Page last updated: 2024-10-26

valproic acid and Headache

valproic acid has been researched along with Headache in 45 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of valproic acid in the treatment of intractable chronic daily headache, unresponsive to traditional prophylactic medications, was examined prospectively in 16 patients."9.08Valproic acid treatment of chronic daily headache. ( Spillane, T; Vijayan, N, 1995)
"To correlate lamotrigine (LTG) serum concentrations (levels) with tolerability in patients with epilepsy."8.82Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy. ( Adams, DJ; Bazil, CW; Buchsbaum, R; Du, Y; Hager, M; Hirsch, LJ; Morrell, MJ; Resor, SR; Spencer, HT; Straka, T; Weintraub, D, 2004)
"Sodium valproate and ibuprofen are drugs with known efficacy in the treatment of headache associated with acute migraine attacks."5.51Intravenous ibuprofen versus sodium valproate in acute migraine attacks in the emergency department: A randomized clinical trial. ( Akbas, I; Ceylan, M; Dogruyol, S; Gur, STA; Kocak, AO; Kocak, MB; Tekyol, D, 2022)
" Compared to other active drugs, it only showed a lower significant effect compared with granisetron regarding headache change while it showed significantly higher effects only with placebo in both rescue medication needs and headache-free symptoms and valproate in only rescue medication need."5.41The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials. ( Abd-ElGawad, M; Abdelhay, HM; Abdelmonem, H; Abdelwadoud, GT; Ahmed, AE; Al-Dardery, NM; Alhosini, ANM; Kamel, MA; Mohamed, SW, 2023)
"One-hundred eighty patients with partial or idiopathic generalized nonabsence epilepsy, aged 6 to 65 years, requiring initiation of treatment with carbamazepine (CBZ), valproate (VPA), phenytoin (PHT), phenobarbital (PB), or primidone (PRM) were randomly allocated to two groups according to an open, prospective parallel-group design."5.09A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. The Italian TDM Study Group in Epilepsy. ( Bartoli, A; Cian, P; Fattore, C; Gatti, G; Jannuzzi, G; Monaco, F; Perucca, E, 2000)
"Thirty-three consecutive patients with primary chronic daily headache were managed according to a treatment pathway which involved sequential administration of divalproex sodium, amitriptyline, amitriptyline plus phenelzine, or methadone."5.09Management of chronic daily headache utilizing a uniform treatment pathway. ( Rothrock, JF, 1999)
"The efficacy of valproic acid in the treatment of intractable chronic daily headache, unresponsive to traditional prophylactic medications, was examined prospectively in 16 patients."5.08Valproic acid treatment of chronic daily headache. ( Spillane, T; Vijayan, N, 1995)
"Concomitant administration of lithium and valproate appears to be safe in patients with bipolar disorder."5.08Pharmacokinetic interactions and side effects resulting from concomitant administration of lithium and divalproex sodium. ( Cavanaugh, JH; Granneman, GR; Schneck, DW; Witt, GF, 1996)
"To correlate lamotrigine (LTG) serum concentrations (levels) with tolerability in patients with epilepsy."4.82Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy. ( Adams, DJ; Bazil, CW; Buchsbaum, R; Du, Y; Hager, M; Hirsch, LJ; Morrell, MJ; Resor, SR; Spencer, HT; Straka, T; Weintraub, D, 2004)
" For the acute treatment of migraine attacks or tension-type headache, ibuprofen (10 mg per kg body weight) or acetaminophen (15 mg per kg body weight) are recommended with highest evidence, intranasal sumatriptan (10 to 20 mg) can be given as second choice."4.81[Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)]. ( Evers, S; Gerber, WD; Naumann, E; Pothmann, R; Uberall, M, 2002)
"Insomnia was more common in the placebo group."2.73Efficacy and safety of quetiapine in combination with lithium or divalproex for maintenance of patients with bipolar I disorder (international trial 126). ( Brecher, M; Eggens, I; Paulsson, B; Persson, I; Suppes, T; Vieta, E, 2008)
" High-fat breakfast or yogurt did not modify either the bioavailability or pharmacokinetic profile of valproate MR granules."2.71Bioequivalence of a new sustained-release formulation of sodium valproate, valproate modified-release granules, compared with existing sustained-release formulations after once- or twice-daily administration. ( Alvarez, JC; Dulac, O, 2005)
"Gabapentin doses >1,800 mg/day were as well tolerated as doses < or =1,800 mg/day and were not associated with more adverse events."2.69Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study. ( Bernstein, P; Faught, RE; Holmes, GL; Magnus-Miller, L; McLean, MJ; Morrell, MJ; Privitera, MD; Rose-Legatt, A; Willmore, LJ, 1999)
" The adverse effect (AE) profile of this combination needs clarification."2.69Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS) Group. ( Faught, E; French, J; Harden, C; Jacobson, M; Montouris, G; Morris, G; Rosenfeld, W, 1999)
"We included 43 patients with migraine without aura in a triple-blind, placebo- and dose-controlled, crossover study of the prophylactic effect of slow-release sodium valproate; 34 patients completed the trial."2.67Sodium valproate has a prophylactic effect in migraine without aura: a triple-blind, placebo-controlled crossover study. ( Brinck, T; Jensen, R; Olesen, J, 1994)
"Pediatric migraine can cause a significant impact on quality of life."2.45[Antiepileptic drugs for the prevention of pediatric migraine]. ( Cuvellier, JC, 2009)
"Acute therapy for athletes with migraines is best managed with sumatriptan or DHE 45 and prophylaxis can be accomplished with verapamil, antidepressants, or valproate."2.40Diagnosis, prophylaxis, and treatment of headaches in the athlete. ( Kaplan, B; Swain, RA, 1997)
"There was a reduction in the number of migraine attacks, and migraine duration and intensity were also reduced in some instances."2.39Divalproex sodium in headache: literature review and clinical guidelines. ( Silberstein, SD, 1996)
"Many migraine sufferers use daily prophylactic therapy to reduce the frequency of their headache attacks."1.43Using a graphical risk tool to examine willingness to take migraine prophylactic medications. ( Golding, AN; Houle, TT; Turner, DP, 2016)
"Headaches are common in the pediatric population, and increase in prevalence with age."1.42Intravenous Sodium Valproate for Acute Pediatric Headache. ( Hansen, M; O'Brien, P; Sheridan, D; Sun, B, 2015)
" We describe four patients in whom such effects occurred after continuous, long-term use of valproate-lamotrigine (at 9 months to 2 years after final antiepileptic drug adjustment)."1.38Late adverse effects of the coadministration of valproate and lamotrigine. ( Moreira, B; Thome-Souza, S; Valente, KD, 2012)
"Headache is a frequent clinical symptom of lateralizing value, which may share common pathophysiology with epileptogenesis among MTLE-HS patients."1.37Hippocampal sclerosis and ipsilateral headache among mesial temporal lobe epilepsy patients. ( Bastos, A; Claudino, LS; Guarnieri, R; Lin, K; Nunes, JC; Queiroz, LP; Walz, R; Zakon, DB, 2011)
""Sinus headache" is a patient's complaint or physician-diagnosis that can have a variety of underlying causes."1.36The response to sodium valproate of patients with sinus headaches with normal endoscopic and CT findings. ( Atighechi, S; Baradaranfar, MH; Dadgarnia, MH, 2010)
"A 19-year-old male who had had complex partial seizures for 15 years was admitted with autonomic complaints and left hemicranial headache, independent from seizures, that he had had for 2 years and were provoked by watching television."1.33Autonomic headache with autonomic seizures: a case report. ( Kaleagasi, H; Ozge, A; Yalçin Tasmertek, F, 2006)
"Headache is a significant problem with the suboccipital approach for acoustic tumor removal."1.30Medical treatment of headache after suboccipital acoustic tumor removal. ( Brandes, JL; Glasscock, ME; Hanson, MB; Jackson, CG, 1998)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (35.56)18.2507
2000's12 (26.67)29.6817
2010's12 (26.67)24.3611
2020's5 (11.11)2.80

Authors

AuthorsStudies
Dogruyol, S1
Gur, STA1
Akbas, I1
Kocak, MB1
Kocak, AO1
Ceylan, M1
Tekyol, D1
Günay, Ç1
Edem, P1
Hız-Kurul, AS1
Yaşar, E1
Yiş, U1
Abdelmonem, H1
Abdelhay, HM1
Abdelwadoud, GT1
Alhosini, ANM1
Ahmed, AE1
Mohamed, SW1
Al-Dardery, NM1
Abd-ElGawad, M1
Kamel, MA1
Diener, HC1
Rizzoli, P1
Lu, PL1
Hodes, JF1
Zheng, X1
Hu, XY1
Ozan, K1
Coskun, Y1
Bora, CK1
Ayten, Y1
Sarchielli, P1
Messina, P1
Cupini, LM1
Tedeschi, G1
Di Piero, V1
Livrea, P1
Pini, LA1
Bernardi, G1
Bono, G1
Sandrini, G1
Caproni, S1
Corbelli, I1
Pisani, F1
Beghi, E1
Calabresi, P1
Sheridan, D1
Sun, B1
O'Brien, P1
Hansen, M1
Turner, DP1
Golding, AN1
Houle, TT1
Jackson, R1
Toubia, N1
Dhaliwal, G1
Bottomley, SS1
Bronze, MS1
Vieta, E1
Suppes, T1
Eggens, I1
Persson, I1
Paulsson, B1
Brecher, M1
Cuvellier, JC1
Dadgarnia, MH1
Atighechi, S1
Baradaranfar, MH1
Kholin, AA1
Voronkova, KV1
Pylaeva, OA1
Petrukhin, AS1
Stewart, JD1
Horvath, R1
Baruffini, E1
Ferrero, I1
Bulst, S1
Watkins, PB1
Fontana, RJ1
Day, CP1
Chinnery, PF1
Smith, AP1
Sani, S1
Kanner, AM1
Stoub, T1
Morrin, M1
Palac, S1
Bergen, DC1
Balabonov, A1
Smith, M1
Whisler, WW1
Byrne, RW1
Nunes, JC1
Zakon, DB1
Claudino, LS1
Guarnieri, R1
Bastos, A1
Queiroz, LP1
Walz, R1
Lin, K1
Bowen, DJ1
Lucas, NL1
Braude, S1
Prakash, S1
Saini, S1
Rana, KR1
Mahato, P1
Thome-Souza, S1
Moreira, B1
Valente, KD1
Oppenheim, C1
Touzé, E1
Meder, JF1
Hirsch, LJ1
Weintraub, D1
Du, Y1
Buchsbaum, R1
Spencer, HT1
Hager, M1
Straka, T1
Bazil, CW1
Adams, DJ1
Resor, SR1
Morrell, MJ2
Frediani, F1
Dulac, O1
Alvarez, JC1
Parisi, P1
Ferri, R1
Pagani, J1
Cecili, M1
Montemitro, E1
Villa, MP1
Ozge, A1
Kaleagasi, H1
Yalçin Tasmertek, F1
Hendler, N1
Cashen, A1
Morrison, C1
Long, D1
Holliday, M1
Mathew, NT2
Rothrock, JF2
Kelly, NM1
Brody, ML1
Golbeck, A1
Jensen, R1
Brinck, T1
Olesen, J1
Vijayan, N1
Spillane, T1
Granneman, GR1
Schneck, DW1
Cavanaugh, JH1
Witt, GF1
Silberstein, SD1
Swain, RA1
Kaplan, B1
Hanson, MB1
Glasscock, ME1
Brandes, JL1
Jackson, CG1
Zed, PJ1
Loewen, PS1
Robinson, G1
McLean, MJ1
Willmore, LJ1
Privitera, MD1
Faught, RE1
Holmes, GL1
Magnus-Miller, L1
Bernstein, P1
Rose-Legatt, A1
Faught, E1
Morris, G1
Jacobson, M1
French, J1
Harden, C1
Montouris, G1
Rosenfeld, W1
Matsuo, F1
Jannuzzi, G1
Cian, P1
Fattore, C1
Gatti, G1
Bartoli, A1
Monaco, F1
Perucca, E1
Packard, RC1
Evers, S1
Pothmann, R1
Uberall, M1
Naumann, E1
Gerber, WD1
Ali, S1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study of Prophylactic Management of Lamotrigine for Bipolar Disorder in Pregnant Women[NCT03774641]20 participants (Anticipated)Observational2018-12-03Recruiting
Bioequivalence Study of Sodium Valproate and Valproic Acid Extended Release Tablets in Healthy Human Volunteers[NCT05641649]Phase 416 participants (Anticipated)Interventional2023-08-06Active, not recruiting
A Prospective Study on Long-term Outcome and Potential Usefulness fo an Intervention Aimed at Reducing Adverse Effects in Patients With Refractory Epilepsy[NCT03939507]1,000 participants (Actual)Interventional2006-11-06Completed
A Randomized, Single-Center, Double-Blind, Parallel, Sham-Controlled Study of Gammacore Sapphire (Non-Invasive Vagus Nerve Stimulator) for the Acute and Preventive Treatment of Post-Traumatic Headache (GAP-PTH)[NCT04071743]0 participants (Actual)Interventional2020-01-01Withdrawn (stopped due to Primary Investigator left UT Southwestern and was not replaced.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for valproic acid and Headache

ArticleYear
The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials.
    BMC neurology, 2023, Jun-08, Volume: 23, Issue:1

    Topics: Chlorpromazine; Granisetron; Headache; Humans; Ketorolac; Metoclopramide; Migraine Disorders; Nausea

2023
Chronic migraine and medication overuse.
    Handbook of clinical neurology, 2023, Volume: 198

    Topics: Headache; Humans; Migraine Disorders; Prescription Drug Overuse; Valproic Acid

2023
[Antiepileptic drugs for the prevention of pediatric migraine].
    Revue neurologique, 2009, Volume: 165, Issue:12

    Topics: Adolescent; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Tolerance; Fructose; G

2009
[Efficacy and safety of intravenous valproates].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2010, Volume: 110, Issue:3 Suppl 2

    Topics: Anticonvulsants; Headache; Humans; Injections, Intravenous; Status Epilepticus; Valproic Acid

2010
Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy.
    Neurology, 2004, Sep-28, Volume: 63, Issue:6

    Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Eruptions; Drug Interactions; Drug Therapy,

2004
Anticonvulsant drugs in primary headaches prophylaxis.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2004, Volume: 25 Suppl 3

    Topics: Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fruct

2004
Divalproex sodium in headache: literature review and clinical guidelines.
    Headache, 1996, Volume: 36, Issue:9

    Topics: Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Headache; Humans; Migraine Disorders

1996
Diagnosis, prophylaxis, and treatment of headaches in the athlete.
    Southern medical journal, 1997, Volume: 90, Issue:9

    Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic;

1997
Medication-induced headache: overview and systematic review of therapeutic approaches.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:1

    Topics: Amitriptyline; Analgesics; Anti-Inflammatory Agents; Chronic Disease; Ergolines; Headache; Humans; M

1999
Lamotrigine.
    Epilepsia, 1999, Volume: 40 Suppl 5

    Topics: Adolescent; Adult; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Diplopia; Dizziness; D

1999
[Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)].
    Schmerz (Berlin, Germany), 2002, Volume: 16, Issue:1

    Topics: Acetaminophen; Adrenergic beta-Antagonists; Age Factors; Analgesics, Non-Narcotic; Biofeedback, Psyc

2002

Trials

12 trials available for valproic acid and Headache

ArticleYear
Intravenous ibuprofen versus sodium valproate in acute migraine attacks in the emergency department: A randomized clinical trial.
    The American journal of emergency medicine, 2022, Volume: 55

    Topics: Double-Blind Method; Emergency Service, Hospital; Headache; Humans; Ibuprofen; Migraine Disorders; P

2022
Sodium valproate in migraine without aura and medication overuse headache: a randomized controlled trial.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:8

    Topics: Adolescent; Adult; Age Factors; Analysis of Variance; Antimanic Agents; Disability Evaluation; Doubl

2014
Efficacy and safety of quetiapine in combination with lithium or divalproex for maintenance of patients with bipolar I disorder (international trial 126).
    Journal of affective disorders, 2008, Volume: 109, Issue:3

    Topics: Antipsychotic Agents; Bipolar Disorder; Demography; Dibenzothiazepines; Disorders of Excessive Somno

2008
Bioequivalence of a new sustained-release formulation of sodium valproate, valproate modified-release granules, compared with existing sustained-release formulations after once- or twice-daily administration.
    Pharmacotherapy, 2005, Volume: 25, Issue:1

    Topics: Adult; Area Under Curve; Chemistry, Pharmaceutical; Cross-Over Studies; Delayed-Action Preparations;

2005
Sodium valproate has a prophylactic effect in migraine without aura: a triple-blind, placebo-controlled crossover study.
    Neurology, 1994, Volume: 44, Issue:4

    Topics: Adult; Female; Headache; Humans; Male; Middle Aged; Migraine Disorders; Muscle Contraction; Placebos

1994
Valproic acid treatment of chronic daily headache.
    Headache, 1995, Volume: 35, Issue:9

    Topics: Adult; Aged; Chronic Disease; Female; Headache; Humans; Male; Middle Aged; Prospective Studies; Valp

1995
Pharmacokinetic interactions and side effects resulting from concomitant administration of lithium and divalproex sodium.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:5

    Topics: Adult; Bipolar Disorder; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Interactions

1996
Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study.
    Epilepsia, 1999, Volume: 40, Issue:7

    Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Asthenia; Carbamazepine; Cycl

1999
Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS) Group.
    Epilepsia, 1999, Volume: 40, Issue:8

    Topics: Adolescent; Adult; Child; Dizziness; Drug Eruptions; Drug Hypersensitivity; Drug Therapy, Combinatio

1999
A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. The Italian TDM Study Group in Epilepsy.
    Epilepsia, 2000, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dizziness; Drug Administration Sched

2000
Management of chronic daily headache utilizing a uniform treatment pathway.
    Headache, 1999, Volume: 39, Issue:9

    Topics: Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Dru

1999
Valproate in the treatment of persistent chronic daily headache. An open label study.
    Headache, 1991, Volume: 31, Issue:2

    Topics: Chronic Disease; Double-Blind Method; Headache; Humans; Prospective Studies; Valproic Acid

1991

Other Studies

22 other studies available for valproic acid and Headache

ArticleYear
Recurrent painful ophthalmoplegic neuropathy: a report of two new pediatric cases.
    The Turkish journal of pediatrics, 2022, Volume: 64, Issue:3

    Topics: Child; Child, Preschool; Female; Headache; Humans; Magnetic Resonance Imaging; Ophthalmoplegia; Opht

2022
Reversible Splenial Lesion Syndrome with Some Novel Causes and Clinical Manifestations.
    Internal medicine (Tokyo, Japan), 2020, Oct-15, Volume: 59, Issue:20

    Topics: Adult; Anticonvulsants; Brain Diseases; Carbamazepine; Causality; Corpus Callosum; Female; Headache;

2020
Valproic acid-induced nocturnal enuresis in pediatric patients.
    Nigerian journal of clinical practice, 2019, Volume: 22, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Headache; Humans; Incidence;

2019
Intravenous Sodium Valproate for Acute Pediatric Headache.
    The Journal of emergency medicine, 2015, Volume: 49, Issue:4

    Topics: Acute Disease; Administration, Intravenous; Adolescent; Child; Emergency Service, Hospital; Enzyme I

2015
Using a graphical risk tool to examine willingness to take migraine prophylactic medications.
    Pain, 2016, Volume: 157, Issue:10

    Topics: Amines; Analgesics; Antidepressive Agents; Antihypertensive Agents; Cross-Sectional Studies; Cyclohe

2016
A confusing case of confusion. Acute porphyrias.
    The Journal of the Oklahoma State Medical Association, 2008, Volume: 101, Issue:4

    Topics: Acidosis, Lactic; Acute Disease; Anticonvulsants; Brain; Confusion; Diagnosis, Differential; Diet, R

2008
The response to sodium valproate of patients with sinus headaches with normal endoscopic and CT findings.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2010, Volume: 267, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Delayed-Action Preparations; Drug Administration Schedule; Endos

2010
Polymerase γ gene POLG determines the risk of sodium valproate-induced liver toxicity.
    Hepatology (Baltimore, Md.), 2010, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Amino Acid Substitution; Bipolar Disorder; Child; Child, Preschool; Diffuse Cereb

2010
Medically intractable temporal lobe epilepsy in patients with normal MRI: surgical outcome in twenty-one consecutive patients.
    Seizure, 2011, Volume: 20, Issue:6

    Topics: Adult; Age of Onset; Anticonvulsants; Cross-Sectional Studies; Educational Status; Electroencephalog

2011
Hippocampal sclerosis and ipsilateral headache among mesial temporal lobe epilepsy patients.
    Seizure, 2011, Volume: 20, Issue:6

    Topics: Adult; Age of Onset; Anticonvulsants; Cross-Sectional Studies; Educational Status; Electroencephalog

2011
Persistent febrile illness with multisystem organ failure associated with clozapine.
    Internal medicine journal, 2012, Volume: 42, Issue:1

    Topics: Abdominal Pain; Adult; Antipsychotic Agents; Clozapine; Combined Modality Therapy; Diagnostic Errors

2012
Refining clinical features and therapeutic options of new daily persistent headache: a retrospective study of 63 patients in India.
    The journal of headache and pain, 2012, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Aged; Analgesics; Brain; Female; Follow-Up Studies; Headache; Humans; India; Magn

2012
Late adverse effects of the coadministration of valproate and lamotrigine.
    Pediatric neurology, 2012, Volume: 47, Issue:1

    Topics: Adolescent; Anticonvulsants; Ataxia; Child; Drug Therapy, Combination; Epilepsy; Female; Headache; H

2012
[Case no 3. MELAS syndrome].
    Journal de radiologie, 2003, Volume: 84, Issue:1

    Topics: Adolescent; Diagnosis, Differential; GABA Agents; Headache; Humans; Magnetic Resonance Imaging; Male

2003
Ictal video-polysomnography and EEG spectral analysis in a child with severe Panayiotopoulos syndrome.
    Epileptic disorders : international epilepsy journal with videotape, 2005, Volume: 7, Issue:4

    Topics: Anticonvulsants; Child; Electroencephalography; Epilepsies, Partial; Eye Movements; Hallucinations;

2005
Autonomic headache with autonomic seizures: a case report.
    The journal of headache and pain, 2006, Volume: 7, Issue:5

    Topics: Anticonvulsants; Autonomic Nervous System; Diagnosis, Differential; Electroencephalography; Epilepsy

2006
Divalproex sodium and other medications for headache following craniotomy for acoustic neuroma.
    Headache, 1995, Volume: 35, Issue:8

    Topics: Anticonvulsants; Craniotomy; Female; Headache; Humans; Male; Middle Aged; Neuroma, Acoustic; Postope

1995
Valproate in intractable headache.
    Cephalalgia : an international journal of headache, 1994, Volume: 14, Issue:3

    Topics: Brain; Chronic Disease; Headache; Humans; Migraine Disorders; Neurons; Valproic Acid

1994
A differential response to treatment with divalproex sodium in patients with intractable headache.
    Cephalalgia : an international journal of headache, 1994, Volume: 14, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Fo

1994
Drugs for psychiatric disorders.
    The Medical letter on drugs and therapeutics, 1997, Apr-11, Volume: 39, Issue:998

    Topics: Aged; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety; Benzodi

1997
Medical treatment of headache after suboccipital acoustic tumor removal.
    The Laryngoscope, 1998, Volume: 108, Issue:8 Pt 1

    Topics: Adult; Cerebellar Neoplasms; Cerebellopontine Angle; Craniotomy; Drug Therapy, Combination; Female;

1998
Treatment of chronic daily posttraumatic headache with divalproex sodium.
    Headache, 2000, Volume: 40, Issue:9

    Topics: Chronic Disease; Craniocerebral Trauma; Follow-Up Studies; GABA Agents; Headache; Humans; Recurrence

2000