valproic acid has been researched along with Cyclothymia in 7 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rapid cycling is a clinical subtype of bipolar mood disorder that has four or more episodes during the previous 12 months and has poor response to lithium (Li) prophylaxis treatment." | 2.40 | Algorithm for the treatment of rapid cycling. ( Yamada, K, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Carli, M | 1 |
| Weiss, F | 1 |
| Grenno, G | 1 |
| Ponzini, S | 1 |
| Kolachalam, S | 1 |
| Vaglini, F | 1 |
| Viaggi, C | 1 |
| Pardini, C | 1 |
| Tidona, S | 1 |
| Longoni, B | 1 |
| Maggio, R | 1 |
| Scarselli, M | 1 |
| Ramadas, S | 1 |
| Miklowitz, DJ | 1 |
| Chang, KD | 1 |
| Saxena, K | 1 |
| Howe, M | 1 |
| Simeonova, D | 1 |
| Steiner, H | 1 |
| Chang, K | 1 |
| Deltito, JA | 1 |
| Jacobsen, FM | 1 |
| Yamada, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Family-Focused Therapy as Early Treatment for Youth at Risk for Bipolar Disorder[NCT00943085] | 52 participants (Anticipated) | Interventional | 2007-04-30 | Completed | |||
| Early Intervention for Youth at Risk for Bipolar Disorder[NCT01483391] | 150 participants (Anticipated) | Interventional | 2011-10-06 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for valproic acid and Cyclothymia
| Article | Year |
|---|---|
Prevention of bipolar disorder in at-risk children: theoretical assumptions and empirical foundations.
Topics: Adolescent; Adult; Affect; Amygdala; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; | 2008 |
Prevention of bipolar disorder in at-risk children: theoretical assumptions and empirical foundations.
Topics: Adolescent; Adult; Affect; Amygdala; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; | 2008 |
Prevention of bipolar disorder in at-risk children: theoretical assumptions and empirical foundations.
Topics: Adolescent; Adult; Affect; Amygdala; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; | 2008 |
Prevention of bipolar disorder in at-risk children: theoretical assumptions and empirical foundations.
Topics: Adolescent; Adult; Affect; Amygdala; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; | 2008 |
Algorithm for the treatment of rapid cycling.
Topics: Algorithms; Antimanic Agents; Bipolar Disorder; Carbamazepine; Clonazepam; Cyclothymic Disorder; Dru | 1999 |
2 trials available for valproic acid and Cyclothymia
| Article | Year |
|---|---|
Divalproex sodium reduces overall aggression in youth at high risk for bipolar disorder.
Topics: Adolescent; Affect; Aggression; Antimanic Agents; Attention Deficit and Disruptive Behavior Disorder | 2006 |
Low-dose valproate: a new treatment for cyclothymia, mild rapid cycling disorders, and premenstrual syndrome.
Topics: Administration, Oral; Ambulatory Care; Bipolar Disorder; Cyclothymic Disorder; Dose-Response Relatio | 1993 |
3 other studies available for valproic acid and Cyclothymia
| Article | Year |
|---|---|
Pharmacological Strategies for Bipolar Disorders in Acute Phases and Chronic Management with a Special Focus on Lithium, Valproic Acid, and Atypical Antipsychotics.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Cyclothymic Disorder; Hum | 2023 |
A Peep Into "Peeping Tom": Successful Management of Cyclothymia Presenting as Voyeuristic Disorder.
Topics: Antimanic Agents; Cyclothymic Disorder; Disease Management; Humans; Male; Psychotherapy; Sex Offense | 2017 |
The effect of valproate on bipolar spectrum temperamental disorders.
Topics: Adult; Bipolar Disorder; Cyclothymic Disorder; Female; Humans; Male; Middle Aged; Personality Disord | 1993 |