valproic acid has been researched along with Epilepsy, Temporal Lobe in 110 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The anxiety induced by pilocarpine was also significantly (P < 0." | 8.12 | Anticonvulsant effects of Cymbopogon giganteus extracts with possible effects on fully kindled seizures and anxiety in experimental rodent model of mesio-temporal epilepsy induced by pilocarpine. ( Bum, EN; Kouemou Emegam, N; Neteydji, S; Pale, S; Taiwe, GS, 2022) |
| "Of 88 patients with intractable epilepsy, 60 have been treated with clonazepam for up to three years and 60 have been treated with sodium valproate for up to 18 months." | 7.65 | Sodium valproate and clonazepam in the treatment of intractable epilepsy. ( Anthony, M; Lance, JW, 1977) |
| "We observed two patients who developed coma following administration of valproate in dosages of 32 to 40 mg/kg per day." | 5.28 | Valproate-induced coma with ketosis and carnitine insufficiency. ( Bohan, TP; Lin, SN; Triggs, WJ; Willmore, LJ, 1990) |
| "QUIN seizures showed particular sensitivity to carbamazepine (5 mg/kg) but were resistant to diphenylhydantoin unless a relatively high dose was used (100 mg/kg)." | 5.27 | Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1986) |
| "Eighty-eight patients with the onset of epilepsy in adult life were randomly allocated to treatment with sodium valproate (600 mg/day), or phenytoin (300 mg/day), and followed up for at least 12 months." | 5.05 | A comparison of phenytoin and valproate in previously untreated adult epileptic patients. ( Chadwick, DW; Rawlins, MD; Turnbull, DM; Weightman, D, 1982) |
| " The anxiety induced by pilocarpine was also significantly (P < 0." | 4.12 | Anticonvulsant effects of Cymbopogon giganteus extracts with possible effects on fully kindled seizures and anxiety in experimental rodent model of mesio-temporal epilepsy induced by pilocarpine. ( Bum, EN; Kouemou Emegam, N; Neteydji, S; Pale, S; Taiwe, GS, 2022) |
| " We previously showed that tolerance to levetiracetam (LEV) developed within 4 days after the start of the treatment in a rat model for spontaneous seizures after electrically induced status epilepticus." | 3.76 | Improved seizure control by alternating therapy of levetiracetam and valproate in epileptic rats. ( Edelbroek, PM; Gorter, JA; van Vliet, EA, 2010) |
| " The second patient complained of impotence after a rash while taking phenytoin and carbamazepine." | 3.70 | Improved sexual function in three men taking lamotrigine for epilepsy. ( Carwile, ST; Husain, AM; Miller, PP; Radtke, RA, 2000) |
| " Five years later she developed myasthenia gravis, and phenytoin was replaced by valproic acid and phenobarbital." | 3.68 | Epilepsy, myasthenia gravis, and effect of plasmapheresis on antiepileptic drug concentrations. ( Jenkins, DC; Lai, CW; Leppik, IE; Sood, P, 1990) |
| "Of 88 patients with intractable epilepsy, 60 have been treated with clonazepam for up to three years and 60 have been treated with sodium valproate for up to 18 months." | 3.65 | Sodium valproate and clonazepam in the treatment of intractable epilepsy. ( Anthony, M; Lance, JW, 1977) |
| "We review the various forms of partial epilepsy that appear in childhood and adolescence, emphasizing the most common forms." | 2.39 | [The diagnosis and treatment of partial epilepsy in childhood and adolescence]. ( Martínez Bermejo, Z; Pascual-Castroviejo, I, 1996) |
| "Gentamicin (GM) is an aminoglycoside antibiotic used to treat several types of bacterial infections." | 1.48 | Anticonvulsant effect of gentamicin on the seizures induced by kainic acid. ( Ji, Y; Jiang, N; Kuang, P; Lao, W; Lin, W; Wang, Z; Yin, T; Zhao, Y; Zhu, H, 2018) |
| "In a first step, we examined anti-seizure effects of 6 AEDs on spontaneous recurrent focal electrographic seizures and secondarily generalized convulsive seizures in epileptic mice, showing that the focal nonconvulsive seizures were resistant to carbamazepine and phenytoin, whereas valproate and levetiracetam exerted moderate and phenobarbital and diazepam marked anti-seizure effects." | 1.42 | Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice. ( Bankstahl, M; Klein, S; Löscher, W, 2015) |
| " However, this is the first case of VPA-induced hearing loss that was tested and confirmed with a VPA rechallenge, supported by serial audiometry and pharmacokinetic modelling." | 1.40 | Valproate-induced reversible sensorineural hearing loss: a case report with serial audiometry and pharmacokinetic modelling during a valproate rechallenge. ( Bakar, MZ; Lim, KS; Lo, YL; Tan, CT; Yeap, LL, 2014) |
| "Headache is a frequent clinical symptom of lateralizing value, which may share common pathophysiology with epileptogenesis among MTLE-HS patients." | 1.37 | Hippocampal sclerosis and ipsilateral headache among mesial temporal lobe epilepsy patients. ( Bastos, A; Claudino, LS; Guarnieri, R; Lin, K; Nunes, JC; Queiroz, LP; Walz, R; Zakon, DB, 2011) |
| "Some authors suggest that most impact seizures are non-epileptic in origin and hence coined the term "concussive convulsions" for benign impact seizures." | 1.37 | [Concussive convulsions: seizure or no seizure?]. ( Burghaus, L; Elger, CE; Fink, GR; Nass, RD, 2011) |
| "Carbamazepine was progressively withdrawn and the patient was progressively switched to zonisamide." | 1.35 | Wicket spikes misinterpreted as focal abnormalities in idiopathic generalized epilepsy with prescription of carbamazepine leading to paradoxical aggravation. ( Coubes, P; Crespel, A; Gélisse, P; Genton, P; Velizarova, R, 2009) |
| "This means that seizures do not arise de novo in the seizure focus." | 1.34 | Temporal lobe epilepsy is a disease of faulty neuronal resonators rather than oscillators, and all seizures are provoked, usually by stress. ( Eggers, AE, 2007) |
| "Temporal lobe epilepsy is a partial epileptic disorder in which mesial structures are responsible for the principal ictal symptoms." | 1.32 | [Yawning and temporal lobe epilepsy]. ( de Aguirre, MI; Finkielman, S; Muchnik, S; Semeniuk, G, 2003) |
| "One hundred seventy-eight men had focal epilepsy (117 of these had temporal lobe epilepsy [TLE]) and 22 idiopathic generalized epilepsy (IGE)." | 1.32 | Epilepsy syndrome, focus location, and treatment choice affect testicular function in men with epilepsy. ( Bauer, J; Blumenthal, S; Reuber, M; Stoffel-Wagner, B, 2004) |
| "Carbamazepine was the most commonly used AED in 71." | 1.31 | Antiepileptic drug withdrawal in patients with temporal lobe epilepsy undergoing presurgical video-EEG monitoring. ( Chen, C; Guo, YC; Kwan, SY; Liu, LT; Shih, YH; Yen, DJ; Yiu, CH; Yu, HY, 2001) |
| "A total of 21 patients with juvenile myoclonic epilepsy (JME) and 21 with temporal lobe epilepsy (TLE) were included; 18 patients were treated with carbamazepine (CBZ), 16 with valproate (VPA) and seven with phenytoin (PHT)." | 1.30 | Heart rate variability in patients with epilepsy. ( Ericson, M; Ihrman, C; Lindblad, LE; Tomson, T, 1998) |
| "We compared the estimated surgical blood loss and the estimated change in red blood cell (RBC) volume between groups by unpaired t tests." | 1.29 | Preoperative valproate administration does not increase blood loss during temporal lobectomy. ( Barbaro, NM; Laxer, KD; Rampil, IJ; Ward, MM, 1996) |
| "We observed two patients who developed coma following administration of valproate in dosages of 32 to 40 mg/kg per day." | 1.28 | Valproate-induced coma with ketosis and carnitine insufficiency. ( Bohan, TP; Lin, SN; Triggs, WJ; Willmore, LJ, 1990) |
| "These findings represent VPA-induced sensorineural hearing loss, possibly in preexisting presbycusis." | 1.28 | Sensorineural hearing loss: a reversible effect of valproic acid. ( Armon, C; Brown, E; Carwile, S; Miller, P; Shin, C, 1990) |
| " Toxic effects were generally mild." | 1.27 | Valproic acid therapy for complex partial seizures. Its efficacy and toxic effects. ( Albright, P; Bruni, J, 1983) |
| "QUIN seizures showed particular sensitivity to carbamazepine (5 mg/kg) but were resistant to diphenylhydantoin unless a relatively high dose was used (100 mg/kg)." | 1.27 | Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1986) |
| "Phenytoin and Valproate was administered." | 1.26 | [Coincidence of epilepsy and psychosis in a 16-year old female patient (author's transl)]. ( Rentz, R, 1980) |
| "28 children with Petit mal epilepsy were treated with valproic acid either as drug of primary choice or because of resistance to other antiepileptic drugs." | 1.26 | [Valproic acid -- clinical efficiency and serum concentration in the treatment of petit mal epilepsy in childhood (author's transl)]. ( Fritsch, G; Gleispach, H; Haidvogl, M; Ladurner, G, 1981) |
| " The signs and symptoms did not directly correlate with VPA dosage and the arterial ammonium levels did not correlate with serum VPA concentrations." | 1.26 | Sodium valproate-induced hyperammonemia without clinical hepatic dysfunction. ( Beckner, RR; Marini, AM; Passarelli, C; Wagle, W; Zaret, BS, 1982) |
| " In rather short time reliable information concerning indication, compatibility and dosage can be received." | 1.26 | [Austrian complex-study on dipropylacetate. Pediatric experiences]. ( Groh, Ch; Rosenmayr, FW, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (40.91) | 18.7374 |
| 1990's | 26 (23.64) | 18.2507 |
| 2000's | 17 (15.45) | 29.6817 |
| 2010's | 17 (15.45) | 24.3611 |
| 2020's | 5 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Pale, S | 1 |
| Neteydji, S | 1 |
| Taiwe, GS | 1 |
| Kouemou Emegam, N | 1 |
| Bum, EN | 1 |
| Li, J | 1 |
| Sha, L | 1 |
| Xu, Q | 1 |
| Jung, I | 1 |
| Shin, JH | 1 |
| Kim, J | 1 |
| Xu, CL | 1 |
| Nao, JZ | 1 |
| Shen, YJ | 1 |
| Gong, YW | 1 |
| Tan, B | 1 |
| Zhang, S | 1 |
| Shen, KX | 1 |
| Sun, CR | 1 |
| Wang, Y | 1 |
| Chen, Z | 1 |
| Kavaye Kandeda, A | 1 |
| Okomolo Moto, FC | 1 |
| Mbomo Ayissi, RE | 1 |
| Omam Omam, JP | 1 |
| Ojong, L | 1 |
| Ngo Bum, E | 1 |
| Agah, E | 1 |
| Asgari-Rad, N | 1 |
| Ahmadi, M | 1 |
| Tafakhori, A | 1 |
| Aghamollaii, V | 1 |
| Androsova, G | 1 |
| Krause, R | 1 |
| Borghei, M | 1 |
| Wassenaar, M | 1 |
| Auce, P | 1 |
| Avbersek, A | 1 |
| Becker, F | 1 |
| Berghuis, B | 1 |
| Campbell, E | 1 |
| Coppola, A | 1 |
| Francis, B | 1 |
| Wolking, S | 1 |
| Cavalleri, GL | 1 |
| Craig, J | 1 |
| Delanty, N | 1 |
| Koeleman, BPC | 1 |
| Kunz, WS | 1 |
| Lerche, H | 1 |
| Marson, AG | 1 |
| Sander, JW | 1 |
| Sills, GJ | 1 |
| Striano, P | 1 |
| Zara, F | 1 |
| Sisodiya, SM | 1 |
| Depondt, C | 1 |
| Williams, RSB | 1 |
| Bate, C | 1 |
| Zhao, Y | 1 |
| Wang, Z | 1 |
| Lao, W | 1 |
| Kuang, P | 1 |
| Jiang, N | 1 |
| Yin, T | 1 |
| Lin, W | 1 |
| Zhu, H | 1 |
| Ji, Y | 1 |
| Ganjkhani, M | 1 |
| Nourozi, S | 1 |
| Bigonah, R | 1 |
| Rostami, A | 1 |
| Shokri, S | 1 |
| Yeap, LL | 1 |
| Lim, KS | 1 |
| Lo, YL | 1 |
| Bakar, MZ | 1 |
| Tan, CT | 1 |
| Sundin, JR | 1 |
| Øksengård, AR | 1 |
| Røste, LS | 1 |
| Svendsen, J | 1 |
| Ihle-Hansen, H | 1 |
| Klein, S | 1 |
| Bankstahl, M | 1 |
| Löscher, W | 2 |
| Wen, B | 1 |
| Qian, H | 1 |
| Feng, J | 1 |
| Ge, RJ | 1 |
| Xu, X | 1 |
| Cui, ZQ | 1 |
| Zhu, RY | 1 |
| Pan, LS | 1 |
| Lin, ZP | 1 |
| Wang, JH | 1 |
| Barker-Haliski, ML | 2 |
| Dahle, EJ | 2 |
| Heck, TD | 2 |
| Pruess, TH | 2 |
| Vanegas, F | 2 |
| Wilcox, KS | 2 |
| White, HS | 2 |
| van Vliet, EA | 1 |
| Edelbroek, PM | 1 |
| Gorter, JA | 1 |
| Crespel, A | 1 |
| Velizarova, R | 1 |
| Genton, P | 1 |
| Coubes, P | 1 |
| Gélisse, P | 1 |
| Boldyreva, SR | 1 |
| Ermakov, AIu | 1 |
| Wu, L | 2 |
| Peng, J | 1 |
| Wei, C | 1 |
| Liu, G | 1 |
| Wang, G | 1 |
| Li, K | 1 |
| Yin, F | 1 |
| Smith, AP | 1 |
| Sani, S | 1 |
| Kanner, AM | 1 |
| Stoub, T | 1 |
| Morrin, M | 1 |
| Palac, S | 1 |
| Bergen, DC | 1 |
| Balabonov, A | 1 |
| Smith, M | 1 |
| Whisler, WW | 1 |
| Byrne, RW | 1 |
| Nunes, JC | 1 |
| Zakon, DB | 1 |
| Claudino, LS | 1 |
| Guarnieri, R | 1 |
| Bastos, A | 1 |
| Queiroz, LP | 1 |
| Walz, R | 1 |
| Lin, K | 1 |
| Nass, RD | 1 |
| Elger, CE | 1 |
| Fink, GR | 1 |
| Burghaus, L | 1 |
| Klitgaard, H | 1 |
| Matagne, A | 1 |
| Grimee, R | 1 |
| Vanneste-Goemaere, J | 1 |
| Margineanu, DG | 1 |
| Shahar, E | 1 |
| Barak, S | 1 |
| Muchnik, S | 1 |
| Finkielman, S | 1 |
| Semeniuk, G | 1 |
| de Aguirre, MI | 1 |
| Pohlmann-Eden, B | 1 |
| Peters, CN | 1 |
| Wennberg, R | 1 |
| Dempfle, CE | 1 |
| Bauer, J | 2 |
| Blumenthal, S | 1 |
| Reuber, M | 1 |
| Stoffel-Wagner, B | 1 |
| Wang-Tilz, Y | 1 |
| Tilz, C | 1 |
| Wang, B | 1 |
| Tilz, GP | 1 |
| Stefan, H | 1 |
| Eggers, AE | 1 |
| Alqahtani, S | 1 |
| Federico, P | 1 |
| Myers, RP | 1 |
| Pupko, HA | 1 |
| Garcia-Merino, JA | 1 |
| Lopez-Lozano, JJ | 1 |
| Bruni, J | 3 |
| Albright, P | 1 |
| Schmidt, D | 2 |
| Rowan, AJ | 1 |
| Warter, JM | 2 |
| Marescaux, C | 2 |
| Rumbach, L | 2 |
| Micheletti, G | 2 |
| Chabrier, G | 1 |
| Koehl, C | 2 |
| Imler, M | 1 |
| Collard, M | 2 |
| Dulac, O | 1 |
| Arthuis, M | 1 |
| Wilder, BJ | 1 |
| Bauman, AW | 1 |
| Willmore, LJ | 2 |
| Koch-Weser, J | 1 |
| Browne, TR | 1 |
| Leary, PM | 1 |
| Morris, S | 1 |
| Rentz, R | 1 |
| Rohmer, F | 1 |
| Kurtz, D | 1 |
| Fritsch, G | 1 |
| Haidvogl, M | 1 |
| Gleispach, H | 1 |
| Ladurner, G | 1 |
| Zaret, BS | 1 |
| Beckner, RR | 1 |
| Marini, AM | 1 |
| Wagle, W | 1 |
| Passarelli, C | 1 |
| Turnbull, DM | 1 |
| Rawlins, MD | 1 |
| Weightman, D | 1 |
| Chadwick, DW | 1 |
| Boldyrev, AI | 1 |
| van Rijckevorsel, K | 1 |
| Saussu, F | 1 |
| de Barsy, T | 1 |
| Puryear, LJ | 1 |
| Kunik, ME | 1 |
| Molinari, V | 1 |
| Workman, RH | 1 |
| Couper, J | 1 |
| Wieser, HG | 1 |
| Ward, MM | 1 |
| Barbaro, NM | 1 |
| Laxer, KD | 1 |
| Rampil, IJ | 1 |
| Martínez Bermejo, Z | 1 |
| Pascual-Castroviejo, I | 1 |
| Nezu, A | 1 |
| Kimura, S | 1 |
| Ohtsuki, N | 1 |
| Tanaka, M | 1 |
| Tomson, T | 1 |
| Ericson, M | 1 |
| Ihrman, C | 1 |
| Lindblad, LE | 1 |
| Gil-Fernández, JJ | 1 |
| Morimoto, K | 1 |
| Sato, H | 1 |
| Yamamoto, Y | 1 |
| Watanabe, T | 1 |
| Suwaki, H | 1 |
| Baldassano, CF | 1 |
| Ghaemi, SN | 1 |
| Arita, K | 1 |
| Kurisu, K | 1 |
| Iida, K | 1 |
| Hanaya, R | 1 |
| Akimitsu, T | 1 |
| Hibino, S | 1 |
| Pant, B | 1 |
| Hamasaki, M | 1 |
| Shinagawa, S | 1 |
| Arroyo, S | 1 |
| Rumiá, J | 1 |
| Martínez, I | 1 |
| Ribalta, T | 1 |
| García-Herrero, D | 1 |
| Fernández-Torre, JL | 1 |
| Barrasa, J | 1 |
| Calleja, J | 1 |
| Pascual, J | 1 |
| Lehmann, H | 1 |
| Behl, B | 1 |
| Seemann, D | 1 |
| Teschendorf, HJ | 1 |
| Hofmann, HP | 1 |
| Lubisch, W | 1 |
| Höger, T | 1 |
| Lemaire, HG | 1 |
| Gross, G | 1 |
| Husain, AM | 1 |
| Carwile, ST | 1 |
| Miller, PP | 1 |
| Radtke, RA | 1 |
| Lamusuo, S | 1 |
| Pitkänen, A | 1 |
| Jutila, L | 1 |
| Ylinen, A | 1 |
| Partanen, K | 1 |
| Kälviäinen, R | 1 |
| Ruottinen, HM | 1 |
| Oikonen, V | 1 |
| Någren, K | 1 |
| Lehikoinen, P | 1 |
| Vapalahti, M | 1 |
| Vainio, P | 1 |
| Rinne, JO | 1 |
| Bellman, M | 1 |
| Pathan, AH | 1 |
| Sinclair, L | 1 |
| Maton, B | 1 |
| Picard, F | 1 |
| Njamshi, A | 1 |
| Roth, S | 1 |
| Slosman, D | 1 |
| Sztajzel, R | 1 |
| Jallon, P | 1 |
| Landis, T | 1 |
| Theodore, WH | 1 |
| Yen, DJ | 1 |
| Chen, C | 1 |
| Shih, YH | 1 |
| Guo, YC | 1 |
| Liu, LT | 1 |
| Yu, HY | 1 |
| Kwan, SY | 1 |
| Yiu, CH | 1 |
| Tassinari, CA | 1 |
| Roger, J | 1 |
| Sackellares, JC | 1 |
| Lee, SI | 1 |
| Dreifuss, FE | 1 |
| Lance, JW | 2 |
| Anthony, M | 2 |
| Pinder, RM | 1 |
| Brogden, RN | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Hosokawa, K | 1 |
| Kugoh, T | 1 |
| Otsuki, S | 1 |
| Boucharlat, PJ | 1 |
| Ratel, M | 1 |
| Maitre, A | 1 |
| Ledru, J | 1 |
| Simon, D | 1 |
| Penry, JK | 1 |
| Haigh, D | 1 |
| Forsythe, WI | 1 |
| Groh, Ch | 1 |
| Rosenmayr, FW | 1 |
| Hassan, MN | 1 |
| Laljee, HC | 1 |
| Parsonage, MJ | 1 |
| Malek, F | 1 |
| Mamoli, B | 1 |
| Pateisky, K | 1 |
| Clarke, BM | 1 |
| Upton, A | 1 |
| Griffin, H | 1 |
| Hudoba, P | 1 |
| Takahashi, K | 1 |
| Saito, M | 1 |
| Kyo, K | 1 |
| Gomibuchi, K | 1 |
| Niijima, S | 1 |
| Tada, H | 1 |
| Honda, T | 1 |
| Sato, Y | 1 |
| Takahashi, H | 1 |
| Ohtsuka, C | 1 |
| Papazian, O | 1 |
| Lai, CW | 1 |
| Leppik, IE | 1 |
| Jenkins, DC | 1 |
| Sood, P | 1 |
| Altshuler, LL | 1 |
| Devinsky, O | 1 |
| Post, RM | 1 |
| Theodore, W | 1 |
| Triggs, WJ | 1 |
| Bohan, TP | 1 |
| Lin, SN | 1 |
| Amano, R | 1 |
| Mizukawa, M | 1 |
| Ohtsuka, Y | 1 |
| Ohtahara, S | 1 |
| Jongsma, MJ | 1 |
| Snijders, CJ | 1 |
| Armon, C | 1 |
| Brown, E | 1 |
| Carwile, S | 1 |
| Miller, P | 1 |
| Shin, C | 1 |
| Giakas, WJ | 1 |
| Seibyl, JP | 1 |
| Mazure, CM | 1 |
| Upton, AR | 1 |
| Amin, I | 1 |
| Garnett, S | 1 |
| Springman, M | 1 |
| Nahmias, C | 1 |
| Cooper, IS | 1 |
| Rascol, O | 1 |
| Squalli, A | 1 |
| Montastruc, JL | 1 |
| Garat, A | 1 |
| Houin, G | 1 |
| Lachau, S | 1 |
| Tor, J | 1 |
| Blehaut, H | 1 |
| Rascol, A | 1 |
| Tachibana, N | 1 |
| Sugita, Y | 1 |
| Teshima, Y | 1 |
| Hishikawa, Y | 1 |
| Hara, H | 1 |
| Fukuyama, Y | 1 |
| McKee, RJ | 1 |
| Larkin, JG | 1 |
| Brodie, MJ | 1 |
| Vezzani, A | 1 |
| Wu, HQ | 1 |
| Tullii, M | 1 |
| Samanin, R | 1 |
| Klepel, H | 1 |
| Koch, RD | 1 |
| Tzenow, H | 1 |
| Bova, VE | 1 |
| Larrieu, JL | 2 |
| Lagueny, A | 2 |
| Ferrer, X | 1 |
| Julien, J | 2 |
| Goulden, KJ | 1 |
| Dooley, JM | 1 |
| Camfield, PR | 1 |
| Fraser, AD | 1 |
| Ishikawa, T | 1 |
| Ogino, C | 1 |
| Furuyama, M | 1 |
| Kanayama, M | 1 |
| Awaya, A | 1 |
| Yamaguchi, A | 1 |
| Gupta, AK | 2 |
| Jacome, DE | 1 |
| Suarez, M | 1 |
| Jeavons, PM | 1 |
| Vining, EP | 1 |
| Freeman, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Monitoring of Seizures, EEG and Serum Antiepileptic Drug Concentrations in Patients With Uncontrolled Epilepsy[NCT00001149] | 900 participants | Observational | 1975-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for valproic acid and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; E | 1983 |
Drug therapy: Valproic acid.
Topics: Adult; Alopecia; Behavior; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chil | 1980 |
[The diagnosis and treatment of partial epilepsy in childhood and adolescence].
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epile | 1996 |
PET: cerebral blood flow and glucose metabolism--pathophysiology and drug effects.
Topics: Anticonvulsants; Cerebrovascular Circulation; Epilepsy, Temporal Lobe; Glucose; Humans; Metabolic Cl | 2000 |
Epilepsy therapy: issues for women and men.
Topics: Anticonvulsants; Congenital Abnormalities; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Infert | 2001 |
Sodium valproate: a review of its pharmacological properties and therapeutic efficacy in epilepsy.
Topics: Administration, Oral; Adult; Animals; Anticonvulsants; Behavior; Blood Platelets; Child; Clinical Tr | 1977 |
Sodium di-N-propylacetate (DPA) in the treatment of epilepsy. A review.
Topics: Adolescent; Adult; Age Factors; Animals; Cerebral Cortex; Child; Child, Preschool; Drug Evaluation; | 1975 |
8 trials available for valproic acid and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Clinical efficacy and long-term effects of valproic acid therapy on spike-and-wave discharges.
Topics: Clinical Trials as Topic; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Absence | 1980 |
Drug therapy: Valproic acid.
Topics: Adult; Alopecia; Behavior; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chil | 1980 |
A comparison of phenytoin and valproate in previously untreated adult epileptic patients.
Topics: Adolescent; Adult; Age Factors; Aged; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Humans | 1982 |
[Comparison of valproate level in human plasma, cerebrospinal fluid and brain tissue following administration of various preparations of valproate and valpromide].
Topics: Adolescent; Adult; Anticonvulsants; Blood-Brain Barrier; Brain; Brain Chemistry; Epilepsy, Temporal | 1994 |
Transcranial magnetic stimulation in benign childhood epilepsy with centro-temporal spikes.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Temporal Lobe; Female; Humans; Magnetoencephalography; | 1997 |
[11 C]Flumazenil binding in the medial temporal lobe in patients with temporal lobe epilepsy: correlation with hippocampal MR volumetry, T2 relaxometry, and neuropathology.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Epilepsy, Temporal Lobe; Female; Flumazenil; GA | 2000 |
Sodium valproate: a review of its pharmacological properties and therapeutic efficacy in epilepsy.
Topics: Administration, Oral; Adult; Animals; Anticonvulsants; Behavior; Blood Platelets; Child; Clinical Tr | 1977 |
A pilot study of stiripentol, a new anticonvulsant drug, in complex partial seizures uncontrolled by carbamazepine.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Dioxolanes; Dioxoles; Drug Sy | 1989 |
97 other studies available for valproic acid and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Anticonvulsant effects of Cymbopogon giganteus extracts with possible effects on fully kindled seizures and anxiety in experimental rodent model of mesio-temporal epilepsy induced by pilocarpine.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Cymbopogon; Disease Models, Animal; Dose-Res | 2022 |
Long-term outcomes of classic and novel anti-seizure medication in a kainate-induced model of chronic epilepsy.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; Epilepsy, Temporal Lobe; Kainic Acid; Mice; Valpr | 2023 |
Gaze-evoked nystagmus associated with valproic acid-induced lamotrigine toxicity.
Topics: Adult; Anticonvulsants; Epilepsy, Temporal Lobe; Female; Humans; Lamotrigine; Nystagmus, Pathologic; | 2020 |
Long-term music adjuvant therapy enhances the efficacy of sub-dose antiepileptic drugs in temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Combined Modality Therapy; Disease Models, Animal; Electroencephalography; | 2022 |
Pergularia daemia hydro-ethanolic extract protects against pentylenetetrazole kindling-induced seizures, oxidative stress, and neuroinflammation in mice.
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Antioxidants; Apocynaceae; Cameroon; Cognitive D | 2021 |
Evaluating executive function in patients with temporal lobe epilepsy using the frontal assessment battery.
Topics: Adolescent; Adult; Anticonvulsants; Cognition Disorders; Epilepsy, Temporal Lobe; Executive Function | 2017 |
Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Ataxia; Benzodiazepines; Carbamazepine; Clobazam; | 2017 |
Valproic acid and its congener propylisopropylacetic acid reduced the amount of soluble amyloid-β oligomers released from 7PA2 cells.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Membrane Structures; Cells, Cul | 2018 |
Anticonvulsant effect of gentamicin on the seizures induced by kainic acid.
Topics: Analysis of Variance; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, | 2018 |
Ameliorating impacts of ginseng on the apoptosis of spermatogenic cells and sperm quality in temporal lobe epilepsy rat model treated with valproate.
Topics: Animals; Anticonvulsants; Apoptosis; Disease Models, Animal; Epilepsy, Temporal Lobe; Humans; Infert | 2019 |
Valproate-induced reversible sensorineural hearing loss: a case report with serial audiometry and pharmacokinetic modelling during a valproate rechallenge.
Topics: Adult; Anticonvulsants; Audiometry; Epilepsy, Temporal Lobe; Evoked Potentials, Auditory, Brain Stem | 2014 |
[Woman in her 70s with rapidly increasing cognitive impairment].
Topics: Aged; Anti-Bacterial Agents; Anticonvulsants; Borrelia burgdorferi; Ceftriaxone; Cognition Disorders | 2014 |
Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Resistance; Electrod | 2015 |
A portion of inhibitory neurons in human temporal lobe epilepsy are functionally upregulated: an endogenous mechanism for seizure termination.
Topics: Anticonvulsants; Biophysics; Biotin; Brain; Computer Simulation; Down-Regulation; Electroencephalogr | 2015 |
Evaluating an etiologically relevant platform for therapy development for temporal lobe epilepsy: effects of carbamazepine and valproic acid on acute seizures and chronic behavioral comorbidities in the Theiler's murine encephalomyelitis virus mouse model
Topics: Animals; Anticonvulsants; Anxiety; Behavior, Animal; Carbamazepine; Cardiovirus Infections; Comorbid | 2015 |
Acute treatment with minocycline, but not valproic acid, improves long-term behavioral outcomes in the Theiler's virus model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Anxiety Disorders; Behavior, Animal; Body Weight; Chi-Square Distribution; | 2016 |
Improved seizure control by alternating therapy of levetiracetam and valproate in epileptic rats.
Topics: Animals; Anticonvulsants; Dentate Gyrus; Disease Models, Animal; Drug Administration Schedule; Drug | 2010 |
Wicket spikes misinterpreted as focal abnormalities in idiopathic generalized epilepsy with prescription of carbamazepine leading to paradoxical aggravation.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Clonazepam; Diagnostic Errors; Drug Thera | 2009 |
[Efficacy of carbamazepine, valproate and topiramate in the treatment of medial temporal epilepsy in children].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy, Temporal Lobe; Female | 2010 |
Characterization, using comparative proteomics, of differentially expressed proteins in the hippocampus of the mesial temporal lobe of epileptic rats following treatment with valproate.
Topics: Adolescent; Adult; Animals; Child; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Ep | 2011 |
Medically intractable temporal lobe epilepsy in patients with normal MRI: surgical outcome in twenty-one consecutive patients.
Topics: Adult; Age of Onset; Anticonvulsants; Cross-Sectional Studies; Educational Status; Electroencephalog | 2011 |
Hippocampal sclerosis and ipsilateral headache among mesial temporal lobe epilepsy patients.
Topics: Adult; Age of Onset; Anticonvulsants; Cross-Sectional Studies; Educational Status; Electroencephalog | 2011 |
[Concussive convulsions: seizure or no seizure?].
Topics: Adult; Anticonvulsants; Brain; Brain Concussion; Electroencephalography; Epilepsy, Post-Traumatic; E | 2011 |
Electrophysiological, neurochemical and regional effects of levetiracetam in the rat pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Aspartic Acid; Clonazepam; Electroencephalography; Epilepsy, Temporal Lobe | 2003 |
Favorable outcome of epileptic blindness in children.
Topics: Acute Disease; Adolescent; Anticonvulsants; Blindness, Cortical; Carbamazepine; Child; Electroenceph | 2003 |
[Yawning and temporal lobe epilepsy].
Topics: Adolescent; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy, Temporal Lobe; Female | 2003 |
Valproate induces reversible factor XIII deficiency with risk of perioperative bleeding.
Topics: Adult; Amygdala; Anticonvulsants; Epilepsy, Temporal Lobe; Factor XIII; Hippocampus; Humans; Intracr | 2003 |
Epilepsy syndrome, focus location, and treatment choice affect testicular function in men with epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epileps | 2004 |
Influence of lamotrigine and topiramate on MDR1 expression in difficult-to-treat temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazep | 2006 |
Temporal lobe epilepsy is a disease of faulty neuronal resonators rather than oscillators, and all seizures are provoked, usually by stress.
Topics: Anticonvulsants; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; Hippocampus; Humans; Models, Neuro | 2007 |
A case of valproate-induced hyperammonemic encephalopathy: look beyond the liver.
Topics: Adolescent; Anticonvulsants; Diagnosis, Differential; Electroencephalography; Epilepsy, Temporal Lob | 2007 |
Possible new clinical sign of hyperammonemia.
Topics: Adolescent; Anticonvulsants; Diagnosis, Differential; Electroencephalography; Epilepsy, Temporal Lob | 2008 |
Risks of valproate in porphyria.
Topics: Acute Disease; Adult; Epilepsy, Temporal Lobe; Female; Humans; Porphyrias; Valproic Acid | 1980 |
Valproic acid therapy for complex partial seizures. Its efficacy and toxic effects.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Valp | 1983 |
Reduction of two-drug therapy in intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Therapy, Combination; Epilepsy, Temporal Lob | 1983 |
[Role of hyperammonemia in stuporous states induced by sodium valproate].
Topics: Adult; Ammonia; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Female; Glutamine; Humans; U | 1983 |
Open trials with valproate in epilepsy.
Topics: Drug Therapy; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Temporal Lobe; Humans; Valproic Acid | 1984 |
Clinical experience with sodium valproate in children.
Topics: Adolescent; Child; Child, Preschool; Drug Evaluation; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Abs | 1980 |
[Coincidence of epilepsy and psychosis in a 16-year old female patient (author's transl)].
Topics: Adolescent; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Phenytoin; Valproic Aci | 1980 |
Valproic acid and plasma levels of primidone and derived phenobarbital.
Topics: Adult; Drug Interactions; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Female; Humans; Kineti | 1981 |
[Stuporous states during treatment with sodium valproate. Pathogenetic hypotheses].
Topics: Adult; Aged; Anticonvulsants; Drug Synergism; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle | 1981 |
[Valproic acid -- clinical efficiency and serum concentration in the treatment of petit mal epilepsy in childhood (author's transl)].
Topics: Child; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Absence; Epilepsy, Tempor | 1981 |
Sodium valproate-induced hyperammonemia without clinical hepatic dysfunction.
Topics: Adult; Ammonia; Brain Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electro | 1982 |
[Clinical evaluation of certain modern antiepileptic preparations].
Topics: Anticonvulsants; Automatism; Carbamazepine; Child; Clonazepam; Diencephalon; Epilepsy; Epilepsy, Abs | 1982 |
Two antiepileptic drugs for intractable epilepsy with complex-partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epileps | 1982 |
Bradycardia, an epileptic ictal manifestation.
Topics: Adult; Anticonvulsants; Bradycardia; Electrocardiography; Electroencephalography; Epilepsy; Epilepsy | 1995 |
Psychiatric manifestations of temporal lobe epilepsy in older adults.
Topics: Aged; Dementia; Depressive Disorder; Diagnosis, Differential; Electroencephalography; Epilepsy, Temp | 1995 |
Unilateral musical hallucinations and all that jazz.
Topics: Aged; Auditory Perceptual Disorders; Cerebrovascular Disorders; Dominance, Cerebral; Drug Therapy, C | 1994 |
Preoperative valproate administration does not increase blood loss during temporal lobectomy.
Topics: Adult; Anticonvulsants; Blood Loss, Surgical; Blood Transfusion; Epilepsy, Temporal Lobe; Erythrocyt | 1996 |
Heart rate variability in patients with epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Epilepsy, Temporal Lobe; Female; Heart | 1998 |
Analysis of surgical blood loss and number of blood transfusions after temporal lobe resection performed in adults with epilepsy receiving valproate (VPA) in the immediate preoperative period.
Topics: Adolescent; Adult; Aged; Bleeding Time; Blood Loss, Surgical; Blood Transfusion; Epilepsy, Temporal | 1997 |
Antiepileptic effects of tiagabine, a selective GABA uptake inhibitor, in the rat kindling model of temporal lobe epilepsy.
Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Dru | 1997 |
Generalized edema with risperidone: divalproex sodium treatment.
Topics: Adult; Bipolar Disorder; Comorbidity; Edema; Epilepsy, Temporal Lobe; Humans; Male; Risperidone; Val | 1996 |
Subsidence of seizure induced by stereotactic radiation in a patient with hypothalamic hamartoma. Case report.
Topics: Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, To | 1998 |
[Drug-resistant epilepsy].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Calcinosis; Carbamazepine; Diagnosis, Differential; Drug Re | 1998 |
Abdominal epilepsy in an adolescent with bilateral perisylvian polymicrogyria.
Topics: Abdominal Pain; Adolescent; Adult; Cerebral Cortex; Electroencephalography; Epilepsy, Temporal Lobe; | 1998 |
A new pyrrolyl-quinoxalinedione series of non-NMDA glutamate receptor antagonists: pharmacological characterization and comparison with NBQX and valproate in the kindling model of epilepsy.
Topics: Amygdala; Animals; Anticonvulsants; Binding, Competitive; Cell Death; Electroshock; Epilepsy, Tempor | 1999 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; | 2000 |
A girl who laughed and fell down.
Topics: Anticonvulsants; Child; Diagnosis, Differential; Electroencephalography; Epilepsy, Temporal Lobe; Fe | 2000 |
Encephalopathy with epileptic spasms resolved with corticoids in a 69 year-old patient.
Topics: Aged; Anti-Inflammatory Agents; Anticonvulsants; Brain; Drug Therapy, Combination; Electroencephalog | 2000 |
Antiepileptic drug withdrawal in patients with temporal lobe epilepsy undergoing presurgical video-EEG monitoring.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy, Complex Partial | 2001 |
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Tempo | 1975 |
Stupor following administration of valproic acid to patients receiving other antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography; Epilep | 1979 |
Sodium valproate and clonazepam in the treatment of intractable epilepsy.
Topics: Adolescent; Adult; Benzodiazepinones; Child; Clonazepam; Drug Evaluation; Epilepsy; Epilepsy, Absenc | 1977 |
The anticonvulsant action of sodium valproate (Epilim) in 100 patients with various forms of epilepsy.
Topics: Adolescent; Adult; Child; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lob | 1977 |
[Clinical study of serum level of dipropylacetic acid sodium (Depakene) by gaschromatography (author's transl)].
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Gas; Drug Therapy, Combination; Epilepsi | 1977 |
[Reflections on temporal epilepsy in the child].
Topics: Adolescent; Anticonvulsants; Epilepsy, Temporal Lobe; Humans; Male; Phenobarbital; Phenytoin; Social | 1976 |
The treatment of childhood epilepsy with sodium valproate.
Topics: Adolescent; Child; Child, Preschool; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, | 1975 |
[Austrian complex-study on dipropylacetate. Pediatric experiences].
Topics: Austria; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans | 1976 |
Sodium valproate in the treatment of resistant epilepsy.
Topics: Adolescent; Adult; Alopecia; Anticonvulsants; Body Weight; Diarrhea; Drug Interactions; Epilepsies, | 1976 |
[The effect of dipropyl acetic acid (Convules) in epileptic adults with a high frequency of seizures].
Topics: Adult; Aged; Barbiturates; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-C | 1976 |
Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.
Topics: Adult; Carbamazepine; Cognition; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Humans; Male | 1991 |
The effects of clonazepam on rolandic discharge of benign epilepsy of children with centro-temporal EEG foci.
Topics: Adolescent; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Electroencephalography; Epi | 1991 |
Common epileptic syndromes in children.
Topics: Adolescent; Adrenocorticotropic Hormone; Carbamazepine; Child; Child, Preschool; Electroencephalogra | 1991 |
[A long-term follow-up of 29 cases of benign epilepsy in childhood with central-temporal electroencephalographic foci].
Topics: Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal Lobe; Female; Follow-Up Studies; | 1991 |
Epilepsy, myasthenia gravis, and effect of plasmapheresis on antiepileptic drug concentrations.
Topics: Adult; Anticonvulsants; Combined Modality Therapy; Drug Therapy, Combination; Epilepsy, Temporal Lob | 1990 |
Depression, anxiety, and temporal lobe epilepsy. Laterality of focus and symptoms.
Topics: Adult; Analysis of Variance; Anxiety; Carbamazepine; Depression; Epilepsy, Temporal Lobe; Female; Fu | 1990 |
Valproate-induced coma with ketosis and carnitine insufficiency.
Topics: Acids; Adult; Carnitine; Coma; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Humans; Ketosis | 1990 |
High-dose sodium valproate therapy for childhood refractory epilepsy.
Topics: Adolescent; Child; Child, Preschool; Dose-Response Relationship, Drug; Electroencephalography; Epile | 1990 |
[Valproic acid and stupor].
Topics: Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Male; Middle Aged; Phenytoin; Unconsciou | 1990 |
Sensorineural hearing loss: a reversible effect of valproic acid.
Topics: Aged; Audiometry; Epilepsy, Temporal Lobe; Hearing Loss, Sensorineural; Humans; Male; Phenobarbital; | 1990 |
Valproate in the treatment of temper outbursts.
Topics: Epilepsy, Temporal Lobe; Humans; Male; Middle Aged; Neurocognitive Disorders; Psychiatric Status Rat | 1990 |
Evoked metabolic responses in the limbic-striate system produced by stimulation of anterior thalamic nucleus in man.
Topics: Adult; Brain; Carbamazepine; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Female; Glucose; | 1987 |
A case of anorexia nervosa associated with epileptic seizures showing favorable responses to sodium valproate and clonazepam.
Topics: Adolescent; Anorexia Nervosa; Clonazepam; Drug Therapy, Combination; Electroencephalography; Epileps | 1989 |
Sustained attention during the interictal period of mentally normal children with epilepsy or febrile convulsions, and the influence of anticonvulsants and seizures on attention.
Topics: Anticonvulsants; Attention; Carbamazepine; Child; Drug Therapy, Combination; Epilepsies, Partial; Ep | 1989 |
Acute psychosis with carbamazepine and sodium valproate.
Topics: Acute Disease; Adult; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy, Tempora | 1989 |
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, | 1986 |
[Possible uses of Convulsofin liquid in the treatment of pediatric epilepsies].
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Epilepsies, Myoclonic; Epilepsies, Partia | 1986 |
[Treatment of epileptic patients with Jacksonian seizures].
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Drug Therapy, Combination; Epilepsies, Partial; Epilep | 1986 |
[Epilepsy with continuous discharges during slow-wave sleep. Treatment with clobazam].
Topics: Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Carbamazepine; Child; Child, Preschool; Clo | 1986 |
Clinical valproate toxicity induced by acetylsalicylic acid.
Topics: Adolescent; Aspirin; Child; Child, Preschool; Drug Interactions; Epilepsy, Temporal Lobe; Female; Hu | 1987 |
Serum valproate concentrations in epileptic children with favourable responses.
Topics: Adolescent; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy | 1987 |
'Perming' effects associated with chronic valproate therapy.
Topics: Adult; Epilepsy, Temporal Lobe; Female; Hair; Humans; Time Factors; Valproic Acid | 1988 |
Ictus emeticus induced by photic stimulation.
Topics: Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Middle Aged | 1988 |
Complex partial seizures: EEG foci and response to carbamazepine and sodium valproate.
Topics: Adolescent; Adult; Carbamazepine; Child; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hu | 1985 |
[State of confusion induced by valproic acid and reversed after administration of clonazepam].
Topics: Adult; Benzodiazepinones; Clonazepam; Cognition Disorders; Confusion; Drug Therapy, Combination; Ele | 1985 |
Where, why, and what type of therapy.
Topics: Carbamazepine; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Hum | 1985 |