Page last updated: 2024-10-26

valproic acid and Disruptive, Impulse Control, and Conduct Disorders

valproic acid has been researched along with Disruptive, Impulse Control, and Conduct Disorders in 14 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Disruptive, Impulse Control, and Conduct Disorders: Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.

Research Excerpts

ExcerptRelevanceReference
"Forty-two subjects with DSM-IV-defined pathological gambling entered a 14-week single-blind trial with lithium (N = 23) or valproate (N = 19)."9.10Lithium and valproate treatment of pathological gambling: a randomized single-blind study. ( Hollander, E; Pallanti, S; Quercioli, L; Sood, E, 2002)
"Forty-two subjects with DSM-IV-defined pathological gambling entered a 14-week single-blind trial with lithium (N = 23) or valproate (N = 19)."5.10Lithium and valproate treatment of pathological gambling: a randomized single-blind study. ( Hollander, E; Pallanti, S; Quercioli, L; Sood, E, 2002)
"The objectives of this study were to determine whether autistic children taking levetiracetam (1) showed improvement in the areas of aggression, impulsivity, hyperkinesis, and mood instability, and (2) showed a nootropic response."5.10Levetiracetam in autistic children: an open-label study. ( Rugino, TA; Samsock, TC, 2002)
"In the treatment of kleptomania, only naltrexone was effective."2.82Pharmacotherapy of impulse control disorders: A systematic review. ( Maaz, M; Naidoo, Y; Naufal, R; Tahir, R; Tahir, T; Wong, MM, 2022)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's6 (42.86)29.6817
2010's5 (35.71)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Tahir, T1
Wong, MM1
Maaz, M1
Naufal, R1
Tahir, R1
Naidoo, Y1
Hlal, H1
Barrimi, M1
Kettani, N1
Rammouz, I1
Aalouane, R1
Santos-Cubiñá, J1
Torres-Rodríguez, A1
Castaing-Lespier, PA1
Sabaté, N1
Torres-Martin, A1
Carlo, S1
Coccaro, EF1
Lee, R1
Breen, EC1
Irwin, MR1
Hicks, CW1
Pandya, MM1
Itin, I1
Fernandez, HH1
Sriram, A1
Ward, HE1
Hassan, A1
Iyer, S1
Foote, KD1
Rodriguez, RL1
McFarland, NR1
Okun, MS1
Pallanti, S2
Quercioli, L1
Sood, E1
Hollander, E2
Rugino, TA1
Samsock, TC1
Yehya, N1
Saldarini, CT1
Koski, ME1
Davanzo, P1
DeCaria, CM1
Grant, JE1
Urpe, M1
Kmetz, GF1
McElroy, SL1
Collins, DJ1
Donovan, SJ1
Stewart, JW1
Nunes, EV1
Quitkin, FM1
Parides, M1
Daniel, W1
Susser, E1
Klein, DF1
Buchalter, EN1
Lantz, MS1
Szymanski, HV1
Olympia, J1

Reviews

1 review available for valproic acid and Disruptive, Impulse Control, and Conduct Disorders

ArticleYear
Pharmacotherapy of impulse control disorders: A systematic review.
    Psychiatry research, 2022, Volume: 311

    Topics: Antidepressive Agents; Disruptive, Impulse Control, and Conduct Disorders; Fluoxetine; Humans; Valpr

2022

Trials

4 trials available for valproic acid and Disruptive, Impulse Control, and Conduct Disorders

ArticleYear
Inflammatory markers and chronic exposure to fluoxetine, divalproex, and placebo in intermittent explosive disorder.
    Psychiatry research, 2015, Oct-30, Volume: 229, Issue:3

    Topics: Adult; Aggression; Biomarkers; C-Reactive Protein; Disruptive, Impulse Control, and Conduct Disorder

2015
Lithium and valproate treatment of pathological gambling: a randomized single-blind study.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:7

    Topics: Anticonvulsants; Disruptive, Impulse Control, and Conduct Disorders; Drug Administration Schedule; F

2002
Levetiracetam in autistic children: an open-label study.
    Journal of developmental and behavioral pediatrics : JDBP, 2002, Volume: 23, Issue:4

    Topics: Aggression; Anticonvulsants; Autistic Disorder; Cetirizine; Child; Child Behavior Disorders; Child,

2002
Divalproex treatment for youth with explosive temper and mood lability: a double-blind, placebo-controlled crossover design.
    The American journal of psychiatry, 2000, Volume: 157, Issue:5

    Topics: Adolescent; Ambulatory Care; Anticonvulsants; Attention Deficit and Disruptive Behavior Disorders; C

2000

Other Studies

9 other studies available for valproic acid and Disruptive, Impulse Control, and Conduct Disorders

ArticleYear
["Factitious disorder and skin picking: Clinical approach". A case report].
    L'Encephale, 2014, Volume: 40, Issue:2

    Topics: Alprazolam; Anxiety Disorders; Comorbidity; Diagnosis, Differential; Disruptive, Impulse Control, an

2014
Exacerbation of mood symptoms associated to primary and secondary carnitine deficiency: a case report.
    Boletin de la Asociacion Medica de Puerto Rico, 2013, Volume: 105, Issue:3

    Topics: Adult; Antidepressive Agents; Antimanic Agents; Attention Deficit Disorder with Hyperactivity; Benzo

2013
Valproate for the treatment of medication-induced impulse-control disorders in three patients with Parkinson's disease.
    Parkinsonism & related disorders, 2011, Volume: 17, Issue:5

    Topics: Adult; Anticonvulsants; Antiparkinson Agents; Disruptive, Impulse Control, and Conduct Disorders; Hu

2011
Valproate as a treatment for dopamine dysregulation syndrome (DDS) in Parkinson's disease.
    Journal of neurology, 2013, Volume: 260, Issue:2

    Topics: Aged; Aged, 80 and over; Akathisia, Drug-Induced; Anticonvulsants; Carbidopa; Disruptive, Impulse Co

2013
Valproate-induced hyperammonemic encephalopathy.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2004, Volume: 43, Issue:8

    Topics: Aggression; Anticonvulsants; Attention Deficit and Disruptive Behavior Disorders; Child; Diagnosis,

2004
Reliability and validity of the pathological gambling adaptation of the Yale-Brown Obsessive-Compulsive Scale (PG-YBOCS).
    Journal of gambling studies, 2005,Winter, Volume: 21, Issue:4

    Topics: Adult; Disruptive, Impulse Control, and Conduct Disorders; Female; Fluvoxamine; Gambling; Humans; Li

2005
Response of kleptomania and mixed mania to valproate.
    The American journal of psychiatry, 1997, Volume: 154, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Antimanic Agents; Bipolar Disorder; Comorbidity; Di

1997
Treatment of impulsivity and aggression in a patient with vascular dementia.
    Geriatrics, 2001, Volume: 56, Issue:2

    Topics: Aged; Aggression; Antimanic Agents; Dementia, Vascular; Disruptive, Impulse Control, and Conduct Dis

2001
Divalproex in posttraumatic stress disorder.
    The American journal of psychiatry, 1991, Volume: 148, Issue:8

    Topics: Adult; Aggression; Disruptive, Impulse Control, and Conduct Disorders; Humans; Male; Stress Disorder

1991