valproic acid has been researched along with Eosinophilia in 18 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Eosinophilia: Abnormal increase of EOSINOPHILS in the blood, tissues or organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a case of eosinophilic pleural effusion due to valproic acid (VPA), a rare adverse event that has been reported previously." | 8.88 | Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature. ( Da'as, N; Esayag, Y; Kamenetsky, Z; Kleinman, Y; Samuels, N, 2012) |
| "A total of 141 drug-event combinations were reported and results of disproportionality analysis indicate the positive signal of DRESS syndrome with clobazam." | 8.12 | Identification of novel signal of clobazam-associated drug reaction with eosinophilia and systemic symptoms syndrome: A disproportionality analysis. ( Kumar, A; Sharma, A, 2022) |
| " We report on the case of a 40-year-old man who experienced an eosinophilic pleural effusion with blood hypereosinophilia that occurred nine weeks after a treatment with valproic acid was introduced." | 7.77 | [Eosinophilic pleural effusion related to taking valproic acid]. ( Bally, C; Burgel, PR; Dusser, D; Kanaan, R; Kraoua, S; Lacronique, J; Martin, C, 2011) |
| "To report a case of valproic acid-induced eosinophilic pleural effusion and to review the existing literature." | 7.74 | Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature. ( Bullington, W; Judson, MA; Sahn, SA, 2007) |
| "Valproic acid is a carboxylic acid used for the treatment of both seizure and mood disorders." | 5.32 | Valproic acid-induced eosinophilic pleural effusion. ( Federman, DG; Kravetz, JD, 2003) |
| "Valproate-induced pleural effusion is rare, but patients receiving treatment with valproic acid who develop respiratory symptoms should be examined for valproate-induced pleural effusion." | 5.12 | Clinical and pathophysiological characteristics of valproate-induced pleural effusion. ( Georgopoulou, A; Ismailos, G; Papadopoulou, E; Saroglou, M; Serasli, E; Tryfon, S; Vlachopoulos, D, 2021) |
| "We present a case of eosinophilic pleural effusion due to valproic acid (VPA), a rare adverse event that has been reported previously." | 4.88 | Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature. ( Da'as, N; Esayag, Y; Kamenetsky, Z; Kleinman, Y; Samuels, N, 2012) |
| " We discuss our experience with cyclosporine treatment in a steroid-resistant DRESS syndrome caused by valproic acid in a girl, as well as her clinical, laboratory, and human leukocyte antigens (HLA) study results." | 4.12 | Valproic acid-induced DRESS in a child responding to cyclosporine with HLA analysis. ( Atasoy, AI; Ercan, N; Unay, B; Zeybek, C, 2022) |
| "A total of 141 drug-event combinations were reported and results of disproportionality analysis indicate the positive signal of DRESS syndrome with clobazam." | 4.12 | Identification of novel signal of clobazam-associated drug reaction with eosinophilia and systemic symptoms syndrome: A disproportionality analysis. ( Kumar, A; Sharma, A, 2022) |
| " We report on the case of a 40-year-old man who experienced an eosinophilic pleural effusion with blood hypereosinophilia that occurred nine weeks after a treatment with valproic acid was introduced." | 3.77 | [Eosinophilic pleural effusion related to taking valproic acid]. ( Bally, C; Burgel, PR; Dusser, D; Kanaan, R; Kraoua, S; Lacronique, J; Martin, C, 2011) |
| "To report a case of valproic acid-induced eosinophilic pleural effusion and to review the existing literature." | 3.74 | Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature. ( Bullington, W; Judson, MA; Sahn, SA, 2007) |
| " Serum interleukin-5 levels were measured with enzyme-linked immunosorbent assay technique in 68 children with epilepsy receiving sodium valproate monotherapy and compared with the levels of 60 healthy controls and 14 children with epilepsy receiving carbamazepine." | 3.73 | Valproate-induced eosinophilia in children with epilepsy: role of interleukin-5. ( Bourantas, KL; Kateri, MD; Makis, AC; Papadopoulou, ZL; Tzoufi, M, 2005) |
| "DRESS syndrome is a life-threatening adverse reaction characterized by skin rashes, fever, leukocytosis with eosinophilia or atypical lymphocytosis, lymph node enlargement, and liver or renal dysfunctions." | 1.38 | DRESS syndrome with fatal results induced by sodium valproate in a patient with brucellosis and a positive cytoplasmic antineutrophilic cytoplasmic antibody test result. ( Albayrak, A; Albayrak, F; Cerrah, S; Dursun, H; Uyanik, A; Yildirim, R, 2012) |
| "Valproic acid is a carboxylic acid used for the treatment of both seizure and mood disorders." | 1.32 | Valproic acid-induced eosinophilic pleural effusion. ( Federman, DG; Kravetz, JD, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ercan, N | 1 |
| Zeybek, C | 1 |
| Atasoy, AI | 1 |
| Unay, B | 1 |
| Sharma, A | 1 |
| Kumar, A | 1 |
| Tryfon, S | 1 |
| Papadopoulou, E | 1 |
| Saroglou, M | 1 |
| Vlachopoulos, D | 1 |
| Georgopoulou, A | 1 |
| Serasli, E | 1 |
| Ismailos, G | 1 |
| Brizendine, CE | 1 |
| Naik, PJ | 1 |
| Taktak, A | 1 |
| Acar, B | 1 |
| Gür, G | 1 |
| Tiryaki, T | 1 |
| Albayrak, A | 2 |
| Çakar, N | 1 |
| Maia, JM | 1 |
| Guedes, F | 1 |
| Aragão, I | 1 |
| Cardoso, T | 1 |
| Fernández-Pérez, R | 1 |
| Alvarez-Dobaño, JM | 1 |
| Suárez-Antelo, J | 1 |
| Codesido-Barcala, R | 1 |
| Carballal-Calvo, F | 1 |
| Arrojo-Romero, M | 1 |
| de Leon, J | 1 |
| Mardivirin, L | 1 |
| Descamps, V | 1 |
| Lacroix, A | 1 |
| Delebassée, S | 1 |
| Ranger-Rogez, S | 1 |
| Albayrak, F | 1 |
| Cerrah, S | 1 |
| Dursun, H | 1 |
| Yildirim, R | 1 |
| Uyanik, A | 1 |
| Abdelhamid, MS | 1 |
| Percival, M | 1 |
| Sivakumaran, P | 1 |
| Bally, C | 1 |
| Martin, C | 1 |
| Kraoua, S | 1 |
| Kanaan, R | 1 |
| Lacronique, J | 1 |
| Dusser, D | 1 |
| Burgel, PR | 1 |
| Kamenetsky, Z | 1 |
| Da'as, N | 1 |
| Esayag, Y | 1 |
| Kleinman, Y | 1 |
| Samuels, N | 1 |
| van Zoelen, MA | 1 |
| de Graaf, M | 1 |
| van Dijk, MR | 1 |
| Bogte, A | 1 |
| van Erpecum, KJ | 1 |
| Rockmann, H | 1 |
| Maarschalk-Ellerbroek, LJ | 1 |
| Kravetz, JD | 1 |
| Federman, DG | 1 |
| Makis, AC | 1 |
| Tzoufi, M | 1 |
| Kateri, MD | 1 |
| Bourantas, KL | 1 |
| Papadopoulou, ZL | 1 |
| Yun, SJ | 1 |
| Lee, JB | 1 |
| Kim, EJ | 1 |
| Quan, G | 1 |
| Kim, SJ | 1 |
| Won, YH | 1 |
| Lee, SC | 1 |
| Bullington, W | 1 |
| Sahn, SA | 1 |
| Judson, MA | 1 |
| Jimenez-Rodriguezvila, M | 1 |
| Caro-Patón, A | 1 |
| Conde, M | 1 |
| Dueñas-Laita, A | 1 |
| Martin-Lorente, JL | 1 |
| Fernandez Perez de Villalain, MJ | 1 |
| Gonzalez Martinez de Zarate, JL | 1 |
| Marañon, A | 1 |
2 reviews available for valproic acid and Eosinophilia
| Article | Year |
|---|---|
Clinical and pathophysiological characteristics of valproate-induced pleural effusion.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Eosinophilia; Female; Humans; Lupus Erythematosus, Systemi | 2021 |
Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature.
Topics: Adult; Eosinophilia; Exudates and Transudates; Humans; Male; Pleural Effusion; Seizures; Valproic Ac | 2012 |
16 other studies available for valproic acid and Eosinophilia
| Article | Year |
|---|---|
Valproic acid-induced DRESS in a child responding to cyclosporine with HLA analysis.
Topics: Child; Cyclosporine; Drug Hypersensitivity Syndrome; Eosinophilia; Female; Haptens; HLA Antigens; Hu | 2022 |
Identification of novel signal of clobazam-associated drug reaction with eosinophilia and systemic symptoms syndrome: A disproportionality analysis.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Clobazam; Drug Hypersensitivity Syndrome; Eosinophilia; Fema | 2022 |
Drug rash with eosinophilia and systemic symptoms syndrome associated with use of phenytoin, divalproex sodium, and phenobarbital.
Topics: Adult; Drug Eruptions; Drug Substitution; Eosinophilia; Female; Humans; Phenobarbital; Phenytoin; Va | 2013 |
An unusual cause of gross hematuria: questions and answers.
Topics: Autistic Disorder; Child; Cystitis; Eosinophilia; GABA Agents; Hematuria; Humans; Male; Valproic Aci | 2015 |
Eosinophilic pneumonia presenting as life-threatening ARDS.
Topics: Adult; Alprazolam; Antidepressive Agents, Second-Generation; Caustics; Cough; Drug Therapy, Combinat | 2015 |
Eosinophilic pleural effusion associated with the addition of sodium valproate.
Topics: Antimanic Agents; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Eosinophilia; Female; | 2009 |
Early effects of drugs responsible for DRESS on HHV-6 replication in vitro.
Topics: Carbamazepine; Cell Line, Transformed; Drug Eruptions; Eosinophilia; Herpesvirus 6, Human; Humans; V | 2009 |
DRESS syndrome with fatal results induced by sodium valproate in a patient with brucellosis and a positive cytoplasmic antineutrophilic cytoplasmic antibody test result.
Topics: Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Anticonvulsants; Brucellosis; Drug Er | 2012 |
Sodium valproate - a rare cause of eosinophilic pleural effusion.
Topics: Eosinophilia; Humans; Male; Middle Aged; Pleural Effusion; Valproic Acid | 2011 |
[Eosinophilic pleural effusion related to taking valproic acid].
Topics: Adult; Antimanic Agents; Blood Cell Count; Eosinophilia; Eosinophils; Humans; Male; Pleural Effusion | 2011 |
Valproic acid-induced DRESS syndrome with acute liver failure.
Topics: Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Eosinophilia; | 2012 |
Valproic acid-induced eosinophilic pleural effusion.
Topics: Adult; Anti-Bacterial Agents; Antimanic Agents; Ceftazidime; Chest Pain; Cough; Drainage; Drug Thera | 2003 |
Valproate-induced eosinophilia in children with epilepsy: role of interleukin-5.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child, Preschool; Eosinophi | 2005 |
Drug rash with eosinophilia and systemic symptoms induced by valproate and carbamazepine: formation of circulating auto-antibody against 190-kDa antigen.
Topics: Adult; Anticonvulsants; Autoantibodies; Carbamazepine; Cross Reactions; Diagnosis, Differential; Dru | 2006 |
Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature.
Topics: Adult; Eosinophilia; Humans; Male; Pleural Effusion; Valproic Acid | 2007 |
Side-effects of sodium valproate, mainly related to its hepatic and pancreatic toxicity.
Topics: Adolescent; Adult; Aged; Amylases; Body Weight; Chemical and Drug Induced Liver Injury; Child; Child | 1986 |