valproic acid has been researched along with Herpes Simplex in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Herpes Simplex: A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A currently studied experimental treatment for gliomas consists of intratumoral injection of oncolytic viruses (OV), such as oncolytic herpes simplex virus type 1 (oHSV)." | 1.39 | STAT3 activation promotes oncolytic HSV1 replication in glioma cells. ( Chiocca, EA; Haseley, A; Kaur, B; Meisen, H; Okemoto, K; Wagner, B, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okemoto, K | 1 |
| Wagner, B | 1 |
| Meisen, H | 1 |
| Haseley, A | 1 |
| Kaur, B | 1 |
| Chiocca, EA | 1 |
1 other study available for valproic acid and Herpes Simplex
| Article | Year |
|---|---|
STAT3 activation promotes oncolytic HSV1 replication in glioma cells.
Topics: Anticonvulsants; Blotting, Western; Brain Neoplasms; Cell Proliferation; Combined Modality Therapy; | 2013 |