valproic acid has been researched along with Cystic Fibrosis of Pancreas in 5 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 years old male with myoclonic epilepsy on Valproic acid (VPA) monotherapy, developed an acute pancreatitis." | 3.77 | VPA-induced recurrent pancreatitis in a cystic fibrosis carrier. ( Alexopoulou, E; Attilakos, A; Dinopoulos, A; Fretzayas, A; Karapanou, O; Tzetis, M, 2011) |
| "Valproic acid is a first-line anti-epileptic drug and a proven HDAC inhibitor." | 2.53 | Anti-fibrotic effects of valproic acid: role of HDAC inhibition and associated mechanisms. ( Ahirwar, K; Jena, G; Khan, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barone, S | 1 |
| Cassese, E | 1 |
| Alfano, AI | 1 |
| Brindisi, M | 1 |
| Summa, V | 1 |
| Nagai, Y | 1 |
| Limberis, MP | 1 |
| Zhang, H | 1 |
| Ramachandran, S | 1 |
| Osterhaus, SR | 1 |
| Karp, PH | 1 |
| Welsh, MJ | 1 |
| McCray, PB | 1 |
| Khan, S | 1 |
| Ahirwar, K | 1 |
| Jena, G | 1 |
| Dinopoulos, A | 1 |
| Karapanou, O | 1 |
| Alexopoulou, E | 1 |
| Tzetis, M | 1 |
| Attilakos, A | 1 |
| Fretzayas, A | 1 |
2 reviews available for valproic acid and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology.
Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Histone Deacetylase 6 | 2022 |
Anti-fibrotic effects of valproic acid: role of HDAC inhibition and associated mechanisms.
Topics: Animals; Cystic Fibrosis; Epigenesis, Genetic; Fibrosis; Histone Deacetylase Inhibitors; Humans; Kid | 2016 |
3 other studies available for valproic acid and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Modulation of Treg function improves adenovirus vector-mediated gene expression in the airway.
Topics: Adaptive Immunity; Animals; Cystic Fibrosis; Dependovirus; Disease Models, Animal; Gene Transfer Tec | 2014 |
A genomic signature approach to rescue ΔF508-cystic fibrosis transmembrane conductance regulator biosynthesis and function.
Topics: Biperiden; Bronchi; Chlorides; Computational Biology; Cystic Fibrosis; Cystic Fibrosis Transmembrane | 2014 |
VPA-induced recurrent pancreatitis in a cystic fibrosis carrier.
Topics: Anticonvulsants; Child, Preschool; Cystic Fibrosis; Epilepsies, Myoclonic; Genetic Carrier Screening | 2011 |