valproic acid has been researched along with Dysthymic Disorder in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Dysthymic Disorder: Chronically depressed mood that occurs for most of the day more days than not for at least 2 years. The required minimum duration in children to make this diagnosis is 1 year. During periods of depressed mood, at least 2 of the following additional symptoms are present: poor appetite or overeating, insomnia or hypersomnia, low energy or fatigue, low self-esteem, poor concentration or difficulty making decisions, and feelings of hopelessness. (DSM-IV)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duggal, HS | 1 |
| Pathak, PC | 1 |
| Coleman, CC | 1 |
| Martínez-Arán, A | 1 |
| Vieta, E | 1 |
| Colom, F | 1 |
| Torrent, C | 1 |
| Sánchez-Moreno, J | 1 |
| Reinares, M | 1 |
| Benabarre, A | 1 |
| Goikolea, JM | 1 |
| Brugué, E | 1 |
| Daban, C | 1 |
| Salamero, M | 1 |
| Saxena, K | 1 |
| Howe, M | 1 |
| Simeonova, D | 1 |
| Steiner, H | 1 |
| Chang, K | 1 |
| Schenkel, LS | 1 |
| Pavuluri, MN | 1 |
| Herbener, ES | 1 |
| Harral, EM | 1 |
| Sweeney, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Changes in Serum miRNA and BDNF Levels in Bipolar II Depression Treated by Theta-burst Stimulation: A Randomized Sham-controlled Exploratory Study[NCT04998097] | 60 participants (Anticipated) | Interventional | 2022-05-23 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for valproic acid and Dysthymic Disorder
| Article | Year |
|---|---|
Divalproex sodium reduces overall aggression in youth at high risk for bipolar disorder.
Topics: Adolescent; Affect; Aggression; Antimanic Agents; Attention Deficit and Disruptive Behavior Disorder | 2006 |
Facial emotion processing in acutely ill and euthymic patients with pediatric bipolar disorder.
Topics: Acute Disease; Adolescent; Antipsychotic Agents; Bipolar Disorder; Child; Drug Therapy, Combination; | 2007 |
2 other studies available for valproic acid and Dysthymic Disorder
| Article | Year |
|---|---|
Treating selective serotonin reuptake inhibitor-induced behavioral activation with valproate.
Topics: Adolescent; Adolescent Behavior; Behavioral Symptoms; Dysthymic Disorder; Female; Humans; Selective | 2003 |
Cognitive impairment in euthymic bipolar patients: implications for clinical and functional outcome.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Chlorpromazine; Cognition Disorders; Dysthymic Disorde | 2004 |