valproic acid has been researched along with Hip Fractures in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Hip Fractures: Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Reported is a 16-year-old man with intractable epilepsy and an 11-year history of chronic hyponatraemia (126-135 mEq/L) due to valproic acid induced syndrome of inappropriate antidiuresis who sustained low-impact fragility fractures and had evidence of osteopaenia on both X-ray and dual energy X-ray absorptiometry (DEXA)." | 3.91 | Fragility fractures and reversible osteopaenia due to chronic hyponatraemia in an adolescent male. ( Ayus, JC; Moritz, ML; Patel, M, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patel, M | 1 |
| Ayus, JC | 1 |
| Moritz, ML | 1 |
| Pavlakis, SG | 1 |
| Chusid, RL | 1 |
| Roye, DP | 1 |
| Nordli, DR | 1 |
2 other studies available for valproic acid and Hip Fractures
| Article | Year |
|---|---|
Fragility fractures and reversible osteopaenia due to chronic hyponatraemia in an adolescent male.
Topics: Absorptiometry, Photon; Adolescent; Anticonvulsants; Bone Density; Bone Diseases, Metabolic; Epileps | 2019 |
Valproate therapy: predisposition to bone fracture?
Topics: Adolescent; Bone and Bones; Disease Susceptibility; Epilepsy; Female; Femoral Fractures; Foot; Fract | 1998 |