Page last updated: 2024-10-26

valproic acid and Femoral Fractures

valproic acid has been researched along with Femoral Fractures in 3 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Femoral Fractures: Fractures of the femur.

Research Excerpts

ExcerptRelevanceReference
"We have demonstrated previously that valproic acid (VPA), a histone deacetylase inhibitor, can improve survival in lethal models of hemorrhagic shock."3.75Surviving blood loss without blood transfusion in a swine poly-trauma model. ( Alam, HB; Butt, MU; Demoya, M; Duggan, M; Fukudome, EY; Li, Y; Liu, B; Shuja, F; Velmahos, GC; Zacharias, N, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alam, HB1
Shuja, F1
Butt, MU1
Duggan, M1
Li, Y1
Zacharias, N1
Fukudome, EY1
Liu, B1
Demoya, M1
Velmahos, GC1
Dhillon, N1
Högler, W1
Pavlakis, SG1
Chusid, RL1
Roye, DP1
Nordli, DR1

Other Studies

3 other studies available for valproic acid and Femoral Fractures

ArticleYear
Surviving blood loss without blood transfusion in a swine poly-trauma model.
    Surgery, 2009, Volume: 146, Issue:2

    Topics: Animals; beta Catenin; Blood Pressure; Blood Transfusion; Female; Femoral Fractures; Glycogen Syntha

2009
Fractures and Fanconi syndrome due to prolonged sodium valproate use.
    Neuropediatrics, 2011, Volume: 42, Issue:3

    Topics: Child; Disabled Children; Epilepsies, Myoclonic; Fanconi Syndrome; Female; Femoral Fractures; Humans

2011
Valproate therapy: predisposition to bone fracture?
    Pediatric neurology, 1998, Volume: 19, Issue:2

    Topics: Adolescent; Bone and Bones; Disease Susceptibility; Epilepsy; Female; Femoral Fractures; Foot; Fract

1998