valproic acid has been researched along with Enuresis in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Enuresis: Involuntary discharge of URINE after expected age of completed development of urinary control. This can happen during the daytime (DIURNAL ENURESIS) while one is awake or during sleep (NOCTURNAL ENURESIS). Enuresis can be in children or in adults (as persistent primary enuresis and secondary adult-onset enuresis).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Secondary enuresis is a common adverse event associated with valproate use in children, which is not usually spontaneously reported and is reversible in most cases." | 1.42 | Valproate-induced enuresis: a prospective study. ( Arabi, M; Beydoun, A; Hmaimess, G; Makke, Y; Nasreddine, W; Sabbagh, S; Yamak, WR, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamak, WR | 1 |
| Hmaimess, G | 1 |
| Makke, Y | 1 |
| Sabbagh, S | 1 |
| Arabi, M | 1 |
| Beydoun, A | 1 |
| Nasreddine, W | 1 |
| Panayiotopoulos, CP | 1 |
| Choonara, IA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PSG in Valproate-induced Nocturnal Enuresis in Children[NCT04191863] | 260 participants (Actual) | Observational | 2018-09-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for valproic acid and Enuresis
| Article | Year |
|---|---|
Valproate-induced enuresis: a prospective study.
Topics: Age Factors; Anticonvulsants; Child; Child, Preschool; Enuresis; Epilepsy; Female; Humans; Male; Pro | 2015 |
Nocturnal enuresis associated with sodium valproate.
Topics: Child; Enuresis; Female; Humans; Valproic Acid | 1985 |
Sodium valproate and enuresis.
Topics: Enuresis; Humans; Valproic Acid | 1985 |