Page last updated: 2024-10-26

valproic acid and Experimental Neoplasms

valproic acid has been researched along with Experimental Neoplasms in 6 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
" In contrast, an acceleration of the growth and a reduction of the survival time were observed in females dosed with alpha-MPG or DPA."1.26[Effect of alpha-mercaptopropionylglycine (alpha-MPG) and sodium dipropylacetate (DPA) on antibody formation (IV). Tumor immunity (author's transl)]. ( Koda, A; Mori, H; Saiki, I, 1978)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Valiulytė, I1
Curkūnavičiūtė, R1
Ribokaitė, L1
Kazlauskas, A1
Vaitkevičiūtė, M1
Skauminas, K1
Valančiūtė, A1
Stedt, H1
Samaranayake, H1
Pikkarainen, J1
Määttä, AM1
Alasaarela, L1
Airenne, K1
Ylä-Herttuala, S1
Osuka, S1
Takano, S1
Watanabe, S1
Ishikawa, E1
Yamamoto, T1
Matsumura, A1
Moschidou, D1
Mukherjee, S1
Blundell, MP1
Jones, GN1
Atala, AJ1
Thrasher, AJ1
Fisk, NM1
De Coppi, P1
Guillot, PV1
Höti, N1
Chowdhury, W1
Hsieh, JT1
Sachs, MD1
Lupold, SE1
Rodriguez, R1
Mori, H1
Saiki, I1
Koda, A1

Other Studies

6 other studies available for valproic acid and Experimental Neoplasms

ArticleYear
The Anti-Tumorigenic Activity of Sema3C in the Chick Embryo Chorioallantoic Membrane Model.
    International journal of molecular sciences, 2019, Nov-12, Volume: 20, Issue:22

    Topics: Animals; Cell Line, Tumor; Chick Embryo; Chorioallantoic Membrane; Glioblastoma; Humans; Neoplasm In

2019
Improved therapeutic effect on malignant glioma with adenoviral suicide gene therapy combined with temozolomide.
    Gene therapy, 2013, Volume: 20, Issue:12

    Topics: Adenoviruses, Human; Animals; Antineoplastic Agents, Alkylating; Antiviral Agents; Combined Modality

2013
Valproic acid inhibits angiogenesis in vitro and glioma angiogenesis in vivo in the brain.
    Neurologia medico-chirurgica, 2012, Volume: 52, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Cell Line

2012
Human mid-trimester amniotic fluid stem cells cultured under embryonic stem cell conditions with valproic acid acquire pluripotent characteristics.
    Stem cells and development, 2013, Feb-01, Volume: 22, Issue:3

    Topics: Amniotic Fluid; Animals; Antigens, Differentiation; Cell Proliferation; Cell Shape; Cells, Cultured;

2013
Valproic acid, a histone deacetylase inhibitor, is an antagonist for oncolytic adenoviral gene therapy.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2006, Volume: 14, Issue:6

    Topics: Adenoviruses, Human; Animals; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Survival; Cyclin-

2006
[Effect of alpha-mercaptopropionylglycine (alpha-MPG) and sodium dipropylacetate (DPA) on antibody formation (IV). Tumor immunity (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1978, Volume: 74, Issue:8

    Topics: Amino Acids, Sulfur; Animals; Antibody Formation; Antineoplastic Agents; Cell Survival; Female; Lymp

1978