valproic acid has been researched along with Hepatic Porphyria in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a patient with focal epilepsy and latent hereditary coproporphyria who had exacerbation of clinical symptoms of porphyria under treatment with valproate and primidone and was then treated with levetiracetam without exacerbation of clinically latent porphyria." | 5.32 | Levetiracetam in focal epilepsy and hepatic porphyria: a case report. ( Meencke, HJ; Paul, F, 2004) |
| "We report a patient with focal epilepsy and latent hereditary coproporphyria who had exacerbation of clinical symptoms of porphyria under treatment with valproate and primidone and was then treated with levetiracetam without exacerbation of clinically latent porphyria." | 1.32 | Levetiracetam in focal epilepsy and hepatic porphyria: a case report. ( Meencke, HJ; Paul, F, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, CD | 1 |
| Van Horn, CG | 1 |
| Wan, M | 1 |
| Bishop, C | 1 |
| Bonkovsky, HL | 1 |
| Paul, F | 1 |
| Meencke, HJ | 1 |
2 other studies available for valproic acid and Hepatic Porphyria
| Article | Year |
|---|---|
Assessment of porphyrogenicity of drugs and chemicals in selected hepatic cell culture models through a fluorescence-based screening assay.
Topics: Cell Culture Techniques; Heme; Hepatocytes; Humans; Liver; Norgestrel; Phenobarbital; Phenytoin; Por | 2022 |
Levetiracetam in focal epilepsy and hepatic porphyria: a case report.
Topics: Acute Disease; Adult; Anticonvulsants; Comorbidity; Epilepsies, Partial; Female; Humans; Levetiracet | 2004 |