valproic acid has been researched along with Fibrocystic Breast Disease in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Fibrocystic Breast Disease: A common and benign breast disease characterized by varying degree of fibrocystic changes in the breast tissue. There are three major patterns of morphological changes, including FIBROSIS, formation of CYSTS, and proliferation of glandular tissue (adenosis). The fibrocystic breast has a dense irregular, lumpy, bumpy consistency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In six patients with epilepsy and fibrocystic breast disease the concentration in serum of antiepileptic drugs was obtained before, during, and after danazol therapy." | 3.67 | Clinically significant danazol-carbamazepine interaction. ( Haidukewych, D; Lichten, EM; Zielinski, JJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zielinski, JJ | 1 |
| Lichten, EM | 1 |
| Haidukewych, D | 1 |
1 other study available for valproic acid and Fibrocystic Breast Disease
| Article | Year |
|---|---|
Clinically significant danazol-carbamazepine interaction.
Topics: Adult; Carbamazepine; Danazol; Drug Interactions; Epilepsy; Female; Fibrocystic Breast Disease; Huma | 1987 |