valproic acid has been researched along with Eye Abnormalities in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Eye Abnormalities: Congenital absence of or defects in structures of the eye; may also be hereditary.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of valproic acid during pregnancy has been associated with adverse fetal outcomes, including major and minor congenital malformations, intrauterine growth retardation (IUGR), hyperbilirubinemia, hepatotoxicity, transient hyperglycemia, and fetal and neonatal distress." | 3.71 | Septo-optic dysplasia as a manifestation of valproic acid embryopathy. ( Braddock, SR; McMahon, CL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McMahon, CL | 1 |
| Braddock, SR | 1 |
| Glover, SJ | 1 |
| Quinn, AG | 1 |
| Barter, P | 1 |
| Hart, J | 1 |
| Moore, SJ | 1 |
| Dean, JC | 1 |
| Turnpenny, PD | 1 |
2 other studies available for valproic acid and Eye Abnormalities
| Article | Year |
|---|---|
Septo-optic dysplasia as a manifestation of valproic acid embryopathy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Antimanic Agents; Child, Preschool | 2001 |
Ophthalmic findings in fetal anticonvulsant syndrome(s).
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Ep | 2002 |