Page last updated: 2024-10-26

valproic acid and Disbacteriosis

valproic acid has been researched along with Disbacteriosis in 5 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"We have investigated the species richness and microbial composition in a valproic acid (VPA)-induced rat model autism."7.88The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism. ( Horton-Sparks, K; Hull, V; Li, RW; Liu, F; Martínez-Cerdeño, V, 2018)
"Melatonin is an endogenous hormone and can restore gut microbial dysbiosis under various disease conditions."5.72Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism. ( Cui, Y; Li, XG; Liu, W; Liu, X; Qiu, B; Wang, X; Xiang, G; Yu, M; Zhang, D; Zhang, Y, 2022)
"We have investigated the species richness and microbial composition in a valproic acid (VPA)-induced rat model autism."3.88The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism. ( Horton-Sparks, K; Hull, V; Li, RW; Liu, F; Martínez-Cerdeño, V, 2018)
"However, the development of the autism-related gut microbiota and its relationship with intestinal dysfunction in ASD remain unclear."1.72Congenitally underdeveloped intestine drives autism-related gut microbiota and behavior. ( Chen, M; Cheng, M; Gao, X; He, Y; Li, H; Li, J; Li, Z; Liu, F; Meng, F; Qing, W; Shen, W; Shi, Y; Wang, H; Wang, Q; Wu, F; Zeng, N; Zhou, H, 2022)
"Melatonin is an endogenous hormone and can restore gut microbial dysbiosis under various disease conditions."1.72Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism. ( Cui, Y; Li, XG; Liu, W; Liu, X; Qiu, B; Wang, X; Xiang, G; Yu, M; Zhang, D; Zhang, Y, 2022)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Li, J1
Wang, H1
Qing, W1
Liu, F2
Zeng, N1
Wu, F1
Shi, Y1
Gao, X1
Cheng, M1
Li, H1
Shen, W1
Meng, F1
He, Y1
Chen, M1
Li, Z1
Zhou, H1
Wang, Q1
Liu, X3
Cui, Y3
Zhang, Y3
Xiang, G3
Yu, M3
Wang, X3
Qiu, B3
Li, XG3
Liu, W3
Zhang, D3
Wang, J1
Cao, Y1
Hou, W1
Bi, D1
Yin, F1
Gao, Y1
Huang, D1
Li, Y1
Cao, Z1
Yan, Y1
Zhao, J1
Kong, D1
Lv, X1
Huang, L1
Zhong, H1
Wu, C1
Chen, Q1
Yang, R1
Wei, Q1
Qin, H1
Lim, JS1
Lim, MY1
Choi, Y1
Ko, G1
Horton-Sparks, K1
Hull, V1
Li, RW1
Martínez-Cerdeño, V1

Other Studies

5 other studies available for valproic acid and Disbacteriosis

ArticleYear
Congenitally underdeveloped intestine drives autism-related gut microbiota and behavior.
    Brain, behavior, and immunity, 2022, Volume: 105

    Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Dysbiosis; Gastrointestinal Diseases; Gastroin

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Rescue of social deficits by early-life melatonin supplementation through modulation of gut microbiota in a murine model of autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Akkermansia; Animals; Autism Spectrum Disorder; Autistic Disorder; Dietary Supplements; Disease Mode

2022
Fecal microbiota transplantation improves VPA-induced ASD mice by modulating the serotonergic and glutamatergic synapse signaling pathways.
    Translational psychiatry, 2023, Jan-21, Volume: 13, Issue:1

    Topics: Animals; Autism Spectrum Disorder; Dysbiosis; Fecal Microbiota Transplantation; Mice; Signal Transdu

2023
Modeling environmental risk factors of autism in mice induces IBD-related gut microbial dysbiosis and hyperserotonemia.
    Molecular brain, 2017, 04-20, Volume: 10, Issue:1

    Topics: Animals; Autistic Disorder; Bacteria; Biodiversity; Diet; Dysbiosis; Environment; Gastrointestinal M

2017
The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism.
    Molecular autism, 2018, Volume: 9

    Topics: Animals; Autistic Disorder; Bacterial Typing Techniques; Disease Models, Animal; Dysbiosis; Gastroin

2018