPERTRICHOSIS, which is an androgen-independent excessive hair growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-two female outpatients with a DSM-IV diagnosis of bipolar disorder who were between the ages of 18 and 45 years (inclusive) and who were taking lithium and/or divalproex (10, divalproex monotherapy; 10, lithium monotherapy; 2, divalproex/lithium combination therapy) were evaluated." | 5.09 | Medication status and polycystic ovary syndrome in women with bipolar disorder: a preliminary report. ( Altshuler, LL; Burt, VK; Gudeman, D; Hendrick, V; Korenman, S; Rasgon, NL; Tanavoli, S, 2000) |
| " Therefore, this multicenter cross-sectional study aimed to evaluate the prevalence of reproductive endocrine dysfunctions in pubertal females with epilepsy receiving VPA, lamotrigine (LTG), or levetiracetam (LEV) monotherapy." | 3.80 | Reproductive endocrine health in pubertal females with epilepsy on antiepileptic drugs: time to screen? ( Agostinelli, S; Baumann, M; Haberlandt, E; Luef, G; Pizzolorusso, A; Prieschl, M; Rauchenzauner, M; Roscia, S; Rostasy, K; Verrotti, A; Wildt, L, 2014) |
| "Weight gain and alopecia were the most common patient-reported CSEs in this study, and weight gain was the most likely cosmetic side effect to result in dosage adjustment or medication discontinuation." | 1.42 | Cosmetic side effects of antiepileptic drugs in adults with epilepsy. ( Buchsbaum, R; Chen, B; Choi, H; Detyniecki, K; Hirsch, LJ; Javed, A; Kato, K; Legge, A; Moeller, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rauchenzauner, M | 1 |
| Roscia, S | 1 |
| Prieschl, M | 1 |
| Wildt, L | 1 |
| Haberlandt, E | 1 |
| Baumann, M | 1 |
| Rostasy, K | 1 |
| Agostinelli, S | 1 |
| Pizzolorusso, A | 1 |
| Luef, G | 1 |
| Verrotti, A | 1 |
| Chen, B | 1 |
| Choi, H | 1 |
| Hirsch, LJ | 1 |
| Moeller, J | 1 |
| Javed, A | 1 |
| Kato, K | 1 |
| Legge, A | 1 |
| Buchsbaum, R | 1 |
| Detyniecki, K | 1 |
| Krępuła, K | 1 |
| Bidzińska-Speichert, B | 1 |
| Lenarcik, A | 1 |
| Tworowska-Bardzińska, U | 1 |
| Akdeniz, F | 1 |
| Taneli, F | 1 |
| Noyan, A | 1 |
| Yüncü, Z | 1 |
| Vahip, S | 1 |
| Joffe, H | 1 |
| Cohen, LS | 1 |
| Suppes, T | 1 |
| Hwang, CH | 1 |
| Molay, F | 1 |
| Adams, JM | 1 |
| Sachs, GS | 1 |
| Hall, JE | 1 |
| Prabhakar, S | 1 |
| Sahota, P | 1 |
| Kharbanda, PS | 1 |
| Siali, R | 1 |
| Jain, V | 1 |
| Lal, V | 1 |
| Khurana, D | 1 |
| Rasgon, NL | 1 |
| Altshuler, LL | 1 |
| Gudeman, D | 1 |
| Burt, VK | 1 |
| Tanavoli, S | 1 |
| Hendrick, V | 1 |
| Korenman, S | 1 |
1 review available for valproic acid and Hirsutism
| Article | Year |
|---|---|
Psychiatric disorders related to polycystic ovary syndrome.
Topics: Antimanic Agents; Bipolar Disorder; Depression; Feeding and Eating Disorders; Female; Hirsutism; Hor | 2012 |
1 trial available for valproic acid and Hirsutism
| Article | Year |
|---|---|
Medication status and polycystic ovary syndrome in women with bipolar disorder: a preliminary report.
Topics: Adolescent; Adult; Anticonvulsants; Bipolar Disorder; Drug Administration Schedule; Drug Therapy, Co | 2000 |
5 other studies available for valproic acid and Hirsutism
| Article | Year |
|---|---|
Reproductive endocrine health in pubertal females with epilepsy on antiepileptic drugs: time to screen?
Topics: Adiposity; Adolescent; Anticonvulsants; Cohort Studies; Cross-Sectional Studies; Drug Evaluation, Pr | 2014 |
Cosmetic side effects of antiepileptic drugs in adults with epilepsy.
Topics: Acne Vulgaris; Adult; Alopecia; Anticonvulsants; Epilepsy; Female; gamma-Aminobutyric Acid; Gingival | 2015 |
Valproate-associated reproductive and metabolic abnormalities: are epileptic women at greater risk than bipolar women?
Topics: Adult; Antimanic Agents; Bipolar Disorder; Cross-Sectional Studies; Endocrine System; Epilepsy; Fema | 2003 |
Longitudinal follow-up of reproductive and metabolic features of valproate-associated polycystic ovarian syndrome features: A preliminary report.
Topics: Adolescent; Adult; Antimanic Agents; Bipolar Disorder; Body Mass Index; Female; Follow-Up Studies; H | 2006 |
Sodium valproate, hyperandrogenism and altered ovarian function in Indian women with epilepsy: a prospective study.
Topics: Body Mass Index; Epilepsy; Female; Follow-Up Studies; Hirsutism; Humans; Hyperandrogenism; Indians, | 2007 |