valproic acid has been researched along with Dyskinesia, Medication-Induced in 45 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Five patients with idiopathic generalized epilepsies (IGE) treated with lamotrigine (LTG) experienced exacerbation or de novo appearance of myoclonic jerks (MJ)." | 3.73 | Lamotrigine associated with exacerbation or de novo myoclonus in idiopathic generalized epilepsies. ( Baldy-Moulinier, M; Berramdane, M; Coubes, P; Crespel, A; Gelisse, P; Genton, P; Monicard, C, 2005) |
| " We report two cases of an adverse effect of dyskinesia and bruxism when MPH was given to children maintained on valproic acid." | 3.70 | Adverse response to methylphenidate in combination with valproic acid. ( Gara, L; Roberts, W, 2000) |
| "Valproic acid is used in first case as an antiepileptic; own clinical observance and references from the literature show other indication-fields outside of the group of cerebral fits; so Convulex was employed successfully also in the therapy of perioral dyskinesia of variable etiology and in the medical treatment of therapy-resistant pains within the bounds of Polyneuropathy-Polyneuritis Syndrome." | 3.67 | [Further therapeutic possibilities with valproic acid (Convulex)]. ( Auff, E; Holzner, F; Wessely, P, 1985) |
| "We made accelerometric recordings of the tremor induced by valproic acid." | 3.66 | Valproate tremors. ( Bauman, AW; Hammond, EJ; Karas, BJ; Wilder, BJ, 1982) |
| "Risperidone was shown to have significant anti-manic effects which was observed as early as week 1, following start of treatment." | 2.77 | Efficacy and safety of combination of risperidone and haloperidol with divalproate in patients with acute mania. ( Hsu, MC; Kuo, CC; Ouyang, WC; Yeh, IN, 2012) |
| "Aripiprazole is an effective treatment for mania in a population that includes adults, children and adolescents, although its use leads to gastrointestinal disturbances and movement disorders." | 2.49 | Aripiprazole alone or in combination for acute mania. ( Brown, R; Geddes, J; Taylor, MJ, 2013) |
| " They responded well to the reduction in dosage or to withdrawal of the apparent causing agent." | 2.49 | [Medication-related oculogyric crises: a description of four cases and a review of the literature]. ( Campistol, J; Darling, A; Perez-Duenas, B; Poo, P, 2013) |
| " Neuroleptic dosing of manic patients is probably too high and exposes patients to an unnecessary risk of side effects including tardive dyskinesia." | 2.38 | Treatment approaches for acute mania. ( Chou, JC; Sweeney, EA; Tuma, I, 1993) |
| "Among psychiatric disorders the acute symptoms of schizophrenia are exacerbated by enhanced GABA-ergic function." | 2.36 | Pharmacology of GABA. ( Meldrum, B, 1982) |
| "LTG, amantadine, and VPA were withdrawn, the remaining 2 drugs, benzhexol and compound preparation (flupentixol and melitracen), were continued to use, and the patient improved in 2." | 1.46 | Disabling tremor induced by long-term use of sodium valproate and lamotrigine: Case report. ( Chen, J; He, ZF; Rao, Z; Wang, XH; Zhou, CN, 2017) |
| "Valproic acid is a drug used for the treatment of a variety of psychiatric and neurological disorders." | 1.39 | Valproic acid-induced parkinsonism: levodopa responsiveness with dyskinesia. ( Factor, SA; Silver, M, 2013) |
| "Methylphenidate is a short-acting stimulant." | 1.39 | Methylphenidate-induced acute orofacial and extremity dyskinesia. ( Donmez, A; Isik, B; Orun, E; Sonmez, FM; Tas, T; Yilmaz, AE, 2013) |
| "Haloperidol-induced TD was also attenuated by the antioxidant, vitamin E (400 and 800 mg/kg, p." | 1.31 | Effect of Withania somnifera glycowithanolides on a rat model of tardive dyskinesia. ( Bhattacharya, D; Bhattacharya, SK; Ghosal, S; Sairam, K, 2002) |
| "The delirium was reversible when all drugs were stopped; however, dyskinesia was found to be persistent after a period of 6 months." | 1.30 | Delirium and persistent dyskinesia induced by a lithium-neuroleptic interaction. ( Berger, M; Brandt, C; Normann, C; Walden, J, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (53.33) | 18.7374 |
| 1990's | 3 (6.67) | 18.2507 |
| 2000's | 8 (17.78) | 29.6817 |
| 2010's | 10 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| He, ZF | 1 |
| Chen, J | 1 |
| Zhou, CN | 1 |
| Rao, Z | 1 |
| Wang, XH | 1 |
| Alabed, S | 1 |
| Latifeh, Y | 1 |
| Mohammad, HA | 1 |
| Bergman, H | 1 |
| Silver, M | 1 |
| Factor, SA | 1 |
| Brown, R | 1 |
| Taylor, MJ | 1 |
| Geddes, J | 1 |
| Sekhar, S | 1 |
| Kalra, B | 1 |
| Mendhekar, DN | 1 |
| Tekur, U | 1 |
| Lee, Y | 1 |
| Kim, D | 1 |
| Kim, YH | 1 |
| Lee, H | 1 |
| Lee, CJ | 1 |
| Ouyang, WC | 1 |
| Hsu, MC | 1 |
| Yeh, IN | 1 |
| Kuo, CC | 1 |
| Chung, AK | 1 |
| Yilmaz, AE | 1 |
| Donmez, A | 1 |
| Orun, E | 1 |
| Tas, T | 1 |
| Isik, B | 1 |
| Sonmez, FM | 1 |
| Darling, A | 1 |
| Poo, P | 1 |
| Perez-Duenas, B | 1 |
| Campistol, J | 1 |
| Bhattachary, SK | 1 |
| Bhattacharya, D | 2 |
| Muruganandam, AV | 1 |
| Peixoto, MF | 1 |
| Abílio, VC | 1 |
| Silva, RH | 1 |
| Frussa-Filho, R | 1 |
| Witschy, JK | 1 |
| Winter, AS | 1 |
| Luszczki, JJ | 1 |
| Antkiewicz-Michaluk, L | 1 |
| Czuczwar, SJ | 1 |
| Crespel, A | 1 |
| Genton, P | 1 |
| Berramdane, M | 1 |
| Coubes, P | 1 |
| Monicard, C | 1 |
| Baldy-Moulinier, M | 1 |
| Gelisse, P | 1 |
| Tahiroglu, AY | 1 |
| Avci, A | 1 |
| Ogawa, T | 1 |
| Nagao, T | 2 |
| Kashiwabara, K | 1 |
| Fujiwara, Y | 1 |
| Harada, T | 1 |
| Otsuki, S | 2 |
| Friis, T | 1 |
| Christensen, TR | 1 |
| Gerlach, J | 1 |
| Tegeler, J | 1 |
| Wöller, W | 1 |
| Meldrum, B | 1 |
| Hammond, EJ | 2 |
| Wilder, BJ | 2 |
| Bruni, J | 1 |
| Crowe, BM | 1 |
| Thaker, GK | 1 |
| Hare, TA | 1 |
| Tamminga, CA | 1 |
| Ames, D | 1 |
| Webber, J | 1 |
| Marsden, CD | 2 |
| Sheehy, MP | 1 |
| Nair, NP | 1 |
| Lal, S | 1 |
| Schwartz, G | 1 |
| Thavundayil, JX | 1 |
| Karas, BJ | 1 |
| Bauman, AW | 1 |
| Chou, JC | 1 |
| Tuma, I | 1 |
| Sweeney, EA | 1 |
| Kazamatsuri, H | 1 |
| Normann, C | 1 |
| Brandt, C | 1 |
| Berger, M | 1 |
| Walden, J | 1 |
| Gara, L | 1 |
| Roberts, W | 1 |
| Bhattacharya, SK | 1 |
| Sairam, K | 1 |
| Ghosal, S | 1 |
| Chien, C | 1 |
| Jung, K | 1 |
| Ross-Townsend, A | 1 |
| Ohshimo, T | 1 |
| Mitsunobu, K | 1 |
| Sato, M | 1 |
| Campanini, T | 1 |
| Catalano, A | 1 |
| De Risio, C | 1 |
| Forino, V | 1 |
| Gibson, AC | 1 |
| Price, PA | 1 |
| Parkes, JD | 1 |
| Linnoila, M | 1 |
| Viukari, M | 1 |
| Casey, DE | 1 |
| Hammerstad, JP | 1 |
| Gram, L | 1 |
| Bentsen, KD | 1 |
| Nasrallah, HA | 2 |
| Dunner, FJ | 2 |
| McCalley-Whitters, M | 2 |
| Smith, RE | 1 |
| Fisk, GG | 1 |
| York, SM | 1 |
| Monteleone, P | 1 |
| Maj, M | 1 |
| Ariano, MG | 1 |
| Iovino, M | 1 |
| Fiorenza, L | 1 |
| Steardo, L | 1 |
| Auff, E | 1 |
| Holzner, F | 1 |
| Wessely, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Aripiprazole for Pre-Existing Neuroleptic-Induced Tardive Dyskinesia: a Prospective 26-Week Observational Study[NCT00837707] | Phase 4 | 25 participants (Anticipated) | Interventional | 2008-06-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for valproic acid and Dyskinesia, Medication-Induced
| Article | Year |
|---|---|
Gamma-aminobutyric acid agonists for antipsychotic-induced tardive dyskinesia.
Topics: Antipsychotic Agents; Baclofen; Dyskinesia, Drug-Induced; GABA Agonists; gamma-Aminobutyric Acid; Hu | 2018 |
Aripiprazole alone or in combination for acute mania.
Topics: Adolescent; Adult; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Child; Dr | 2013 |
[Medication-related oculogyric crises: a description of four cases and a review of the literature].
Topics: Adolescent; Anticonvulsants; Antipsychotic Agents; Aripiprazole; Child; Child Behavior Disorders; Ch | 2013 |
Pharmacology of GABA.
Topics: 4-Aminobutyrate Transaminase; Anxiety Disorders; Autonomic Nervous System; Barbiturates; Benzodiazep | 1982 |
Central actions of valproic acid in man and in experimental models of epilepsy.
Topics: 4-Aminobutyrate Transaminase; Action Potentials; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; | 1981 |
GABA system: clinical research and treatment of tardive dyskinesia.
Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyski | 1983 |
Treatment approaches for acute mania.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Dyskinesia, Drug-Induced; Fe | 1993 |
[Tardive dyskinesia--diagnosis and treatment].
Topics: Clonidine; Diagnosis, Differential; Dyskinesia, Drug-Induced; Humans; Middle Aged; Psychotropic Drug | 1993 |
Valproate: an updated review.
Topics: Abnormalities, Drug-Induced; Brain Diseases; Chemical and Drug Induced Liver Injury; Coma; Dyskinesi | 1985 |
10 trials available for valproic acid and Dyskinesia, Medication-Induced
| Article | Year |
|---|---|
Efficacy of sodium valproate and haloperidol in the management of acute mania: a randomized open-label comparative study.
Topics: Adolescent; Adult; Antimanic Agents; Bipolar Disorder; Dyskinesia, Drug-Induced; Female; Haloperidol | 2010 |
Efficacy and safety of combination of risperidone and haloperidol with divalproate in patients with acute mania.
Topics: Acute Disease; Adolescent; Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Body Wei | 2012 |
GABA system: clinical research and treatment of tardive dyskinesia.
Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyski | 1983 |
GABA and movement disorders.
Topics: Anticonvulsants; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; | 1981 |
Efficacies of agents related to GABA, dopamine, and acetylcholine in the treatment of tardive dyskinesia [proceedings].
Topics: Acetylcholine; Clinical Trials as Topic; Deanol; Dopamine; Dyskinesia, Drug-Induced; Ethanolamines; | 1978 |
Sodium valproate in the treatment of levodopa-induced dyskinesia.
Topics: Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; M | 1978 |
Pharmacologic probes of neurotransmitter systems in tardive dyskinesia: implications for clinical management.
Topics: 5-Hydroxytryptophan; Adult; Aged; Choline; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamin | 1986 |
The effect of sodium valproate on tardive dyskinesia--revisited.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans | 1987 |
Prolactin response to sodium valproate in schizophrenics with and without tardive dyskinesia.
Topics: Adult; Aged; Dyskinesia, Drug-Induced; Humans; Male; Middle Aged; Prolactin; Psychiatric Status Rati | 1988 |
A placebo-controlled trial of valproate in tardive dyskinesia.
Topics: Adult; Aged; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; | 1985 |
27 other studies available for valproic acid and Dyskinesia, Medication-Induced
| Article | Year |
|---|---|
Disabling tremor induced by long-term use of sodium valproate and lamotrigine: Case report.
Topics: Amantadine; Anticonvulsants; Antiparkinson Agents; Dyskinesia, Drug-Induced; Dyskinesias; Humans; La | 2017 |
Valproic acid-induced parkinsonism: levodopa responsiveness with dyskinesia.
Topics: Adult; Aged; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Diseas | 2013 |
Improvement of pentylenetetrazol-induced learning deficits by valproic acid in the adult zebrafish.
Topics: Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Brain; Dose-Response Relationship, D | 2010 |
Atypical presentation of tardive dyskinesia associated with risperidone long-acting injection as maintenance treatment in bipolar affective disorder: a case report.
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Delayed-Action Preparations; Drug Therapy, | 2012 |
Methylphenidate-induced acute orofacial and extremity dyskinesia.
Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; C | 2013 |
Effect of Emblica officinalis tannoids on a rat model of tardive dyskinesia.
Topics: Animals; Anti-Dyskinesia Agents; Anticonvulsants; Antioxidants; Brain; Disease Models, Animal; Dyski | 2000 |
Effects of valproic acid on an animal model of tardive dyskinesia.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, | 2003 |
Improvement in tardive dyskinesia with aripiprazole use.
Topics: Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Drug Interactions; Drug Therapy, Combination; | 2005 |
1-Methyl-1,2,3,4-tetrahydroisoquinoline enhances the anticonvulsant action of carbamazepine and valproate in the mouse maximal electroshock seizure model.
Topics: Animals; Anticonvulsants; Carbamazepine; Dopamine Antagonists; Dyskinesia, Drug-Induced; Electroshoc | 2006 |
Lamotrigine associated with exacerbation or de novo myoclonus in idiopathic generalized epilepsies.
Topics: Adult; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Epilepsie | 2005 |
Polypharmacy and EPS in a child; a case report.
Topics: Attention Deficit Disorder with Hyperactivity; Benztropine; Bipolar Disorder; Child; Comorbidity; Do | 2007 |
Tardive dyskinesia and neurotransmitters: effects of sodium valproate, cyproheptadine, oxypertine, hydroxyzine pamoate and Ca-hopantenate on monoamine metabolites, cyclic nucleotides and gamma-aminobutyric acid in human cerebrospinal fluid.
Topics: Adult; Aged; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Homovanillic | 1984 |
Sodium valproate and biperiden in neuroleptic-induced akathisia, parkinsonism and hyperkinesia. A double-blind cross-over study with placebo.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Biperiden; Double-Blind Method; Drug Therapy, Combina | 1983 |
[Therapeutic measures in tardive dyskinesia].
Topics: Age Factors; Amantadine; Antipsychotic Agents; Baclofen; Benzodiazepines; Bromocriptine; Deanol; Dih | 1983 |
Symptom control in tardive dyskinesia.
Topics: Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Valpr | 1983 |
Sodium valproate and tardive dyskinesia.
Topics: Aged; Dyskinesia, Drug-Induced; Female; Humans; Valproic Acid | 1984 |
Effect of sodium valproate and baclofen in tardive dyskinesia: clinical and neuroendocrine studies.
Topics: Adult; Baclofen; Chronic Disease; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Halop | 1980 |
Valproate tremors.
Topics: Adolescent; Adult; Diagnosis, Differential; Dyskinesia, Drug-Induced; Humans; Middle Aged; Parkinson | 1982 |
Delirium and persistent dyskinesia induced by a lithium-neuroleptic interaction.
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Delirium; Dyskinesia, Drug-Induced; Female | 1998 |
Adverse response to methylphenidate in combination with valproic acid.
Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Bruxism; Central Nervous System Stim | 2000 |
Effect of Withania somnifera glycowithanolides on a rat model of tardive dyskinesia.
Topics: Animals; Anti-Dyskinesia Agents; Anticonvulsants; Antioxidants; Disease Models, Animal; Dyskinesia, | 2002 |
Cerebrospinal fluid monoamine metabolites and cyclic nucleotides in chronic schizophrenic patients with tardive dyskinesia or drug-induced tremor.
Topics: Adult; Chronic Disease; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Ho | 1979 |
[Tardive dyskinesia. Synthetic-critical review and case contribution].
Topics: Adult; Aged; Baclofen; Dyskinesia, Drug-Induced; Female; Humans; Iatrogenic Disease; Male; Mental Di | 1977 |
Sodium valproate and tardive dyskinesia.
Topics: Adult; Aged; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Schiz | 1978 |
Sodium valproate and tardive dyskinesia.
Topics: Aged; Dyskinesia, Drug-Induced; Humans; Research Design; Valproic Acid | 1979 |
Sodium valproate in tardive dyskinesia.
Topics: Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Humans; Male; Middle Aged; Valproic Acid | 1979 |
[Further therapeutic possibilities with valproic acid (Convulex)].
Topics: Aged; Blepharospasm; Dyskinesia, Drug-Induced; Female; Foot Diseases; Humans; Male; Middle Aged; Myo | 1985 |