valproic acid has been researched along with Deficiency, Vitamin D in 12 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study is to evaluate if valproate (VPA) and levetiracetam (LEV) as monotherapy are associated with vitamin D deficiency among children with epilepsy." | 7.88 | Vitamin D deficiency in children with epilepsy taking valproate and levetiracetam as monotherapy. ( Aguilera-Albesa, S; Durá-Travé, T; Gallinas-Victoriano, F; Malumbres-Chacón, M; Moreno-Gónzalez, P; Yoldi-Petri, ME, 2018) |
| "To assess the effect of monotherapy with Carbamazepine (CBZ) and Sodium valproate (VPA) on serum 25-OH Vitamin D levels in children with epilepsy compared to controls." | 7.88 | Vitamin D Deficiency in Ambulant Children on Carbamazepine or Sodium Valproate Monotherapy. ( Devadathan, K; Mohammed Kunju, PA; Muthubeevi, S; Pillai, JP; Sasidharan, B; Sreedharan, M; Vasumathy Amma, MA, 2018) |
| "Our aim was to investigate any adverse effects of long-term valproic acid (VPA) therapy on bone biochemical markers in ambulatory children and adolescents with epilepsy, and the possible benefits of vitamin D supplementation on the same markers." | 3.91 | Vitamin D supplementation and bone markers in ambulatory children on long-term valproic acid therapy. A prospective interventional study. ( Challa, A; Cholevas, V; Nakou, I; Papassava, M; Siomou, E; Tzoufi, M, 2019) |
| "The aim of this study is to evaluate if valproate (VPA) and levetiracetam (LEV) as monotherapy are associated with vitamin D deficiency among children with epilepsy." | 3.88 | Vitamin D deficiency in children with epilepsy taking valproate and levetiracetam as monotherapy. ( Aguilera-Albesa, S; Durá-Travé, T; Gallinas-Victoriano, F; Malumbres-Chacón, M; Moreno-Gónzalez, P; Yoldi-Petri, ME, 2018) |
| "To assess the effect of monotherapy with Carbamazepine (CBZ) and Sodium valproate (VPA) on serum 25-OH Vitamin D levels in children with epilepsy compared to controls." | 3.88 | Vitamin D Deficiency in Ambulant Children on Carbamazepine or Sodium Valproate Monotherapy. ( Devadathan, K; Mohammed Kunju, PA; Muthubeevi, S; Pillai, JP; Sasidharan, B; Sreedharan, M; Vasumathy Amma, MA, 2018) |
| "Therefore, in children with a seizure disorder on long-term valproate therapy, 25-OH-Vit D levels should be monitored and appropriate supplementation implemented if levels are deficient." | 2.61 | Valproate decreases vitamin D levels in pediatric patients with epilepsy. ( Chen, F; Guo, H; Hu, Y; Jing, X; Li, G; Lu, XP; Sun, F; Sun, J; Wang, T; Wen, X; Xu, Z, 2019) |
| "For patients with mental retardation or developmental delay, 25(OH)D3 levels were lower than the levels in patients with normal intelligence quotient levels (p=0." | 1.40 | Vitamin D levels in children and adolescents with antiepileptic drug treatment. ( Baek, JH; Eun, BL; Kim, GH; Kim, MK; Seo, YH, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, S | 1 |
| Qi, J | 1 |
| Sun, Y | 1 |
| Gao, X | 1 |
| Ma, J | 1 |
| Zhao, S | 1 |
| Mishra, S | 1 |
| Mishra, D | 1 |
| Mahajan, B | 1 |
| Mantan, M | 1 |
| Khan, AM | 1 |
| Sharma, A | 1 |
| Sinha, S | 1 |
| Narang, A | 1 |
| Chouhan, DK | 1 |
| Gupta, S | 1 |
| Durá-Travé, T | 1 |
| Gallinas-Victoriano, F | 1 |
| Malumbres-Chacón, M | 1 |
| Moreno-Gónzalez, P | 1 |
| Aguilera-Albesa, S | 1 |
| Yoldi-Petri, ME | 1 |
| Sreedharan, M | 1 |
| Devadathan, K | 1 |
| Mohammed Kunju, PA | 1 |
| Sasidharan, B | 1 |
| Pillai, JP | 1 |
| Vasumathy Amma, MA | 1 |
| Muthubeevi, S | 1 |
| Bolland, MJ | 1 |
| Avenell, A | 1 |
| Gamble, G | 1 |
| Grey, A | 1 |
| Attilakos, A | 1 |
| Tsirouda, M | 1 |
| Dinopoulos, A | 1 |
| Prasouli, A | 1 |
| Garoufi, A | 1 |
| Xu, Z | 1 |
| Jing, X | 1 |
| Li, G | 1 |
| Sun, J | 1 |
| Guo, H | 1 |
| Hu, Y | 1 |
| Sun, F | 1 |
| Wen, X | 1 |
| Chen, F | 1 |
| Wang, T | 1 |
| Lu, XP | 1 |
| Papassava, M | 1 |
| Nakou, I | 1 |
| Siomou, E | 1 |
| Cholevas, V | 1 |
| Challa, A | 1 |
| Tzoufi, M | 1 |
| Awa, HD | 1 |
| Chelo, D | 1 |
| Kinkela, MN | 1 |
| Ndombo, PO | 1 |
| Baek, JH | 1 |
| Seo, YH | 1 |
| Kim, GH | 1 |
| Kim, MK | 1 |
| Eun, BL | 1 |
| Seymour, HM | 1 |
| Glendenning, P | 1 |
1 review available for valproic acid and Deficiency, Vitamin D
| Article | Year |
|---|---|
Valproate decreases vitamin D levels in pediatric patients with epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Humans; Valproic Acid | 2019 |
1 trial available for valproic acid and Deficiency, Vitamin D
| Article | Year |
|---|---|
Effect of Daily Vitamin D Supplementation on Serum Vitamin D Levels in Children with Epilepsy Receiving Sodium Valproate Monotherapy: A Randomized, Controlled Trial.
Topics: Alkaline Phosphatase; Calcium; Child; Dietary Supplements; Epilepsy; Humans; Parathyroid Hormone; Ph | 2023 |
10 other studies available for valproic acid and Deficiency, Vitamin D
| Article | Year |
|---|---|
An integrated RNA-Seq and network study reveals that valproate inhibited progesterone production in human granulosa cells.
Topics: Cell Line, Tumor; Cell Survival; Cholesterol Side-Chain Cleavage Enzyme; Female; Gene Expression Pro | 2021 |
Waddling Gait: A complication of valproate therapy and a thought beyond vitamin D deficiency.
Topics: Adolescent; Anticonvulsants; Antipsychotic Agents; Drug Therapy, Combination; Epilepsy, Absence; Fem | 2020 |
Vitamin D deficiency in children with epilepsy taking valproate and levetiracetam as monotherapy.
Topics: Adolescent; Child; Cross-Sectional Studies; Epilepsy; Female; Humans; Levetiracetam; Male; Prevalenc | 2018 |
Vitamin D Deficiency in Ambulant Children on Carbamazepine or Sodium Valproate Monotherapy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child, Preschool; Cross-Sec | 2018 |
Reader response: Expression of Concern: Does compensatory hyperparathyroidism predispose to ischemic stroke? Decreased bone mass and increased bone turnover with valproate therapy in adults with epilepsy; An alternative to vitamin D supplementation to pre
Topics: Adult; Bone Density; Bone Remodeling; Brain Ischemia; Dietary Supplements; Epilepsy; Humans; Hyperpa | 2018 |
Vitamin D status in children with epilepsy treated with levetiracetam monotherapy.
Topics: Child; Epilepsy; Humans; Levetiracetam; Piracetam; Valproic Acid; Vitamin D; Vitamin D Deficiency | 2018 |
Vitamin D supplementation and bone markers in ambulatory children on long-term valproic acid therapy. A prospective interventional study.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Biomarkers; Bone and Bones; Bone Remodeling; Chil | 2019 |
[Patent rickets disclosed by loss of convulsion control in a boy with cerebral palsy].
Topics: Anticonvulsants; Calcium; Carbamazepine; Cerebral Palsy; Child, Preschool; Diazepam; Epilepsy; Human | 2013 |
Vitamin D levels in children and adolescents with antiepileptic drug treatment.
Topics: Adolescent; Anticonvulsants; Bone Density; Bone Diseases, Metabolic; Carbamazepine; Child; Child, Pr | 2014 |
Fit for a fracture.
Topics: Anticonvulsants; Epilepsy; Ergocalciferols; Female; Femoral Neck Fractures; Follow-Up Studies; Fract | 2005 |