valproic acid has been researched along with Gingival Hyperplasia in 7 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Gingival Hyperplasia: Non-inflammatory enlargement of the gingivae produced by factors other than local irritation. It is characteristically due to an increase in the number of cells. (From Jablonski's Dictionary of Dentistry, 1992, p400)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The problem of phenytoin-induced gingival hyperplasia is dicussed within the context of consultative planning between oral care practitioners and the physician managing the epilepsy." | 7.66 | Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion. ( Kirkham, DB; Reynolds, NC, 1980) |
| "Drug-influenced gingival overgrowth is an unaesthetic overgrowth of gingiva principally associated with intake of drugs like phenytoin, cyclosporin A and nifedipine." | 3.78 | Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report. ( Dhingra, K; Prakash, S, 2012) |
| "The problem of phenytoin-induced gingival hyperplasia is dicussed within the context of consultative planning between oral care practitioners and the physician managing the epilepsy." | 3.66 | Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion. ( Kirkham, DB; Reynolds, NC, 1980) |
| "The % of gingival hyperplasia was significantly higher (P less than 0." | 1.27 | The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients. ( Seymour, RA; Smith, DG; Turnbull, DN, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patil, RB | 1 |
| Urs, P | 1 |
| Kiran, S | 1 |
| Bargale, SD | 1 |
| Dhingra, K | 1 |
| Prakash, S | 1 |
| Rodríguez-Vázquez, M | 1 |
| Carrascosa-Romero, MC | 1 |
| Pardal-Fernández, JM | 1 |
| Iniesta, I | 1 |
| Reynolds, NC | 1 |
| Kirkham, DB | 1 |
| Syrjänen, SM | 1 |
| Syrjänen, KJ | 1 |
| Behari, M | 1 |
| Seymour, RA | 1 |
| Smith, DG | 1 |
| Turnbull, DN | 1 |
7 other studies available for valproic acid and Gingival Hyperplasia
| Article | Year |
|---|---|
Global developmental delay with sodium valproate-induced gingival hyperplasia.
Topics: Child; Child, Preschool; Combined Modality Therapy; Developmental Disabilities; Female; Follow-Up St | 2014 |
Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report.
Topics: Anticonvulsants; Denture, Complete; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Gingiva; Ging | 2012 |
Congenital gingival hyperplasia in a neonate with foetal valproate syndrome.
Topics: Adult; Anticonvulsants; Apgar Score; Craniofacial Abnormalities; Dose-Response Relationship, Drug; E | 2007 |
Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion.
Topics: Adolescent; Epilepsy; Female; Gingival Hyperplasia; Humans; Phenytoin; Primidone; Valproic Acid | 1980 |
Hyperplastic gingivitis in a child receiving sodium valproate treatment.
Topics: Gingiva; Gingival Hyperplasia; Humans; Infant; Male; Valproic Acid | 1979 |
Gingival hyperplasia due to sodium valproate.
Topics: Child; Epilepsies, Myoclonic; Female; Gingival Hyperplasia; Humans; Valproic Acid | 1991 |
The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients.
Topics: Adolescent; Adult; Aged; Alveolar Process; Bone Resorption; Cross-Sectional Studies; Dental Plaque I | 1985 |