valproic acid has been researched along with Coronary Disease in 5 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gidazepam was shown to suppress the provocative arrhythmogenic effect of the stress test." | 1.28 | [Comparative anti-arrhythmia effectiveness of activators of body stress-limiting systems in patients with arrhythmia]. ( Meerson, FZ; Skibitskiĭ, VV, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meerson, FZ | 5 |
| Skibitskiĭ, VV | 2 |
| Petrova, TR | 1 |
| Pshennikova, MG | 2 |
| Shabunina, EV | 3 |
| Sazontova, TG | 1 |
| Belkina, LM | 2 |
| Malyshev, IIu | 1 |
1 trial available for valproic acid and Coronary Disease
| Article | Year |
|---|---|
[First experience in clinical trials of the new domestic drug acediprol used in the treatment of cardiac arrhythmias].
Topics: Adult; Analysis of Variance; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Double- | 1991 |
4 other studies available for valproic acid and Coronary Disease
| Article | Year |
|---|---|
[Comparative anti-arrhythmia effectiveness of activators of body stress-limiting systems in patients with arrhythmia].
Topics: Adult; Aged; Angina Pectoris; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Ben | 1992 |
[The stress-limiting systems of the body and the prevention of ventricular fibrillation].
Topics: Adaptation, Physiological; Animals; Butylated Hydroxytoluene; Coronary Disease; Male; Rats; Rats, In | 1987 |
[Prevention of arrhythmias and cardiac fibrillation in acute ischemia and reperfusion by using a factor causing GABA accumulation in the brain].
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Brain; Coronary Disease; Drug Evaluation, Preclinical; | 1987 |
[Direct cardiotropic anti-arrhythmic effect of sodium valproate].
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Drug Evaluation, Preclinical; In Vitro Techniques; | 1988 |