valproic acid has been researched along with Experimental Mammary Neoplasms in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a novel ER+ breast cancer model to study de novo and acquired tamoxifen (TAM) resistance." | 7.85 | Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model. ( Bouker, KB; Clarke, R; Cook, KL; Cruz, MI; de Assis, S; Hilakivi-Clarke, L; Hu, R; Jin, L; Nguyen, N; Wang, X; Wang, Y; Wärri, A; Wehrenberg, B; Xuan, J; Zhang, X; Zwart, A, 2017) |
| "This study explored whether valproic acid (VPA, a histone deacetylase inhibitor) could radiosensitize osteosarcoma and primary-culture tumor cells, and determined the mechanism of VPA-induced radiosensitization." | 3.85 | The Effect of VPA on Increasing Radiosensitivity in Osteosarcoma Cells and Primary-Culture Cells from Chemical Carcinogen-Induced Breast Cancer in Rats. ( Cai, Z; Feng, Z; Lim, D; Liu, G; Tian, Y; Tian, Z; Wang, H; Zhang, F, 2017) |
| "We describe a novel ER+ breast cancer model to study de novo and acquired tamoxifen (TAM) resistance." | 3.85 | Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model. ( Bouker, KB; Clarke, R; Cook, KL; Cruz, MI; de Assis, S; Hilakivi-Clarke, L; Hu, R; Jin, L; Nguyen, N; Wang, X; Wang, Y; Wärri, A; Wehrenberg, B; Xuan, J; Zhang, X; Zwart, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrade, FO | 1 |
| Nguyen, NM | 1 |
| Warri, A | 2 |
| Hilakivi-Clarke, L | 2 |
| Liu, G | 1 |
| Wang, H | 1 |
| Zhang, F | 1 |
| Tian, Y | 1 |
| Tian, Z | 1 |
| Cai, Z | 1 |
| Lim, D | 1 |
| Feng, Z | 1 |
| Bouker, KB | 1 |
| Zhang, X | 1 |
| Cook, KL | 1 |
| Jin, L | 1 |
| Zwart, A | 1 |
| Nguyen, N | 1 |
| Hu, R | 1 |
| Cruz, MI | 1 |
| de Assis, S | 1 |
| Wang, X | 1 |
| Xuan, J | 1 |
| Wang, Y | 1 |
| Wehrenberg, B | 1 |
| Clarke, R | 1 |
3 other studies available for valproic acid and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy.
Topics: Animals; Cell Transformation, Neoplastic; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Diet, | 2019 |
The Effect of VPA on Increasing Radiosensitivity in Osteosarcoma Cells and Primary-Culture Cells from Chemical Carcinogen-Induced Breast Cancer in Rats.
Topics: Animals; Cell Line, Tumor; Cells, Cultured; Chromosome Aberrations; DNA Breaks, Double-Stranded; DNA | 2017 |
Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenovirus E1A Proteins; Animals; Antineoplastic Combined Chemothe | 2017 |