valproic acid has been researched along with Genome Instability in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxyurea (HU) treatment, which is known to eliminate EBV episomes, shifted EBV replication to earlier times in the cell cycle." | 1.35 | Epstein-Barr virus episome stability is coupled to a delay in replication timing. ( Lieberman, PM; Snyder, AR; Zhou, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Santoro, F | 1 |
| Botrugno, OA | 1 |
| Dal Zuffo, R | 1 |
| Pallavicini, I | 1 |
| Matthews, GM | 1 |
| Cluse, L | 1 |
| Barozzi, I | 1 |
| Senese, S | 1 |
| Fornasari, L | 1 |
| Moretti, S | 1 |
| Altucci, L | 1 |
| Pelicci, PG | 1 |
| Chiocca, S | 1 |
| Johnstone, RW | 1 |
| Minucci, S | 1 |
| Wiegmans, AP | 1 |
| Yap, PY | 1 |
| Ward, A | 1 |
| Lim, YC | 1 |
| Khanna, KK | 1 |
| Zhou, J | 1 |
| Snyder, AR | 1 |
| Lieberman, PM | 1 |
3 other studies available for valproic acid and Genome Instability
| Article | Year |
|---|---|
A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplasti | 2013 |
Differences in Expression of Key DNA Damage Repair Genes after Epigenetic-Induced BRCAness Dictate Synthetic Lethality with PARP1 Inhibition.
Topics: Antineoplastic Agents; Benzimidazoles; BRCA1 Protein; Cell Line, Tumor; Cell Survival; Depsipeptides | 2015 |
Epstein-Barr virus episome stability is coupled to a delay in replication timing.
Topics: Binding Sites; DNA Replication; DNA, Viral; Genome, Viral; Genomic Instability; HeLa Cells; Herpesvi | 2009 |