valproic acid has been researched along with Glomerulosclerosis, Focal Segmental in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Glomerulosclerosis, Focal Segmental: A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we compared the effect of two HDAC inhibitors, trichostatin A and valproic acid, in an experimental model of kidney fibrosis." | 7.79 | Comparison of trichostatin A and valproic acid treatment regimens in a mouse model of kidney fibrosis. ( Geers, C; Mannaerts, I; Pauwels, M; Van Beneden, K; Van den Branden, C; van Grunsven, LA; Wissing, KM, 2013) |
| " In this study we compared the effect of two HDAC inhibitors, trichostatin A and valproic acid, in an experimental model of kidney fibrosis." | 3.79 | Comparison of trichostatin A and valproic acid treatment regimens in a mouse model of kidney fibrosis. ( Geers, C; Mannaerts, I; Pauwels, M; Van Beneden, K; Van den Branden, C; van Grunsven, LA; Wissing, KM, 2013) |
| "Valproic acid was proved to be effective in reducing the number of attacks over 4 months." | 1.30 | Periodic discharge of adrenocorticotropin and vasopressin associated with focal glomerulosclerosis. ( Fujieda, M; Kurashige, T; Machida, Y; Maeda, A; Maeda, H; Naruse, K; Okada, T; Ushida, M; Wakiguchi, H; Yokoyama, W, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Beneden, K | 2 |
| Geers, C | 2 |
| Pauwels, M | 2 |
| Mannaerts, I | 2 |
| Wissing, KM | 1 |
| Van den Branden, C | 2 |
| van Grunsven, LA | 2 |
| Verbeelen, D | 1 |
| Ackoundou-N'guessan, C | 1 |
| Canaud, B | 1 |
| Leray-Moragues, H | 1 |
| Droz, D | 1 |
| Baldet, P | 1 |
| Pages, M | 1 |
| Yokoyama, W | 1 |
| Fujieda, M | 1 |
| Okada, T | 1 |
| Maeda, H | 1 |
| Ushida, M | 1 |
| Machida, Y | 1 |
| Naruse, K | 1 |
| Maeda, A | 1 |
| Wakiguchi, H | 1 |
| Kurashige, T | 1 |
4 other studies available for valproic acid and Glomerulosclerosis, Focal Segmental
| Article | Year |
|---|---|
Comparison of trichostatin A and valproic acid treatment regimens in a mouse model of kidney fibrosis.
Topics: Acetylation; Animals; Doxorubicin; Female; Fibrosis; Glomerulosclerosis, Focal Segmental; Histone De | 2013 |
Valproic acid attenuates proteinuria and kidney injury.
Topics: Acute Kidney Injury; Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Doxorubicin; Drug | 2011 |
Collapsing focal segmental glomerulosclerosis as a possible complication of valproic acid.
Topics: Adult; Anticonvulsants; Drug Administration Schedule; Glomerulosclerosis, Focal Segmental; Humans; M | 2007 |
Periodic discharge of adrenocorticotropin and vasopressin associated with focal glomerulosclerosis.
Topics: Adrenocorticotropic Hormone; Child; Glomerulosclerosis, Focal Segmental; Humans; Kidney Failure, Chr | 1998 |