valproic acid has been researched along with Gastrointestinal Hemorrhage in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hyperammonemic coma is determined through a complicated differential diagnosis, and although it can also be induced as a side effect of valproate (VPA), this cause is frequently unrecognized or confused with upper gastrointestinal hemorrhage (UGH)-induced hepatic encephalopathy." | 2.55 | Hyperammonemic coma after craniotomy: Hepatic encephalopathy from upper gastrointestinal hemorrhage or valproate side effect?: Case report and literature review. ( Gao, L; Guo, X; Wei, J; Xing, B; Xu, Z, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, X | 1 |
| Wei, J | 1 |
| Gao, L | 1 |
| Xing, B | 1 |
| Xu, Z | 1 |
| Kennedy, J | 1 |
| Simmonds, L | 1 |
| Orme, R | 1 |
| Doherty, W | 1 |
| de Bernardis, E | 1 |
| Caruso, A | 1 |
| Cutuli, VM | 1 |
| Lucenti, A | 1 |
| Villari, L | 1 |
| Amico-Roxas, M | 1 |
1 review available for valproic acid and Gastrointestinal Hemorrhage
| Article | Year |
|---|---|
Hyperammonemic coma after craniotomy: Hepatic encephalopathy from upper gastrointestinal hemorrhage or valproate side effect?: Case report and literature review.
Topics: Anticonvulsants; Coma; Craniotomy; Diagnosis, Differential; Female; Gastrointestinal Hemorrhage; Hep | 2017 |
2 other studies available for valproic acid and Gastrointestinal Hemorrhage
| Article | Year |
|---|---|
An unusual case of
Topics: Abdominal Pain; Acute Kidney Injury; Aged; Anti-Bacterial Agents; Anticonvulsants; Critical Care; En | 2017 |
Effects of GABAergic drugs on ethanol-induced gastric lesions.
Topics: Animals; Baclofen; Bicuculline; Diazepam; Ethanol; GABA Antagonists; gamma-Aminobutyric Acid; Gastro | 1993 |