valproic acid has been researched along with Epileptiform Neuralgia in 9 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| " For treating trigeminal neuralgia, carbamazepine had a combined number needed to treat of 2." | 6.17 | Anticonvulsant drugs for management of pain: a systematic review. ( Carroll, D; Jadad, AR; McQuay, H; Moore, A; Wiffen, P, 1995) |
| " In our article, we report two sisters, one of whom was treated with levothyroxine because of hypothyroidism." | 3.80 | Transient hypothyroidism induced by anticonvulsant agents. ( Krysiak, R; Stojko, R, 2014) |
| "The present study showed that the administration of multidrug regimens is a useful alternative in controlling trigeminal neuralgia in patients who are unable to tolerate higher doses of carbamazepine." | 3.78 | Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution. ( Ariyawardana, A; Pallegama, R; Ranasinghe, A; Sitheeque, M, 2012) |
| " On the basis of these considerations and clinical reports describing the use of these drugs, we make dosage recommendations to enable the practitioner to individualize therapeutic regimens." | 2.38 | Drugs used in the management of trigeminal neuralgia. ( Patsalos, PN; Zakrzewska, JM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krysiak, R | 1 |
| Stojko, R | 1 |
| Piovesan, EJ | 1 |
| Randunz, V | 1 |
| Utiumi, M | 1 |
| Lange, MC | 1 |
| Kowacs, PA | 1 |
| Mulinari, RA | 1 |
| Oshinsky, M | 1 |
| Vital, M | 1 |
| Sereniki, A | 1 |
| Fernandes, AF | 1 |
| e Silva, LL | 1 |
| Werneck, LC | 1 |
| Ariyawardana, A | 1 |
| Pallegama, R | 1 |
| Sitheeque, M | 1 |
| Ranasinghe, A | 1 |
| Karlov, VA | 1 |
| Savitskaia, ON | 1 |
| Peiris, JB | 1 |
| Perera, GL | 1 |
| Devendra, SV | 1 |
| Lionel, ND | 1 |
| McQuay, H | 1 |
| Carroll, D | 1 |
| Jadad, AR | 1 |
| Wiffen, P | 1 |
| Moore, A | 1 |
| Zakrzewska, JM | 1 |
| Patsalos, PN | 1 |
| Gram, L | 1 |
| Bentsen, KD | 1 |
| Grosshandler, S | 1 |
| Gray, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Erenumab as a Therapeutic Approach for the Management of Trigeminal Neuropathic Pain (TNP)[NCT05142228] | Phase 2 | 5 participants (Actual) | Interventional | 2022-04-01 | Terminated (stopped due to Low enrollment rate) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for valproic acid and Epileptiform Neuralgia
| Article | Year |
|---|---|
Anticonvulsant drugs for management of pain: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diabetic Neuropathies; Humans; Pain; Phenytoin; Treatmen | 1995 |
Drugs used in the management of trigeminal neuralgia.
Topics: Anticonvulsants; Baclofen; Carbamazepine; Clonazepam; Humans; Oxcarbazepine; Phenytoin; Trigeminal N | 1992 |
Valproate: an updated review.
Topics: Abnormalities, Drug-Induced; Brain Diseases; Chemical and Drug Induced Liver Injury; Coma; Dyskinesi | 1985 |
1 trial available for valproic acid and Epileptiform Neuralgia
| Article | Year |
|---|---|
Anticonvulsant drugs for management of pain: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diabetic Neuropathies; Humans; Pain; Phenytoin; Treatmen | 1995 |
6 other studies available for valproic acid and Epileptiform Neuralgia
| Article | Year |
|---|---|
Transient hypothyroidism induced by anticonvulsant agents.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamm | 2014 |
Influence of NMDA and non-NMDA antagonists on acute and inflammatory pain in the trigeminal territory: a placebo control study.
Topics: Animals; Exploratory Behavior; Facial Pain; Fructose; Inflammation; Male; Memantine; Motor Activity; | 2008 |
Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution.
Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Carbamazepine; Cyclohexanecarboxy | 2012 |
[Comparative effectiveness of antiepileptic preparations in the treatment of patients with trigeminal neuralgia].
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Follow-Up Studies; Humans; Morpholines; Py | 1980 |
Sodium valproate in trigeminal neuralgia.
Topics: Aged; Anticonvulsants; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Trigeminal Neur | 1980 |
Successful therapy of postherpetic neuralgia of the trigeminal nerve.
Topics: Combined Modality Therapy; Diflunisal; Doxepin; Female; Herpes Zoster; Humans; Middle Aged; Physical | 1985 |