valproic acid has been researched along with Dizzyness in 12 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One-hundred eighty patients with partial or idiopathic generalized nonabsence epilepsy, aged 6 to 65 years, requiring initiation of treatment with carbamazepine (CBZ), valproate (VPA), phenytoin (PHT), phenobarbital (PB), or primidone (PRM) were randomly allocated to two groups according to an open, prospective parallel-group design." | 5.09 | A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. The Italian TDM Study Group in Epilepsy. ( Bartoli, A; Cian, P; Fattore, C; Gatti, G; Jannuzzi, G; Monaco, F; Perucca, E, 2000) |
| " On the other hand, patients with divalproex exhibited significantly higher risk of nausea compared to those with placebo, topiramate, propranolol, gabapentin and amitriptyline." | 4.95 | Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis. ( He, A; Li, C; Song, D; Zhang, L, 2017) |
| " The small decreases in mean valproic acid Cmax and AUC0-tau observed during the concomitant administration of tiagabine and valproate are probably of limited clinical importance, given the broad therapeutic range of valproate (50-100 microg/mL)." | 2.69 | Lack of a clinically significant pharmacokinetic drug interaction between tiagabine and valproate. ( Boellner, SW; Granneman, GR; Guenther, HJ; Gustavson, LE; Sommerville, KW; Witt, GF, 1998) |
| " Two analyses of adverse events are presented: tolerability and safety." | 2.69 | Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study. ( Bernstein, P; Faught, RE; Holmes, GL; Magnus-Miller, L; McLean, MJ; Morrell, MJ; Privitera, MD; Rose-Legatt, A; Willmore, LJ, 1999) |
| " The adverse effect (AE) profile of this combination needs clarification." | 2.69 | Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS) Group. ( Faught, E; French, J; Harden, C; Jacobson, M; Montouris, G; Morris, G; Rosenfeld, W, 1999) |
| "In all the patients with cerebral infarction, the current arrows exhibited the similar pattern as the normal subjects." | 1.31 | Cortical functional abnormality assessed by auditory-evoked magnetic fields and therapeutic approach in patients with chronic dizziness. ( Kandori, A; Miyashita, K; Murakami, M; Naritomi, H; Oe, H; Tsukada, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Androsova, G | 1 |
| Krause, R | 1 |
| Borghei, M | 1 |
| Wassenaar, M | 1 |
| Auce, P | 1 |
| Avbersek, A | 1 |
| Becker, F | 1 |
| Berghuis, B | 1 |
| Campbell, E | 1 |
| Coppola, A | 1 |
| Francis, B | 1 |
| Wolking, S | 1 |
| Cavalleri, GL | 1 |
| Craig, J | 1 |
| Delanty, N | 1 |
| Koeleman, BPC | 1 |
| Kunz, WS | 1 |
| Lerche, H | 1 |
| Marson, AG | 1 |
| Sander, JW | 1 |
| Sills, GJ | 1 |
| Striano, P | 1 |
| Zara, F | 1 |
| Sisodiya, SM | 1 |
| Depondt, C | 1 |
| He, A | 1 |
| Song, D | 1 |
| Zhang, L | 1 |
| Li, C | 1 |
| Thibault, M | 1 |
| Blume, WT | 1 |
| Saint-Hilaire, JM | 1 |
| Zakhari, R | 1 |
| Sommerville, KW | 2 |
| Oe, H | 1 |
| Kandori, A | 1 |
| Murakami, M | 1 |
| Miyashita, K | 1 |
| Tsukada, K | 1 |
| Naritomi, H | 1 |
| Sandson, NB | 1 |
| Marcucci, C | 1 |
| Bourke, DL | 1 |
| Smith-Lamacchia, R | 1 |
| Thibodeau, LG | 1 |
| Ferrera, PC | 1 |
| Gustavson, LE | 1 |
| Boellner, SW | 1 |
| Witt, GF | 1 |
| Guenther, HJ | 1 |
| Granneman, GR | 1 |
| McLean, MJ | 1 |
| Morrell, MJ | 1 |
| Willmore, LJ | 1 |
| Privitera, MD | 1 |
| Faught, RE | 1 |
| Holmes, GL | 1 |
| Magnus-Miller, L | 1 |
| Bernstein, P | 1 |
| Rose-Legatt, A | 1 |
| Faught, E | 1 |
| Morris, G | 1 |
| Jacobson, M | 1 |
| French, J | 1 |
| Harden, C | 1 |
| Montouris, G | 1 |
| Rosenfeld, W | 1 |
| Matsuo, F | 1 |
| Jannuzzi, G | 1 |
| Cian, P | 1 |
| Fattore, C | 1 |
| Gatti, G | 1 |
| Bartoli, A | 1 |
| Monaco, F | 1 |
| Perucca, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Study on Long-term Outcome and Potential Usefulness fo an Intervention Aimed at Reducing Adverse Effects in Patients With Refractory Epilepsy[NCT03939507] | 1,000 participants (Actual) | Interventional | 2006-11-06 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for valproic acid and Dizzyness
| Article | Year |
|---|---|
Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis.
Topics: Adult; Amines; Amitriptyline; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizziness; Female; Fruct | 2017 |
Lamotrigine.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Diplopia; Dizziness; D | 1999 |
5 trials available for valproic acid and Dizzyness
| Article | Year |
|---|---|
Divalproex extended-release versus the original divalproex tablet: results of a randomized, crossover study of well-controlled epileptic patients with primary generalized seizures.
Topics: Adolescent; Adult; Analysis of Variance; Asthenia; Child; Cross-Over Studies; Delayed-Action Prepara | 2002 |
Lack of a clinically significant pharmacokinetic drug interaction between tiagabine and valproate.
Topics: Adolescent; Adult; Anticonvulsants; Dizziness; Drug Interactions; Drug Monitoring; Drug Therapy, Com | 1998 |
Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study.
Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Asthenia; Carbamazepine; Cycl | 1999 |
Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS) Group.
Topics: Adolescent; Adult; Child; Dizziness; Drug Eruptions; Drug Hypersensitivity; Drug Therapy, Combinatio | 1999 |
A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. The Italian TDM Study Group in Epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dizziness; Drug Administration Sched | 2000 |
5 other studies available for valproic acid and Dizzyness
| Article | Year |
|---|---|
Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Ataxia; Benzodiazepines; Carbamazepine; Clobazam; | 2017 |
Cortical functional abnormality assessed by auditory-evoked magnetic fields and therapeutic approach in patients with chronic dizziness.
Topics: Acoustic Stimulation; Aged; Anticonvulsants; Auditory Cortex; Auditory Diseases, Central; Brain Mapp | 2002 |
An interaction between aspirin and valproate: the relevance of plasma protein displacement drug-drug interactions.
Topics: Aged; Anticonvulsants; Aspirin; Blood Proteins; Dizziness; Drug Interactions; Drug Monitoring; Human | 2006 |
Nonconvulsive status epilepticus.
Topics: Anticonvulsants; Dizziness; Electroencephalography; Emergency Service, Hospital; Epilepsy, Tonic-Clo | 1997 |
Valproate and other anticonvulsants for psychiatric disorders.
Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Bipolar | 2000 |