Page last updated: 2024-10-26

valproic acid and Diseases in Twins

valproic acid has been researched along with Diseases in Twins in 11 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Diseases in Twins: Disorders affecting TWINS, one or both, at any age.

Research Excerpts

ExcerptRelevanceReference
"Metopic craniosynostosis may be an adverse effect of valproic acid exposed fetus."1.31[Metopic craniosynostosis, probable effect of intrauterine exposure to maternal valproate treatment]. ( Bensouda, B; Bruel, H; Chabrolle, JP; Degre, S; Ickowicz, V; Poinsot, J; Simon, A, 2001)
"A possible causal relationship between autism and absence seizures in these children is explored."1.30Valproic acid treatment of epilepsy in autistic twins. ( Blair, JL; Childs, JA, 1997)
"Myoclonic dystonia is a rare disorder that occurs in an hereditary and a sporadic form."1.28Myoclonic dystonia. ( Friedman, JH; Pueschel, SM; Shetty, T, 1992)
" Furthermore, long-term administration (over a year) of high doses of the agent (up to 2,400 mg per day; 92 mg per kilogram per day) did not seem to alter the slow progression of their disease."1.26Long-term treatment of juvenile Huntington's chorea with dipropylacetic acid. ( Bachman, DS; Butler, IJ; McKhann, GM, 1977)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's5 (45.45)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Markovic, J1
Plestic, S1
Kostic, J1
Petty, SJ1
Kantor, S1
Lawrence, KM1
Berkovic, SF1
Collins, M1
Hill, KD1
Makovey, J1
Sambrook, PN1
O'Brien, TJ1
Wark, JD1
Klein, KM1
Hamer, HM1
Reis, J1
Schmidtke, J1
Oertel, WH1
Theisen, FM1
Hebebrand, J1
Rosenow, F1
Vojvoda, D1
Grimmell, K1
Sernyak, M1
Mazure, CM1
Hockey, A1
Bower, C1
Goldblatt, J1
Knowles, S1
Childs, JA1
Blair, JL1
Chabrolle, JP1
Bensouda, B1
Bruel, H1
Simon, A1
Poinsot, J1
Ickowicz, V1
Degre, S1
Bachman, DS1
Butler, IJ1
McKhann, GM1
Pueschel, SM1
Friedman, JH1
Shetty, T1
Skarpa, D1
Barisić, N1
Bulat, M1
Campostrini, R1
Zaccara, G1
Rossi, L1
Paganini, M1
Dorigotti, A1
Zappoli, R1

Other Studies

11 other studies available for valproic acid and Diseases in Twins

ArticleYear
Concordant response to pharmacotherapy in monozygotic twins with schizoaffective disorder.
    European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:23

    Topics: Affect; Alopecia; Antipsychotic Agents; Diseases in Twins; Drug Therapy, Combination; Emotions; Huma

2013
Weight and fat distribution in patients taking valproate: a valproate-discordant gender-matched twin and sibling pair study.
    Epilepsia, 2014, Volume: 55, Issue:10

    Topics: Abdominal Fat; Absorptiometry, Photon; Adult; Anticonvulsants; Blood Pressure; Body Composition; Bod

2014
Weight change in monozygotic twins treated with valproate.
    Obesity research, 2005, Volume: 13, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Child, Preschool; Diseases in Twins; Epilepsy; Female; Humans; M

2005
Monozygotic twins concordant for response to clozapine.
    Lancet (London, England), 1996, Jan-06, Volume: 347, Issue:8993

    Topics: Adult; Antipsychotic Agents; Clozapine; Diseases in Twins; Drug Therapy, Combination; Humans; Male;

1996
Fetal valproate embryopathy in twins: genetic modification of the response to a teratogen.
    Birth defects original article series, 1996, Volume: 30, Issue:1

    Topics: Abnormalities, Multiple; Adult; Anticonvulsants; Diseases in Twins; Epilepsy; Female; Humans; Infant

1996
Valproic acid treatment of epilepsy in autistic twins.
    The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 1997, Volume: 29, Issue:4

    Topics: Anticonvulsants; Autistic Disorder; Child, Preschool; Developmental Disabilities; Diseases in Twins;

1997
[Metopic craniosynostosis, probable effect of intrauterine exposure to maternal valproate treatment].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2001, Volume: 8, Issue:12

    Topics: Abnormalities, Drug-Induced; Craniosynostoses; Diseases in Twins; Epilepsy, Generalized; Female; Hum

2001
Long-term treatment of juvenile Huntington's chorea with dipropylacetic acid.
    Neurology, 1977, Volume: 27, Issue:2

    Topics: Child; Diseases in Twins; Female; Half-Life; Humans; Huntington Disease; Valerates; Valproic Acid

1977
Myoclonic dystonia.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1992, Volume: 8, Issue:2

    Topics: Adult; Biopsy; Cerebellum; Diseases in Twins; Drug Therapy, Combination; Dystonia; Epilepsies, Myocl

1992
Monozygotic twins with centrotemporal EEG spikes--differences in clinical expression and effects of valproate therapy.
    The New England journal of medicine, 1991, Jun-20, Volume: 324, Issue:25

    Topics: Child; Diseases in Twins; Electroencephalography; Epilepsy, Absence; Female; Humans; Twins, Monozygo

1991
Valproate-induced hyperammonaemia in two epileptic identical twins.
    Journal of neurology, 1985, Volume: 232, Issue:3

    Topics: Adult; Ammonia; Diseases in Twins; Drug Therapy, Combination; Electroencephalography; Epilepsy, Abse

1985