Page last updated: 2024-10-26

valproic acid and Essential Tremor

valproic acid has been researched along with Essential Tremor in 3 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Essential Tremor: A relatively common disorder characterized by a fairly specific pattern of tremors which are most prominent in the upper extremities and neck, inducing titubations of the head. The tremor is usually mild, but when severe may be disabling. An autosomal dominant pattern of inheritance may occur in some families (i.e., familial tremor). (Mov Disord 1988;13(1):5-10)

Research Excerpts

ExcerptRelevanceReference
"We previously showed that nicotine evoked kinetic tremor by activating the inferior olive, which is implicated in the pathogenesis of essential tremor, via α7 nicotinic acetylcholine receptors."3.88Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents. ( Abe, K; Hashimura, M; Iha, HA; Iwai, C; Kato, M; Kawaji, S; Kawakita, K; Kunisawa, N; Ogawa, M; Ohno, Y; Shimizu, S, 2018)
"Tremor is a common movement disorder that can be induced by medications, including valproate, which is used for the treatment of epilepsy."1.62Clinical and Kinematic Features of Valproate-Induced Tremor and Differences with Essential Tremor. ( Angelini, L; Berardelli, A; Bologna, M; Cannavacciuolo, A; Colella, D; De Biase, A; Di Bonaventura, C; Giallonardo, AT; Paparella, G, 2021)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Paparella, G1
Angelini, L1
De Biase, A1
Cannavacciuolo, A1
Colella, D1
Di Bonaventura, C1
Giallonardo, AT1
Berardelli, A1
Bologna, M1
Alonso-Juarez, M1
Baizabal-Carvallo, JF1
Kunisawa, N1
Shimizu, S1
Kato, M1
Iha, HA1
Iwai, C1
Hashimura, M1
Ogawa, M1
Kawaji, S1
Kawakita, K1
Abe, K1
Ohno, Y1

Other Studies

3 other studies available for valproic acid and Essential Tremor

ArticleYear
Clinical and Kinematic Features of Valproate-Induced Tremor and Differences with Essential Tremor.
    Cerebellum (London, England), 2021, Volume: 20, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Biomechanical Phenomena; Diagnosis, Differential; E

2021
Distinguishing features between valproate-induced tremor and essential tremor.
    Acta neurologica Scandinavica, 2018, Volume: 138, Issue:2

    Topics: Adult; Aged; Diagnosis, Differential; Essential Tremor; Female; GABA Agents; Humans; Male; Middle Ag

2018
Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents.
    Journal of pharmacological sciences, 2018, Volume: 137, Issue:2

    Topics: Animals; Anticonvulsants; Antiparkinson Agents; Benzeneacetamides; Calcium Channel Blockers; Carbama

2018