valproic acid has been researched along with Cyanosis in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Cyanosis: A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The seizures were refractory to most anti-epileptic drugs but showed some response to Valproic acid." | 1.91 | Potassium Channel Subfamily T Member 1(KCNT1) Pathological Variant Causing Epilepsy Of Infancy With Migrating Focal Seizures: A Case Report. ( Angez, M; Chand, P; Hameed, AN; Kirmani, S, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chand, P | 1 |
| Angez, M | 1 |
| Hameed, AN | 1 |
| Kirmani, S | 1 |
| Hamed, SA | 1 |
| Elhadad, AF | 1 |
| Farghaly, HS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effectiveness of Valproic Acid in Treating Frequent Cyanotic Breath Holding Spells[NCT04482764] | Phase 1 | 150 participants (Actual) | Interventional | 2017-01-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for valproic acid and Cyanosis
| Article | Year |
|---|---|
Potassium Channel Subfamily T Member 1(KCNT1) Pathological Variant Causing Epilepsy Of Infancy With Migrating Focal Seizures: A Case Report.
Topics: Cyanosis; Epilepsy; Humans; Infant; Male; Nerve Tissue Proteins; Potassium Channels; Potassium Chann | 2023 |
Evaluation of the effectiveness of valproic acid for treating cyanotic breath holding spells: A Pilot prospective study.
Topics: Affect; Anticonvulsants; Breath Holding; Child, Preschool; Cyanosis; Electroencephalography; Female; | 2020 |