valproic acid has been researched along with Epilepsy, Reflex in 34 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Epilepsy, Reflex: A subtype of epilepsy characterized by seizures that are consistently provoked by a certain specific stimulus. Auditory, visual, and somatosensory stimuli as well as the acts of writing, reading, eating, and decision making are examples of events or activities that may induce seizure activity in affected individuals. (From Neurol Clin 1994 Feb;12(1):57-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The blocking effects of valproate (2-propylpentanoic acid), a standard anti-epileptic drug, on metaphit (1-[1-(3-isothiocyanatophenyl)-cyclohexyl]-piperidine)-induced audiogenic seizures as a model of generalized, reflex audiogenic epilepsy in adult Wistar male rats were studied." | 3.74 | Anticonvulsant, but not antiepileptic, action of valproate on audiogenic seizures in metaphit-treated rats. ( Hrncić, DR; Stanojlović, OP; Susić, VT; Zivanović, DP, 2007) |
| "Our study confirms that photosensitive epilepsy has a good prognosis for seizure control that is independent of the persistence or disappearance of photosensitivity." | 2.71 | Photosensitivity and epilepsy: a follow-up study. ( Chiarelli, F; Cutarella, R; di Corcia, G; Latini, G; Salladini, C; Trotta, D; Verrotti, A, 2004) |
| "Reflex epileptic seizures can often be prevented by avoidance or modification of triggers or by prophylactic benzodiazepine administration." | 2.53 | Reflex epileptic mechanisms in ictogenesis and therapeutic consequences. ( Guaranha, M; Lin, K; Wolf, P, 2016) |
| "Eating-induced seizures are an uncommon presentation of reflex epilepsy, a condition characterized by seizures provoked by specific stimuli." | 1.36 | Unilateral opercular lesion and eating-induced seizures. ( Friedman, DE; Kung, DH; Manyam, SC; Newmark, ME; Rhodes, LB, 2010) |
| "Metaphit-treated rats displaying seizures in 8 previous tests were i." | 1.33 | Delta-sleep-inducing peptide potentiates anticonvulsive activity of valproate against metaphit-provoked audiogenic seizure in rats. ( Hrncić, D; Stanojlović, O; Susić, V; Zivanović, D, 2006) |
| "Reflex myoclonic epilepsy of infancy is an idiopathic epileptic disorder characterized by myoclonic attacks, with onset in the first 2 years of life precipitated exclusively by unexpected tactile or auditory stimuli." | 1.32 | Reflex myoclonic epilepsy in infancy: a benign age-dependent idiopathic startle epilepsy. ( Kontopoulos, E; Vargiami, E; Zafeiriou, D, 2003) |
| "This case of non-progressive reflex myoclonic epilepsy of infancy triggered only by head tapping (and not by acoustic stimuli) is an extremely rare phenomenon." | 1.32 | An unusual case of benign reflex myoclonic epilepsy of infancy. ( King, MD; Kurian, MA, 2003) |
| "A patient suffering from juvenile myoclonic epilepsy experienced myoclonic jerks, fairly regularly, while playing chess." | 1.32 | Chess-playing epilepsy: a case report with video-EEG and back averaging. ( Debrand, E; Gueguen, B; Guillou, S; Mann, MW; Soufflet, C, 2004) |
| "Reflex epilepsy is the commonest form of epilepsy in which seizures are provoked by specific external stimulus." | 1.31 | Video game epilepsy. ( Bhalla, A; Lehl, SS; Sachdev, A; Singh, R, 2001) |
| "Metoprolol was less active and atenolol was unable to affect audiogenic seizures." | 1.31 | Influence of some beta-adrenoceptor antagonists on the anticonvulsant potency of antiepileptic drugs against audiogenic seizures in DBA/2 mice. ( De Sarro, A; De Sarro, G; Di Paola, ED; Ferreri, G; Fischer, W, 2002) |
| " Repeating the EEG after the dosage has been lowered will help avoiding unnecessary recurrence of seizures." | 1.31 | [Television, children and epilepsy]. ( Dekker, E; Stroink, H; Trenité, DG, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 25 (73.53) | 29.6817 |
| 2010's | 9 (26.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, L | 1 |
| Guo, D | 1 |
| Liu, YY | 1 |
| Qiao, DD | 1 |
| Ye, JY | 1 |
| Xue, R | 1 |
| Jabeen, SA | 1 |
| Chowdary, AH | 1 |
| Mridula, KR | 1 |
| Cherian, A | 1 |
| Kumar, PR | 1 |
| Sarva, S | 1 |
| Murty, CV | 1 |
| Barrera-Bailón, B | 1 |
| Oliveira, JA | 1 |
| López, DE | 1 |
| Muñoz, LJ | 1 |
| Garcia-Cairasco, N | 1 |
| Sancho, C | 1 |
| Verrotti, A | 3 |
| Grosso, S | 1 |
| D'Egidio, C | 1 |
| Parisi, P | 2 |
| Spalice, A | 1 |
| Pavone, P | 1 |
| Capovilla, G | 2 |
| Agostinelli, S | 1 |
| Perry, G | 1 |
| Brindley, LM | 1 |
| Muthukumaraswamy, SD | 1 |
| Singh, KD | 1 |
| Hamandi, K | 1 |
| Lin, K | 1 |
| Guaranha, M | 1 |
| Wolf, P | 2 |
| Chirchiglia, D | 1 |
| Torre, AD | 1 |
| Volpentesta, G | 1 |
| Lavano, SM | 1 |
| Lavano, A | 1 |
| Borzi', G | 1 |
| Etemadifar, M | 1 |
| Raoufi, M | 1 |
| Maghzi, AH | 1 |
| Ebrahimi, A | 1 |
| Kaji-Esfahani, M | 1 |
| Mousavi, SA | 1 |
| Fiori, F | 1 |
| Coppola, G | 1 |
| Franzoni, E | 1 |
| Chiarelli, F | 2 |
| Manyam, SC | 1 |
| Kung, DH | 1 |
| Rhodes, LB | 1 |
| Newmark, ME | 1 |
| Friedman, DE | 1 |
| Savina, TA | 3 |
| Shchipakina, TG | 3 |
| Adachi, M | 1 |
| Tsuneishi, S | 1 |
| Nakamura, H | 1 |
| Shahar, E | 1 |
| Barak, S | 1 |
| Zafeiriou, D | 1 |
| Vargiami, E | 1 |
| Kontopoulos, E | 1 |
| Kurian, MA | 1 |
| King, MD | 1 |
| Chifari, R | 1 |
| Piazzini, A | 1 |
| Turner, K | 1 |
| Canger, R | 1 |
| Canevini, MP | 1 |
| Trotta, D | 1 |
| Salladini, C | 1 |
| di Corcia, G | 1 |
| Latini, G | 1 |
| Cutarella, R | 1 |
| Singhi, PD | 1 |
| Bansal, D | 1 |
| Anyanwu, EC | 1 |
| Ehiri, JE | 1 |
| Campbell, AW | 1 |
| Burneo, JG | 1 |
| Miller, S | 1 |
| Bebin, EM | 1 |
| Prasad, A | 1 |
| Mann, MW | 1 |
| Gueguen, B | 1 |
| Guillou, S | 1 |
| Debrand, E | 1 |
| Soufflet, C | 1 |
| Watanabe, K | 1 |
| Sayres, R | 1 |
| Shimojo, S | 1 |
| Imada, T | 1 |
| Nihei, K | 1 |
| Hrncić, D | 3 |
| Stanojlović, O | 3 |
| Zivanović, D | 2 |
| Susić, V | 3 |
| Aldenkamp, A | 1 |
| Vigevano, F | 1 |
| Arzimanoglou, A | 1 |
| Covanis, A | 1 |
| Rasić, A | 2 |
| Beccaria, F | 1 |
| Gambardella, A | 1 |
| Montagnini, A | 1 |
| Avantaggiato, P | 1 |
| Seri, S | 1 |
| Balashova, OA | 2 |
| Stanojlović, OP | 1 |
| Hrncić, DR | 1 |
| Zivanović, DP | 1 |
| Susić, VT | 1 |
| Loncar-Stevanović, H | 1 |
| Djuric, D | 1 |
| Salas-Puig, J | 1 |
| Parra, J | 1 |
| Fernández-Torre, JL | 1 |
| Singh, R | 1 |
| Bhalla, A | 1 |
| Lehl, SS | 1 |
| Sachdev, A | 1 |
| De Sarro, G | 1 |
| Di Paola, ED | 1 |
| Ferreri, G | 1 |
| De Sarro, A | 1 |
| Fischer, W | 1 |
| Stroink, H | 1 |
| Dekker, E | 1 |
| Trenité, DG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of New Lenses in Abolishing Photoparoxysmal Responses in Paediatric Patients With Photosensitive Epilepsy (PSE)[NCT04076410] | 76 participants (Anticipated) | Interventional | 2021-02-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for valproic acid and Epilepsy, Reflex
| Article | Year |
|---|---|
Juvenile myoclonic epilepsy and sleep.
Topics: Adolescent; Adult; Circadian Rhythm; Electroencephalography; Epilepsy, Reflex; Female; Humans; Male; | 2018 |
Reflex epileptic mechanisms in ictogenesis and therapeutic consequences.
Topics: Epilepsies, Partial; Epilepsy; Epilepsy, Reflex; Humans; Seizures; Valproic Acid | 2016 |
[Eyelid myoclonia with absences (EMA)].
Topics: Anticonvulsants; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; Epilepsie | 2002 |
Self induced photosensitive epilepsy.
Topics: Anticonvulsants; Child; Electroencephalography; Epilepsy, Reflex; Female; Humans; Photic Stimulation | 2004 |
Role of valproate across the ages. Treatment of epilepsy in children.
Topics: Anticonvulsants; Child; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epi | 2006 |
[Photogenic epilepsy].
Topics: Adolescent; Adult; Animals; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilep | 2000 |
2 trials available for valproic acid and Epilepsy, Reflex
| Article | Year |
|---|---|
Idiopathic generalized tonic-clonic epilepsy and photosensitivity: a long-term follow-up study.
Topics: Adolescent; Anticonvulsants; Chi-Square Distribution; Child; Drug Therapy, Combination; Electroencep | 2009 |
Photosensitivity and epilepsy: a follow-up study.
Topics: Adolescent; Anticonvulsants; Chi-Square Distribution; Child; Child, Preschool; Drug Therapy, Combina | 2004 |
26 other studies available for valproic acid and Epilepsy, Reflex
| Article | Year |
|---|---|
Pure graphogenic epilepsy--a rare form of reflex epilepsy.
Topics: Anticonvulsants; Electroencephalography; Epilepsy, Reflex; Humans; Magnetic Resonance Imaging; Male; | 2013 |
Pharmacological and neuroethological studies of three antiepileptic drugs in the Genetic Audiogenic Seizure Hamster (GASH:Sal).
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Chromatography, High Pressure Liqu | 2013 |
Valproate in adolescents with photosensitive epilepsy with generalized tonic-clonic seizures only.
Topics: Adolescent; Anticonvulsants; Child; Electroencephalography; Epilepsy, Reflex; Epilepsy, Tonic-Clonic | 2014 |
Evidence for increased visual gamma responses in photosensitive epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Child; Epilepsy, Generalized; Epilepsy, Reflex; Evoked Po | 2014 |
Hemiplegic migraine and late-onset photosensitive epileptic seizures.
Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsy, Reflex; Female; Glycosides; Humans; Migrai | 2016 |
Television-provoked epilepsy in children: a follow-up survey from Isfahan, Iran.
Topics: Anticonvulsants; Carbamazepine; Child; Electroencephalography; Epilepsy, Reflex; Female; Follow-Up S | 2008 |
Unilateral opercular lesion and eating-induced seizures.
Topics: Anticonvulsants; Brain Neoplasms; Cerebral Cortex; Diagnosis, Differential; Eating; Electroencephalo | 2010 |
cAMP-dependent phosphorylation of microtubule-associated protein-2 during treatment of sodium valproate and audiogenic kindling.
Topics: Analysis of Variance; Anticonvulsants; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Acti | 2011 |
Favorable outcome of epileptic blindness in children.
Topics: Acute Disease; Adolescent; Anticonvulsants; Blindness, Cortical; Carbamazepine; Child; Electroenceph | 2003 |
Reflex myoclonic epilepsy in infancy: a benign age-dependent idiopathic startle epilepsy.
Topics: Acoustic Stimulation; Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsies, Myoclon | 2003 |
An unusual case of benign reflex myoclonic epilepsy of infancy.
Topics: Anticonvulsants; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Reflex; Humans; Infant; Ma | 2003 |
Reflex writing seizures in two siblings with juvenile myoclonic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Attention; Electroencephalography; Epilepsy, Reflex; Evoked Pote | 2004 |
Efficacy of sodium valproate in the treatment of photosensitive epilepsy (PSE) and the probable reasons for the persistence of occipital spikes.
Topics: Action Potentials; Adolescent; Adult; Child; Electroencephalography; Epilepsy, Reflex; Evoked Potent | 2004 |
Video-EEG study in an adult and a child with eyelid myoclonia with absences.
Topics: Adult; Anticonvulsants; Child; Dominance, Cerebral; Drug Therapy, Combination; Electroencephalograph | 2004 |
Chess-playing epilepsy: a case report with video-EEG and back averaging.
Topics: Adult; Anticonvulsants; Attention; Electroencephalography; Electromyography; Epilepsies, Myoclonic; | 2004 |
Effect of sodium valproate on neuromagnetic responses to chromatic flicker: implication for photosensitivity.
Topics: Adolescent; Adult; Color; Epilepsy, Reflex; Female; Flicker Fusion; Humans; Magnetoencephalography; | 2004 |
Delta-sleep-inducing peptide potentiates anticonvulsive activity of valproate against metaphit-provoked audiogenic seizure in rats.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Delta Sleep-Inducing Peptide; Drug Combinations; Epi | 2006 |
Valproate and delta-sleep peptide display high efficacy against metaphit-induced audiogenic seizure in rats.
Topics: Animals; Anticonvulsants; Delta Sleep-Inducing Peptide; Dose-Response Relationship, Drug; Electroenc | 2006 |
Photosensitive benign myoclonic epilepsy in infancy.
Topics: Age of Onset; Anticonvulsants; Child; Child, Preschool; Comorbidity; Electroencephalography; Epileps | 2007 |
Effect of chronic consumption of sodium valproate and melatonin on seizure activity in Krushinskii-Molodkina rats.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Drug Combinations; Epilepsies, Myoclonic; Epilepsy, | 2006 |
Anticonvulsant, but not antiepileptic, action of valproate on audiogenic seizures in metaphit-treated rats.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Data Interpretation, Statistical; | 2007 |
Interaction of Delta sleep-inducing peptide and valproate on metaphit audiogenic seizure model in rats.
Topics: Animals; Anticonvulsants; Delta Sleep-Inducing Peptide; Disease Models, Animal; Drug Synergism; Drug | 2007 |
Ca2+/calmodulin-dependent protein kinase II--a target for sodium valproate?
Topics: Animals; Anticonvulsants; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, | 2008 |
Video game epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Reflex; Humans; Male; Valproic Acid; Video Games | 2001 |
Influence of some beta-adrenoceptor antagonists on the anticonvulsant potency of antiepileptic drugs against audiogenic seizures in DBA/2 mice.
Topics: Acoustic Stimulation; Adrenergic beta-Antagonists; Animals; Anticonvulsants; Atenolol; Body Temperat | 2002 |
[Television, children and epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Child; Electroencephalography; Epilepsy, Reflex; Female; Humans; | 2002 |