valproic acid has been researched along with Hemolysis in 7 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " With this new assay, high concentrations of bilirubin (unconjugated 30 mg/dL and conjugated 30 mg/dL) and gross hemolysis (4+, hemoglobin: 1,500 mg/dL) have no effect on measurements of valproic acid concentration." | 7.73 | Analytical performance evaluation of a new turbidimetric immunoassay for valproic acid on the ADVIA 1650 analyzer: effect of gross hemolysis and high bilirubin. ( Dasgupta, A; Datta, P, 2005) |
| " Life-threatening valproic acid toxicity is an indication for coated charcoal hemoperfusion usually accomplished without complications, but we report a case of acute severe intravascular hemolysis during the time of hemoperfusion with coated charcoal column." | 7.73 | Acute hemolysis with acute renal failure in a patient with valproic acid poisoning treated with charcoal hemoperfusion. ( Haqqie, SS; McGoldrick, MD; Rahman, MH, 2006) |
| " With this new assay, high concentrations of bilirubin (unconjugated 30 mg/dL and conjugated 30 mg/dL) and gross hemolysis (4+, hemoglobin: 1,500 mg/dL) have no effect on measurements of valproic acid concentration." | 3.73 | Analytical performance evaluation of a new turbidimetric immunoassay for valproic acid on the ADVIA 1650 analyzer: effect of gross hemolysis and high bilirubin. ( Dasgupta, A; Datta, P, 2005) |
| " Life-threatening valproic acid toxicity is an indication for coated charcoal hemoperfusion usually accomplished without complications, but we report a case of acute severe intravascular hemolysis during the time of hemoperfusion with coated charcoal column." | 3.73 | Acute hemolysis with acute renal failure in a patient with valproic acid poisoning treated with charcoal hemoperfusion. ( Haqqie, SS; McGoldrick, MD; Rahman, MH, 2006) |
| " No interference from hemolysis, hyperbilirubinemia, or aliphatic amino acids was observed." | 3.66 | Evaluation of a new valproic acid enzyme immunoassay and comparison with a capillary gas-chromatographic method. ( Braun, SL; Jacob, K; Knedel, M; Tausch, A; Vogt, W, 1981) |
| "Ketamine itself was apparently without effect as the administration of a second dose of ketamine did not significantly alter the levels of any of the amino acids studied, although GABA levels tended to decrease." | 1.28 | Effects of pharmacological manipulation on neurotransmitter and other amino acid levels in the CSF of the Senegalese baboon Papio papio. ( Lloyd, KG; Naquet, R; Valin, A; Voltz, C, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Datta, P | 1 |
| Dasgupta, A | 1 |
| Rahman, MH | 1 |
| Haqqie, SS | 1 |
| McGoldrick, MD | 1 |
| Hirose, Y | 1 |
| Konda, S | 1 |
| Braun, SL | 1 |
| Tausch, A | 1 |
| Vogt, W | 1 |
| Jacob, K | 1 |
| Knedel, M | 1 |
| Leroux, M | 1 |
| Budnik, D | 1 |
| Hall, K | 1 |
| Irvine-Meek, J | 1 |
| Otten, N | 1 |
| Seshia, S | 1 |
| Klose, PK | 1 |
| Pache, HD | 1 |
| Uhl, HC | 1 |
| Valin, A | 1 |
| Voltz, C | 1 |
| Naquet, R | 1 |
| Lloyd, KG | 1 |
7 other studies available for valproic acid and Hemolysis
| Article | Year |
|---|---|
Analytical performance evaluation of a new turbidimetric immunoassay for valproic acid on the ADVIA 1650 analyzer: effect of gross hemolysis and high bilirubin.
Topics: Anticonvulsants; Bilirubin; Drug Monitoring; Hemolysis; Humans; Immunoassay; Nephelometry and Turbid | 2005 |
Acute hemolysis with acute renal failure in a patient with valproic acid poisoning treated with charcoal hemoperfusion.
Topics: Acute Kidney Injury; Charcoal; Female; Hemolysis; Hemoperfusion; Humans; Middle Aged; Valproic Acid | 2006 |
Depakene-induced intravascular hemolysis and pure red cell aplasia.
Topics: Female; Hemolysis; Humans; Middle Aged; Red-Cell Aplasia, Pure; Valproic Acid | 1984 |
Evaluation of a new valproic acid enzyme immunoassay and comparison with a capillary gas-chromatographic method.
Topics: Amino Acids; Bilirubin; Blood Chemical Analysis; Chromatography, Gas; Evaluation Studies as Topic; H | 1981 |
Comparison of gas-liquid chromatography and EMIT assay for serum valproic acid.
Topics: Bilirubin; Chromatography, Gas; Hemolysis; Heparin; Humans; Hyperlipidemias; Immunoenzyme Techniques | 1981 |
[Disorders of hemostasis caused by dipropylacetate].
Topics: Blood Platelet Disorders; Child; Disseminated Intravascular Coagulation; Epilepsy, Tonic-Clonic; Fem | 1977 |
Effects of pharmacological manipulation on neurotransmitter and other amino acid levels in the CSF of the Senegalese baboon Papio papio.
Topics: Amino Acids; Animals; Diazepam; Dizocilpine Maleate; Electroshock; Hemolysis; Humans; Ketamine; Neur | 1991 |