Page last updated: 2024-10-26

valproic acid and Emesis

valproic acid has been researched along with Emesis in 19 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"The objective of the study was to compare the antiaggressive efficacy of risperidone monotherapy versus risperidone plus valproate in patients with schizophrenia."9.12Risperidone alone versus risperidone plus valproate in the treatment of patients with schizophrenia and hostility. ( Citrome, L; Czobor, P; Nolan, KA; Shope, CB; Volavka, J, 2007)
"Four patients had pancreatitis associated with valproic acid therapy."7.67Pancreatitis associated with valproic acid therapy. ( Cruse, RP; Erenberg, G; Rothner, AD; Wyllie, E; Wyllie, R, 1984)
"The objective of the study was to compare the antiaggressive efficacy of risperidone monotherapy versus risperidone plus valproate in patients with schizophrenia."5.12Risperidone alone versus risperidone plus valproate in the treatment of patients with schizophrenia and hostility. ( Citrome, L; Czobor, P; Nolan, KA; Shope, CB; Volavka, J, 2007)
"Four patients had pancreatitis associated with valproic acid therapy."3.67Pancreatitis associated with valproic acid therapy. ( Cruse, RP; Erenberg, G; Rothner, AD; Wyllie, E; Wyllie, R, 1984)
" Four patients experienced relapse with a decreased dosage of valproate."2.74Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate. ( Amakata, K; Fujii, Y; Hikita, T; Kaga, F; Kaneko, S; Kodama, H; Nakamoto, N; Ogita, K; Yanagawa, Y, 2009)
"Patients with migraines have typically been given one group of medications for abortive treatment and another for preventative."1.31Use of intravenous valproate sodium in status migraine. ( Norton, J, 2000)
"Valproic acid was proved to be effective in reducing the number of attacks over 4 months."1.30Periodic discharge of adrenocorticotropin and vasopressin associated with focal glomerulosclerosis. ( Fujieda, M; Kurashige, T; Machida, Y; Maeda, A; Maeda, H; Naruse, K; Okada, T; Ushida, M; Wakiguchi, H; Yokoyama, W, 1998)
"Mild signs of HPNS (e."1.28Sodium valproate interactions with the HPNS: EEG and behavioral observations. ( Clarke, D; Doré, CJ; Halsey, MJ; Luff, NP; Maclean, CJ; Pearce, PC, 1989)
" A twice daily dosage regime was satisfactory."1.26Sodium valproate (Epilim) in epilepsy: a trial. ( Briant, RH; Foote, SE; Wallis, WE, 1978)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19907 (36.84)18.7374
1990's1 (5.26)18.2507
2000's10 (52.63)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jackson, R1
Toubia, N1
Dhaliwal, G1
Bottomley, SS1
Bronze, MS1
Hikita, T3
Kodama, H3
Nakamoto, N3
Kaga, F2
Amakata, K2
Ogita, K3
Kaneko, S3
Fujii, Y3
Yanagawa, Y3
Fujita, Y1
Suzuki, Y1
Igarashi, K1
Gelfand, AA1
Goadsby, PJ1
Yukselen, V1
Yasa, MH1
Karaoglu, AO1
Bolukbasi, O1
Parisi, P1
Ferri, R1
Pagani, J1
Cecili, M1
Montemitro, E1
Villa, MP1
Citrome, L1
Shope, CB1
Nolan, KA1
Czobor, P1
Volavka, J1
Shiga, K1
Nakazato, Y1
Tamura, N1
Shimazu, K1
Wyllie, E1
Wyllie, R1
Cruse, RP1
Erenberg, G1
Rothner, AD1
Egger, J1
Brett, EM1
Seghieri, G1
De Giorgio, LA1
Innocenti, F1
Pettiná, G1
Zolfanelli, F1
Apicella, P1
Yokoyama, W1
Fujieda, M1
Okada, T1
Maeda, H1
Ushida, M1
Machida, Y1
Naruse, K1
Maeda, A1
Wakiguchi, H1
Kurashige, T1
Levine, J1
Chengappa, KN1
Parepally, H1
Norton, J1
Briant, RH1
Foote, SE1
Wallis, WE1
Hassan, MN1
Laljee, HC1
Parsonage, MJ1
Pearce, PC1
Clarke, D1
Doré, CJ1
Halsey, MJ1
Luff, NP1
Maclean, CJ1
Jacome, DE1
Suarez, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Risperidone Alone Vs. Risperidone Plus Valproate in the Treatment of Patients With Schizophrenia and Hostility[NCT00308360]Phase 446 participants Interventional1999-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for valproic acid and Emesis

ArticleYear
Treatment of pediatric migraine in the emergency room.
    Pediatric neurology, 2012, Volume: 47, Issue:4

    Topics: Adolescent; Age Distribution; Age of Onset; Analgesics; Antiemetics; Child; Child, Preschool; Dihydr

2012

Trials

2 trials available for valproic acid and Emesis

ArticleYear
Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate.
    Brain & development, 2009, Volume: 31, Issue:6

    Topics: Anticonvulsants; Child; Child, Preschool; Dehydration; Dose-Response Relationship, Drug; Drug Admini

2009
Risperidone alone versus risperidone plus valproate in the treatment of patients with schizophrenia and hostility.
    International clinical psychopharmacology, 2007, Volume: 22, Issue:6

    Topics: Adult; Aggression; Anticonvulsants; Antipsychotic Agents; Diarrhea; Drug Therapy, Combination; Femal

2007

Other Studies

16 other studies available for valproic acid and Emesis

ArticleYear
A confusing case of confusion. Acute porphyrias.
    The Journal of the Oklahoma State Medical Association, 2008, Volume: 101, Issue:4

    Topics: Acidosis, Lactic; Acute Disease; Anticonvulsants; Brain; Confusion; Diagnosis, Differential; Diet, R

2008
[The effect of prophylactic therapy with valproate sodium and phenobarbital in two patients with cyclic vomiting syndrome].
    No to hattatsu = Brain and development, 2008, Volume: 40, Issue:5

    Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Male; Phenobarbital; Valproic Ac

2008
Partial seizure: an unusual cause of recurrent vomiting.
    International journal of clinical practice, 2003, Volume: 57, Issue:8

    Topics: Anticonvulsants; Electroencephalography; Epilepsies, Partial; Humans; Male; Middle Aged; Treatment O

2003
Ictal video-polysomnography and EEG spectral analysis in a child with severe Panayiotopoulos syndrome.
    Epileptic disorders : international epilepsy journal with videotape, 2005, Volume: 7, Issue:4

    Topics: Anticonvulsants; Child; Electroencephalography; Epilepsies, Partial; Eye Movements; Hallucinations;

2005
[Valproate sodium is effective as prophylactic therapy for cyclic vomiting syndrome in a case].
    No to hattatsu = Brain and development, 2008, Volume: 40, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Humans; Infant; Male; Syndrome; Valproic Acid; Vomiting

2008
An adult case of cyclic vomiting syndrome successfully responding to valproic acid.
    Journal of neurology, 2008, Volume: 255, Issue:6

    Topics: Anti-Anxiety Agents; Anticonvulsants; Antiemetics; Consciousness Disorders; Diazepam; Female; Humans

2008
Pancreatitis associated with valproic acid therapy.
    American journal of diseases of children (1960), 1984, Volume: 138, Issue:10

    Topics: Abdomen; Adolescent; Adult; Amylases; Blood Coagulation Disorders; Child; Child, Preschool; Female;

1984
Effects of sodium valproate in 100 children with special reference to weight.
    British medical journal (Clinical research ed.), 1981, Aug-29, Volume: 283, Issue:6291

    Topics: Adolescent; Appetite; Body Weight; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male;

1981
[Description of a case of a syndrome similar to Reye's syndrome in a male adult undergoing treatment with valproic acid and phenobarbital].
    Giornale di clinica medica, 1982, Volume: 63, Issue:9

    Topics: Adult; Brain Diseases; Coma; Epilepsy, Tonic-Clonic; Fever; Humans; Male; Muscle Rigidity; Phenobarb

1982
Periodic discharge of adrenocorticotropin and vasopressin associated with focal glomerulosclerosis.
    Acta paediatrica Japonica : Overseas edition, 1998, Volume: 40, Issue:6

    Topics: Adrenocorticotropic Hormone; Child; Glomerulosclerosis, Focal Segmental; Humans; Kidney Failure, Chr

1998
Side effect profile of enteric-coated divalproex sodium versus valproic acid.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:9

    Topics: Humans; Male; Middle Aged; Nausea; Platelet Count; Tablets, Enteric-Coated; Thrombocytopenia; Valpro

2000
Use of intravenous valproate sodium in status migraine.
    Headache, 2000, Volume: 40, Issue:9

    Topics: Acute Disease; Adult; Female; Humans; Infusions, Intravenous; Migraine Disorders; Nausea; Pain, Intr

2000
Sodium valproate (Epilim) in epilepsy: a trial.
    The New Zealand medical journal, 1978, Dec-27, Volume: 88, Issue:626

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Cloni

1978
Sodium valproate in the treatment of resistant epilepsy.
    Acta neurologica Scandinavica, 1976, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Alopecia; Anticonvulsants; Body Weight; Diarrhea; Drug Interactions; Epilepsies,

1976
Sodium valproate interactions with the HPNS: EEG and behavioral observations.
    Undersea biomedical research, 1989, Volume: 16, Issue:2

    Topics: Animals; Central Nervous System Diseases; Electroencephalography; Female; High Pressure Neurological

1989
Ictus emeticus induced by photic stimulation.
    Clinical EEG (electroencephalography), 1988, Volume: 19, Issue:4

    Topics: Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Middle Aged

1988