valproic acid has been researched along with Endometrial Neoplasms in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Endometrial Neoplasms: Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.
| Excerpt | Relevance | Reference |
|---|
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yi, TZ | 1 |
| Li, J | 1 |
| Han, X | 1 |
| Guo, J | 1 |
| Qu, Q | 1 |
| Guo, L | 1 |
| Sun, HD | 1 |
| Tan, WH | 1 |
| Graziani, G | 1 |
| Tentori, L | 1 |
| Portarena, I | 1 |
| Vergati, M | 1 |
| Navarra, P | 1 |
| Takai, N | 1 |
| Desmond, JC | 1 |
| Kumagai, T | 1 |
| Gui, D | 1 |
| Said, JW | 1 |
| Whittaker, S | 1 |
| Miyakawa, I | 1 |
| Koeffler, HP | 1 |
| Hrzenjak, A | 1 |
| Moinfar, F | 1 |
| Kremser, ML | 1 |
| Strohmeier, B | 1 |
| Staber, PB | 1 |
| Zatloukal, K | 1 |
| Denk, H | 1 |
4 other studies available for valproic acid and Endometrial Neoplasms
| Article | Year |
|---|---|
DNMT inhibitors and HDAC inhibitors regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azacitidine; Cadherins; Carcinoma; Cell Cycle Checkpoints | 2012 |
Valproic acid increases the stimulatory effect of estrogens on proliferation of human endometrial adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Division; Drug Synergism; Endometrial Neoplasms; Enzyme Inhibitors; Estradiol; | 2003 |
Histone deacetylase inhibitors have a profound antigrowth activity in endometrial cancer cells.
Topics: Agar; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cadherins; Cell Cycle Proteins; | 2004 |
Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells.
Topics: Cell Differentiation; Cell Growth Processes; Cyclin-Dependent Kinase Inhibitor p21; Endometrial Neop | 2006 |