valproic acid has been researched along with Heart Diseases in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of losartan with sodium valproate in epilepsy may prevent the cognitive and cardiac sequelae of seizures." | 7.91 | Effects of enalapril and losartan alone and in combination with sodium valproate on seizures, memory, and cardiac changes in rats. ( Arava, S; Gupta, YK; Joshi, D; Katyal, J, 2019) |
| "The use of losartan with sodium valproate in epilepsy may prevent the cognitive and cardiac sequelae of seizures." | 3.91 | Effects of enalapril and losartan alone and in combination with sodium valproate on seizures, memory, and cardiac changes in rats. ( Arava, S; Gupta, YK; Joshi, D; Katyal, J, 2019) |
| "Valproic acid (VPA) is an anti-epileptic and mood-stabilizing compound successfully used in the clinics since many decades." | 2.50 | Cardio-hepatic metabolic derangements and valproic acid. ( Longhitano, C; Mazzoccoli, G; Vinciguerra, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joshi, D | 1 |
| Katyal, J | 1 |
| Arava, S | 1 |
| Gupta, YK | 1 |
| Mazzoccoli, G | 1 |
| Longhitano, C | 1 |
| Vinciguerra, M | 1 |
| Bratton, SL | 1 |
| Garden, AL | 1 |
| Bohan, TP | 1 |
| French, JW | 1 |
| Clarke, WR | 1 |
1 review available for valproic acid and Heart Diseases
| Article | Year |
|---|---|
Cardio-hepatic metabolic derangements and valproic acid.
Topics: Animals; Anticonvulsants; Antimanic Agents; Chemical and Drug Induced Liver Injury; Epigenesis, Gene | 2014 |
2 other studies available for valproic acid and Heart Diseases
| Article | Year |
|---|---|
Effects of enalapril and losartan alone and in combination with sodium valproate on seizures, memory, and cardiac changes in rats.
Topics: Animals; Anticonvulsants; Drug Therapy, Combination; Enalapril; Heart Diseases; Kindling, Neurologic | 2019 |
A child with valproic acid-associated carnitine deficiency and carnitine-responsive cardiac dysfunction.
Topics: Carnitine; Child; Developmental Disabilities; Heart Diseases; Humans; Male; Metabolic Diseases; Myoc | 1992 |