valproic acid has been researched along with Edema in 17 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Periorbital edema is a rare side effect of valproate." | 1.62 | Valproate-induced Periorbital Edema. ( Elhamamsy, S; Hatahet, S; Khalaf, K, 2021) |
| "Bilateral pitting edema is rare adverse drug reaction observed in the psychiatry department." | 1.48 | Sodium Valproate-Induced Bilateral Pitting Pedal Edema - A Case Report. ( Anovadiya, A; Chaudhary, D; Panchal, R, 2018) |
| "Valproic acid (VA) is a major antiepileptic drug, used for several therapeutic indications." | 1.39 | Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties. ( Correia, AO; da Graça Naffah-Mazzacorati, M; de Castro Brito, GA; de Oliveira Gonçalves, D; Félix, FH; Leal, LK; Neves, KR; Santos Cerqueira, G; Siqueira, RM; Viana, GS; Ximenes, JC, 2013) |
| "Valproate-related peripheral oedema is usually regarded as a problem occurring after long-term administration of valproate." | 1.35 | Valproate-related peripheral oedema: a manageable but probably neglected condition. ( Chen, CS; Lin, ST; Tsei, JH; Wang, SY; Yen, CF, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (35.29) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Hatahet, S | 1 |
| Khalaf, K | 1 |
| Elhamamsy, S | 1 |
| Takım, U | 1 |
| Akgül Ceyhun, H | 1 |
| Panchal, R | 1 |
| Chaudhary, D | 1 |
| Anovadiya, A | 1 |
| Ximenes, JC | 1 |
| de Oliveira Gonçalves, D | 1 |
| Siqueira, RM | 1 |
| Neves, KR | 1 |
| Santos Cerqueira, G | 1 |
| Correia, AO | 1 |
| Félix, FH | 1 |
| Leal, LK | 1 |
| de Castro Brito, GA | 1 |
| da Graça Naffah-Mazzacorati, M | 1 |
| Viana, GS | 1 |
| Gabriel, L | 1 |
| Darcissac, C | 1 |
| Goutelle, S | 1 |
| Sève, P | 1 |
| Vial, T | 1 |
| de La Gastine, B | 1 |
| Lin, ST | 1 |
| Chen, CS | 1 |
| Yen, CF | 1 |
| Tsei, JH | 1 |
| Wang, SY | 1 |
| Chen, CY | 1 |
| Yeh, YW | 1 |
| Kuo, SC | 1 |
| Shiah, IS | 1 |
| Liu, PY | 1 |
| Chen, CL | 1 |
| Ooi, WW | 1 |
| Wijemanne, S | 1 |
| Thomas, CB | 1 |
| Quezado, M | 1 |
| Brown, CR | 1 |
| Nash, TE | 1 |
| McSkimming, AJ | 1 |
| Dham, P | 1 |
| Alexander, J | 1 |
| Dinesh, A | 1 |
| Witters, I | 1 |
| Van Assche, F | 1 |
| Fryns, JP | 1 |
| Raza, M | 1 |
| Dhariwal, MA | 1 |
| Ageel, AM | 1 |
| Qureshi, S | 1 |
| Baldassano, CF | 1 |
| Ghaemi, SN | 1 |
| Sanders, RD | 1 |
| Lehrer, DS | 1 |
| Basel-Vanagaite, L | 1 |
| Zeharia, A | 1 |
| Amir, J | 1 |
| Mimouni, M | 1 |
| Sanford, MG | 1 |
| Ryan, C | 1 |
| Cummings, AD | 1 |
| Hunt, A | 1 |
| Hackes, B | 1 |
| Khoo, SH | 1 |
| Leyland, MJ | 1 |
| Buchanan, N | 1 |
| Hayden, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical, Laboratory and Imaging Features, Treatment Trends and Long Term Outcomes in Patients With Parenchymal and Extraparenchymal Neurocysticercosis-A Registry Based Study[NCT04706819] | 1,000 participants (Anticipated) | Observational [Patient Registry] | 2021-01-15 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for valproic acid and Edema
| Article | Year |
|---|---|
[Lower limb edema during valpromide treatment: case report and literature review].
Topics: Aged, 80 and over; Anticonvulsants; Edema; Female; Furosemide; Humans; Lower Extremity; Valproic Aci | 2015 |
16 other studies available for valproic acid and Edema
| Article | Year |
|---|---|
Valproate-induced Periorbital Edema.
Topics: Aged; Aggression; Alzheimer Disease; Edema; Humans; Male; Valproic Acid | 2021 |
VALPROATE-QUETIAPINE INDUCED PERIPHERAL EDEMA.
Topics: Antipsychotic Agents; Bipolar Disorder; Dibenzothiazepines; Edema; Humans; Quetiapine Fumarate; Valp | 2023 |
Sodium Valproate-Induced Bilateral Pitting Pedal Edema - A Case Report.
Topics: Adult; Antipsychotic Agents; Edema; Female; Foot; Humans; Male; Valproic Acid | 2018 |
Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Butyric Acid; Carrageenan; Drug Syne | 2013 |
Valproate-related peripheral oedema: a manageable but probably neglected condition.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Edema; Female; Humans; Middle Aged; | 2009 |
Pedal edema associated with addition of low-dose quetiapine to valproate treatment in bipolar disorder.
Topics: Aged; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Dibenzothiazepines; Edema; Female; F | 2009 |
Short report: A calcified Taenia solium granuloma associated with recurrent perilesional edema causing refractory seizures: histopathological features.
Topics: Albendazole; Animals; Anthelmintics; Anticonvulsants; Calcinosis; Edema; Granuloma; Humans; Levetira | 2011 |
Peripheral oedema in quetiapine therapy.
Topics: Antimanic Agents; Antipsychotic Agents; Depressive Disorder, Treatment-Resistant; Dibenzothiazepines | 2012 |
Nuchal edema as the first sign of fetal valproate syndrome.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Edema; Female; Gestational Age; Humans; Neck; P | 2002 |
Evaluation of the antiinflammatory activity of sodium valproate in rats and mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Body Temperature Regulation; Car | 1996 |
Generalized edema with risperidone: divalproex sodium treatment.
Topics: Adult; Bipolar Disorder; Comorbidity; Edema; Epilepsy, Temporal Lobe; Humans; Male; Risperidone; Val | 1996 |
Edema associated with addition of risperidone to valproate treatment.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Dru | 1998 |
Edema associated with valproate therapy.
Topics: Adolescent; Anticonvulsants; Edema; Epilepsy, Tonic-Clonic; Female; Humans; Valproic Acid | 1999 |
Protocols for identifying drug-nutrient interactions in patients: the role of the dietitian.
Topics: Adolescent; Adult; Anticonvulsants; Biotin; Calcium; Carnitine; Dietetics; Edema; Folic Acid; Food-D | 2002 |
Cerebral edema following acute sodium valproate overdose.
Topics: Adult; Brain Diseases; Drug Overdose; Edema; Humans; Hypocalcemia; Kidney; Liver; Male; Valproic Aci | 1992 |
Sodium valproate and oedema.
Topics: Adult; Edema; Female; Humans; Valproic Acid | 1992 |