valproic acid has been researched along with Facies in 9 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Facies: The appearance of the face that is often characteristic of a disease or pathological condition, as the elfin facies of WILLIAMS SYNDROME or the mongoloid facies of DOWN SYNDROME. (Random House Unabridged Dictionary, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " A 13-year-old girl with genetically confirmed Pitt-Hopkins syndrome with uncontrolled seizures, while on treatment with levetiracetam and valproic acid, was started on perampanel, reaching seizure control." | 7.91 | Perampanel-induced hair curling in a patient with epilepsy associated with Pitt Hopkins syndrome. ( Calle-Lopez, Y; Knight, EP; Kotagal, P, 2019) |
| "Valproic acid (VPA) is a known teratogenic drug." | 5.40 | Middle and inner ear malformations in two siblings exposed to valproic acid during pregnancy: a case report. ( Casselman, J; De Kegel, A; Dhooge, I; Janssens, S; Maes, L; Van Houtte, E, 2014) |
| " A 13-year-old girl with genetically confirmed Pitt-Hopkins syndrome with uncontrolled seizures, while on treatment with levetiracetam and valproic acid, was started on perampanel, reaching seizure control." | 3.91 | Perampanel-induced hair curling in a patient with epilepsy associated with Pitt Hopkins syndrome. ( Calle-Lopez, Y; Knight, EP; Kotagal, P, 2019) |
| "Valproic acid (VPA) is a known teratogenic drug." | 1.40 | Middle and inner ear malformations in two siblings exposed to valproic acid during pregnancy: a case report. ( Casselman, J; De Kegel, A; Dhooge, I; Janssens, S; Maes, L; Van Houtte, E, 2014) |
| "Focal seizures were more frequent during drowsiness and sleep." | 1.39 | Epilepsy in Mowat-Wilson syndrome: delineation of the electroclinical phenotype. ( Bianchi, P; Bonetti, S; Boni, A; Buoni, S; Cecconi, I; Cerruti Mainardi, P; Cordelli, DM; Della Giustina, E; Doz, M; Epifanio, R; Faravelli, F; Ferrari, AR; Franzoni, E; Garavelli, L; Gelmini, C; Giordano, L; Grasso, M; Grioni, D; Grosso, S; Guerra, A; Licata, F; Malbora, B; Mammi, I; Mari, F; Mazzanti, L; Mostardini, R; Pantaleoni, C; Pellicciari, A; Poch-Olivé, ML; Rivieri, F; Rosato, S; Savasta, S; Seri, M; Simonte, G; Sorge, G; Tarani, L; Terazzi, E; Wischmeijer, A; Zanotta, N; Zollino, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 4 (44.44) | 2.80 |
| Authors | Studies |
|---|---|
| Ju, Y | 1 |
| Ji, TY | 1 |
| Hofmeister, B | 2 |
| von Stülpnagel, C | 2 |
| Berweck, S | 2 |
| Abicht, A | 1 |
| Kluger, G | 2 |
| Weber, P | 2 |
| Calle-Lopez, Y | 1 |
| Kotagal, P | 1 |
| Knight, EP | 1 |
| Finsterer, J | 1 |
| Van Houtte, E | 1 |
| Casselman, J | 1 |
| Janssens, S | 1 |
| De Kegel, A | 1 |
| Maes, L | 1 |
| Dhooge, I | 1 |
| Cordelli, DM | 1 |
| Garavelli, L | 1 |
| Savasta, S | 1 |
| Guerra, A | 1 |
| Pellicciari, A | 1 |
| Giordano, L | 1 |
| Bonetti, S | 1 |
| Cecconi, I | 1 |
| Wischmeijer, A | 1 |
| Seri, M | 1 |
| Rosato, S | 1 |
| Gelmini, C | 1 |
| Della Giustina, E | 1 |
| Ferrari, AR | 1 |
| Zanotta, N | 1 |
| Epifanio, R | 1 |
| Grioni, D | 1 |
| Malbora, B | 1 |
| Mammi, I | 1 |
| Mari, F | 1 |
| Buoni, S | 1 |
| Mostardini, R | 1 |
| Grosso, S | 1 |
| Pantaleoni, C | 1 |
| Doz, M | 1 |
| Poch-Olivé, ML | 1 |
| Rivieri, F | 1 |
| Sorge, G | 1 |
| Simonte, G | 1 |
| Licata, F | 1 |
| Tarani, L | 1 |
| Terazzi, E | 1 |
| Mazzanti, L | 1 |
| Cerruti Mainardi, P | 1 |
| Boni, A | 1 |
| Faravelli, F | 1 |
| Grasso, M | 1 |
| Bianchi, P | 1 |
| Zollino, M | 1 |
| Franzoni, E | 1 |
| Kini, U | 1 |
| Adab, N | 1 |
| Vinten, J | 1 |
| Fryer, A | 1 |
| Clayton-Smith, J | 1 |
| Rodríguez-Vázquez, M | 1 |
| Carrascosa-Romero, MC | 1 |
| Pardal-Fernández, JM | 1 |
| Iniesta, I | 1 |
9 other studies available for valproic acid and Facies
| Article | Year |
|---|---|
[Clinical features of epilepsy in 5 children with Mowat-Wilson syndrome].
Topics: Child; Electroencephalography; Epilepsy; Facies; Female; Hirschsprung Disease; Humans; Intellectual | 2022 |
Cooccurrence of Two Different Genetic Diseases: A Case of Valproic Acid Hepatotoxicity in Nicolaides-Baraitser Syndrome (SMARCA2 Mutation)-Due to a POLG1-Related Effect?
Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Child; DNA Polymerase gamma; Facies; Female | 2020 |
Perampanel-induced hair curling in a patient with epilepsy associated with Pitt Hopkins syndrome.
Topics: Adolescent; Anticonvulsants; Epilepsy; Facies; Female; Hair; Humans; Hyperventilation; Intellectual | 2019 |
Overlapping Phenotype from Double Trouble SMARCA2 and POLG1 Variants c.2556A > C and c.3708G > T, Respectively.
Topics: Chemical and Drug Induced Liver Injury; Facies; Foot Deformities, Congenital; Humans; Hypotrichosis; | 2020 |
Response To: Overlapping Phenotype from Double Trouble SMARCA2 and POLG1 Variants c.2556A > C and c.3708G > T, Respectively.
Topics: Chemical and Drug Induced Liver Injury; Facies; Foot Deformities, Congenital; Humans; Hypotrichosis; | 2020 |
Middle and inner ear malformations in two siblings exposed to valproic acid during pregnancy: a case report.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Child, Preschool; Developmental Disabil | 2014 |
Epilepsy in Mowat-Wilson syndrome: delineation of the electroclinical phenotype.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; DNA Mutational Analysis; Electroencephalograph | 2013 |
Dysmorphic features: an important clue to the diagnosis and severity of fetal anticonvulsant syndromes.
Topics: Abnormalities, Drug-Induced; Adolescent; Anthropometry; Anticonvulsants; Carbamazepine; Child; Child | 2006 |
Congenital gingival hyperplasia in a neonate with foetal valproate syndrome.
Topics: Adult; Anticonvulsants; Apgar Score; Craniofacial Abnormalities; Dose-Response Relationship, Drug; E | 2007 |