valproic acid has been researched along with Endocrine System Diseases in 9 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Endocrine System Diseases: Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carbamazepine and depakine treatment during at least 6 months does not predispose to ovary polycystosis syndrome." | 5.31 | [The pharmacological and hormonal effects of carbamazepine and valproic acid in the treatment of reproductive age women with epilepsy]. ( Karlov, VA; Kushlinskiĭ, NE; Vlasov, PN, 2001) |
| "Valproic acid (VPA) is a broad spectrum antiepileptic drug (AED) that is generally regarded as a first-choice agent for most forms of idiopathic and symptomatic generalised epilepsies." | 2.53 | Valproic Acid Metabolism and its Consequences on Sexual Functions. ( Belcastro, V; Castagnino, M; Cofini, M; Leo, A; Mencaroni, E; Russo, E; Verrotti, A, 2016) |
| "Both seizures and antiepileptic drugs may induce disturbances in hormonal system." | 2.44 | [Endocrine effects of antiepileptic drugs]. ( Budziszewska, B; Lasoń, W; Leśkiewicz, M, 2008) |
| " Endocrine and metabolic adverse effects are among the most concerning adverse effects of commonly used psychotropic medications." | 2.43 | Endocrine and metabolic adverse effects of psychotropic medications in children and adolescents. ( Carlson, HE; Correll, CU, 2006) |
| "The effect of comorbid substance use on the likelihood of response differed significantly according to baseline BMI." | 1.36 | Medical comorbidity in bipolar disorder: relationship between illnesses of the endocrine/metabolic system and treatment outcome. ( Calabrese, JR; Chan, PK; Findling, RL; Ganocy, SJ; Gao, K; Kemp, DE, 2010) |
| "A possible role of the seizure disorder or, alternatively, of the use of antiepileptic drugs (AEDs) has been suggested as the pathogenic mechanism." | 1.31 | Characterization of reproductive endocrine disorders in women with epilepsy. ( Bilo, L; Di Carlo, C; Meo, R; Nappi, C; Striano, S; Valentino, R, 2001) |
| "Carbamazepine and depakine treatment during at least 6 months does not predispose to ovary polycystosis syndrome." | 1.31 | [The pharmacological and hormonal effects of carbamazepine and valproic acid in the treatment of reproductive age women with epilepsy]. ( Karlov, VA; Kushlinskiĭ, NE; Vlasov, PN, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Verrotti, A | 1 |
| Mencaroni, E | 1 |
| Cofini, M | 1 |
| Castagnino, M | 1 |
| Leo, A | 1 |
| Russo, E | 1 |
| Belcastro, V | 1 |
| Leśkiewicz, M | 1 |
| Budziszewska, B | 1 |
| Lasoń, W | 1 |
| Kenna, HA | 1 |
| Jiang, B | 1 |
| Rasgon, NL | 2 |
| Kemp, DE | 1 |
| Gao, K | 1 |
| Chan, PK | 1 |
| Ganocy, SJ | 1 |
| Findling, RL | 1 |
| Calabrese, JR | 1 |
| Altshuler, LL | 1 |
| Fairbanks, L | 1 |
| Elman, S | 1 |
| Bitran, J | 1 |
| Labarca, R | 1 |
| Saad, M | 1 |
| Kupka, R | 1 |
| Nolen, WA | 1 |
| Frye, MA | 1 |
| Suppes, T | 1 |
| McElroy, SL | 1 |
| Keck, PE | 1 |
| Leverich, G | 1 |
| Grunze, H | 1 |
| Walden, J | 1 |
| Post, R | 1 |
| Mintz, J | 1 |
| Correll, CU | 1 |
| Carlson, HE | 1 |
| Isojärvi, JI | 1 |
| Laatikainen, TJ | 1 |
| Knip, M | 1 |
| Pakarinen, AJ | 1 |
| Juntunen, KT | 1 |
| Myllylä, VV | 1 |
| Bilo, L | 1 |
| Meo, R | 1 |
| Valentino, R | 1 |
| Di Carlo, C | 1 |
| Striano, S | 1 |
| Nappi, C | 1 |
| Vlasov, PN | 1 |
| Karlov, VA | 1 |
| Kushlinskiĭ, NE | 1 |
4 reviews available for valproic acid and Endocrine System Diseases
| Article | Year |
|---|---|
Valproic Acid Metabolism and its Consequences on Sexual Functions.
Topics: Animals; Anticonvulsants; Biotransformation; Endocrine System; Endocrine System Diseases; Female; Hu | 2016 |
[Endocrine effects of antiepileptic drugs].
Topics: Anticonvulsants; Carbamazepine; Endocrine System Diseases; Estradiol; Female; Hormones; Humans; Leve | 2008 |
Reproductive and metabolic abnormalities associated with bipolar disorder and its treatment.
Topics: Bipolar Disorder; Dyslipidemias; Endocrine System Diseases; Female; Humans; Hypogonadism; Hypothalam | 2009 |
Endocrine and metabolic adverse effects of psychotropic medications in children and adolescents.
Topics: Adolescent; Antipsychotic Agents; Child; Dibenzothiazepines; Drug Administration Schedule; Endocrine | 2006 |
5 other studies available for valproic acid and Endocrine System Diseases
| Article | Year |
|---|---|
Medical comorbidity in bipolar disorder: relationship between illnesses of the endocrine/metabolic system and treatment outcome.
Topics: Adult; Bipolar Disorder; Body Mass Index; Comorbidity; Endocrine System Diseases; Female; Humans; Li | 2010 |
Reproductive function and risk for PCOS in women treated for bipolar disorder.
Topics: Adolescent; Adult; Antimanic Agents; Bipolar Disorder; Endocrine System Diseases; Female; Humans; Me | 2005 |
Obesity and endocrine disorders in women taking valproate for epilepsy.
Topics: Adult; Body Weight; Carbamazepine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Endocrine | 1996 |
Characterization of reproductive endocrine disorders in women with epilepsy.
Topics: Adolescent; Adult; Amenorrhea; Anticonvulsants; Endocrine System Diseases; Epilepsy; Female; Humans; | 2001 |
[The pharmacological and hormonal effects of carbamazepine and valproic acid in the treatment of reproductive age women with epilepsy].
Topics: Adult; Anticonvulsants; Carbamazepine; Endocrine System Diseases; Epilepsy; Estradiol; Female; Folli | 2001 |