valproic acid has been researched along with Erythema Multiforme in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Erythema Multiforme: A skin and mucous membrane disease characterized by an eruption of macules, papules, nodules, vesicles, and/or bullae with characteristic bull's-eye lesions usually occurring on the dorsal aspect of the hands and forearms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the association between 2 mood stabilizers (carbamazepine and valproate) and other medications (including other anticonvulsants) and the risks of erythema multiforme (EM), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) among patients with bipolar disorder." | 7.74 | The association between carbamazepine and valproate and adverse cutaneous drug reactions in patients with bipolar disorder: a nested matched case-control study. ( Chang, CJ; Chao, PF; Gau, CS; Gau, SS; Lin, YJ, 2008) |
| "This study investigated the association between 2 mood stabilizers (carbamazepine and valproate) and other medications (including other anticonvulsants) and the risks of erythema multiforme (EM), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) among patients with bipolar disorder." | 3.74 | The association between carbamazepine and valproate and adverse cutaneous drug reactions in patients with bipolar disorder: a nested matched case-control study. ( Chang, CJ; Chao, PF; Gau, CS; Gau, SS; Lin, YJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Papadopoulou, E | 1 |
| Saroglou, M | 1 |
| Ismailos, G | 1 |
| Fletsios, D | 1 |
| Tsavlis, D | 1 |
| Tryfon, S | 1 |
| Gau, SS | 1 |
| Chao, PF | 1 |
| Lin, YJ | 1 |
| Chang, CJ | 1 |
| Gau, CS | 1 |
| Kacalak-Rzepka, A | 1 |
| Kiedrowicz, M | 1 |
| Bielecka-Grzela, S | 1 |
| Ratajczak-Stefanska, V | 1 |
| Maleszka, R | 1 |
| Mikulska, D | 1 |
2 reviews available for valproic acid and Erythema Multiforme
| Article | Year |
|---|---|
Pearls for the diagnosis and possible pathophysiological mechanisms of valproic acid-induced lupus erythematosus: A literature review.
Topics: Antibodies, Antinuclear; Erythema Multiforme; Female; Humans; Lupus Erythematosus, Systemic; Male; V | 2022 |
Rowell's syndrome in the course of treatment with sodium valproate: a case report and review of the literature data.
Topics: Antipsychotic Agents; Benzodiazepines; Depressive Disorder; Drug Therapy, Combination; Erythema Mult | 2009 |
1 other study available for valproic acid and Erythema Multiforme
| Article | Year |
|---|---|
The association between carbamazepine and valproate and adverse cutaneous drug reactions in patients with bipolar disorder: a nested matched case-control study.
Topics: Acetaminophen; Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Case-Contr | 2008 |