Page last updated: 2024-10-26

valproic acid and Esophageal Reflux

valproic acid has been researched along with Esophageal Reflux in 4 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effect of valproic acid on transient lower oesophageal sphincter relaxation, lower oesophageal sphincter pressure and gastro-oesophageal reflux."5.10Effect of non-selective gamma-aminobutyric acid receptor stimulation on motor function of the lower oesophageal sphincter and gastro-oesophageal reflux in healthy human subjects. ( Allocca, M; Cantù, P; Carmagnola, S; Penagini, R; Savojardo, D, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantù, P1
Carmagnola, S1
Savojardo, D1
Allocca, M1
Penagini, R1
Tzovaras, G1
Tsiaoussis, J1
Athanasakis, E1
Zoras, O1
Xynos, E1
Chrysos, E1
Riikonen, R1
Chevallier, B1
Nègre, V1
Flouvat, B1
Lagardère, B1

Trials

2 trials available for valproic acid and Esophageal Reflux

ArticleYear
Effect of non-selective gamma-aminobutyric acid receptor stimulation on motor function of the lower oesophageal sphincter and gastro-oesophageal reflux in healthy human subjects.
    Alimentary pharmacology & therapeutics, 2003, Oct-01, Volume: 18, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Deglutition; Esophagogastric Junction; Female; GABA Agents; Gastroes

2003
Effect of sodium valproate on esophageal motility in healthy subjects and patients with gastroesophageal reflux.
    Scandinavian journal of gastroenterology, 2004, Volume: 39, Issue:6

    Topics: Adult; Aged; Esophagus; Female; GABA Agents; Gastroesophageal Reflux; Hernia, Hiatal; Humans; Male;

2004

Other Studies

2 other studies available for valproic acid and Esophageal Reflux

ArticleYear
Misdiagnosis of pancreatitis during valproate treatment in gastro-oesophageal reflux.
    Archives of disease in childhood, 1996, Volume: 75, Issue:4

    Topics: Adolescent; Diagnostic Errors; Gastroesophageal Reflux; Humans; Male; Pancreatitis; Valproic Acid

1996
[Valproic acid and gastroesophageal reflux in children].
    Archives francaises de pediatrie, 1989, Volume: 46, Issue:5

    Topics: Child, Preschool; Gastroesophageal Reflux; Humans; Infant; Valproic Acid

1989