valproic acid has been researched along with Hepatitis, Chronic in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Hepatitis, Chronic: INFLAMMATION of the LIVER with ongoing hepatocellular injury for 6 months or more, characterized by NECROSIS of HEPATOCYTES and inflammatory cell (LEUKOCYTES) infiltration. Chronic hepatitis can be caused by viruses, medications, autoimmune diseases, and other unknown factors.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproic acid has been implicated in at least 100 cases of fatal acute liver failure." | 1.28 | Incidental microvesicular steatosis due to valproic acid anticonvulsant therapy. ( Bacon, BR; Gholson, CF; Gonzalez, E; Netchvolodoff, CV; Ray, M; Scott, DA, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scott, DA | 1 |
| Gholson, CF | 1 |
| Netchvolodoff, CV | 1 |
| Ray, M | 1 |
| Gonzalez, E | 1 |
| Bacon, BR | 1 |
1 other study available for valproic acid and Hepatitis, Chronic
| Article | Year |
|---|---|
Incidental microvesicular steatosis due to valproic acid anticonvulsant therapy.
Topics: Adult; Fatty Liver; Hepatitis C; Hepatitis, Chronic; Humans; Male; Seizures; Valproic Acid | 1991 |