valproic acid has been researched along with Heart Disease, Ischemic in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Svennerholm, K | 1 |
| Bergh, N | 1 |
| Larsson, P | 1 |
| Jern, S | 1 |
| Johansson, G | 1 |
| Biber, B | 1 |
| Haney, M | 1 |
| Kuai, Q | 1 |
| Wang, C | 1 |
| Wang, Y | 2 |
| Li, W | 1 |
| Zhang, G | 1 |
| Qiao, Z | 1 |
| He, M | 1 |
| Wang, X | 1 |
| Jiang, X | 1 |
| Su, L | 1 |
| He, Y | 1 |
| Ren, S | 1 |
| Yu, Q | 1 |
| Ferrari, R | 1 |
| Merli, E | 1 |
| Cicchitelli, G | 1 |
| Mele, D | 1 |
| Fucili, A | 1 |
| Ceconi, C | 1 |
| Meerson, FZ | 1 |
| Gimrikh, EO | 1 |
| Gutsol, LIa | 1 |
| Popov, SV | 1 |
| Plekhanov, IG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940] | Phase 3 | 120 participants (Actual) | Interventional | 2018-05-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for valproic acid and Heart Disease, Ischemic
| Article | Year |
|---|---|
Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review.
Topics: Cardiotonic Agents; Cardiovascular Diseases; Carnitine; Humans; Kidney Failure, Chronic; Liver; Myoc | 2004 |
3 other studies available for valproic acid and Heart Disease, Ischemic
| Article | Year |
|---|---|
Histone deacetylase inhibitor treatment increases coronary t-PA release in a porcine ischemia model.
Topics: Animals; Disease Models, Animal; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Myocardial Isc | 2014 |
Energy metabolism regulated by HDAC inhibitor attenuates cardiac injury in hemorrhagic rat model.
Topics: Animals; Cell Line; Disease Models, Animal; Energy Metabolism; Hemorrhage; Histone Deacetylase Inhib | 2016 |
[The anti-arrhythmic efficacy of sodium valproate].
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Drug Evaluation; Electrocar | 1992 |