valproic acid has been researched along with Graft-Versus-Host Disease in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproic acid (VPA) was described as a histone deacetylase inhibitor that had anti-inflammatory effects and reduced the production of proinflammatory cytokines in experimental autoimmune disease models." | 5.42 | Valproic Acid Ameliorates Graft-versus-Host Disease by Downregulating Th1 and Th17 Cells. ( Chang, L; Chen, Z; Dou, HB; Fang, WY; Gao, WH; Hu, J; Huang, MM; Long, J; Shan, JH; Shen, Y; Wang, Y; Wang, YY; Wu, YN; Zhu, J, 2015) |
| "Valproic acid (VPA) was described as a histone deacetylase inhibitor that had anti-inflammatory effects and reduced the production of proinflammatory cytokines in experimental autoimmune disease models." | 1.42 | Valproic Acid Ameliorates Graft-versus-Host Disease by Downregulating Th1 and Th17 Cells. ( Chang, L; Chen, Z; Dou, HB; Fang, WY; Gao, WH; Hu, J; Huang, MM; Long, J; Shan, JH; Shen, Y; Wang, Y; Wang, YY; Wu, YN; Zhu, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Long, J | 1 |
| Chang, L | 1 |
| Shen, Y | 1 |
| Gao, WH | 1 |
| Wu, YN | 1 |
| Dou, HB | 1 |
| Huang, MM | 1 |
| Wang, Y | 1 |
| Fang, WY | 1 |
| Shan, JH | 1 |
| Wang, YY | 1 |
| Zhu, J | 1 |
| Chen, Z | 1 |
| Hu, J | 1 |
1 other study available for valproic acid and Graft-Versus-Host Disease
| Article | Year |
|---|---|
Valproic Acid Ameliorates Graft-versus-Host Disease by Downregulating Th1 and Th17 Cells.
Topics: Animals; Bone Marrow Transplantation; Cell Differentiation; Disease Models, Animal; Female; Graft vs | 2015 |