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valproic acid and Consciousness, Loss of

valproic acid has been researched along with Consciousness, Loss of in 13 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"Some authors suggest that most impact seizures are non-epileptic in origin and hence coined the term "concussive convulsions" for benign impact seizures."1.37[Concussive convulsions: seizure or no seizure?]. ( Burghaus, L; Elger, CE; Fink, GR; Nass, RD, 2011)
"Valproic acid-associated hyperammonemic encephalopathy (VHE) has been described in the neurology and emergency medicine literature, but the case reports identified therein are rarely derived from the psychiatric use of this medication."1.33Valproic acid-associated hyperammonemic encephalopathy: a case report from the psychiatric setting. ( Irwin, SA; Kimmel, RJ; Meyer, JM, 2005)
"We describe the case of a 26 years old woman in chronic therapy with phenobarbital, carbamazepine, valproic acid (VPA) and clonazepam who showed a hyperammonemic encephalopathy after an increase in dosage of VPA."1.28State of stupor from valproic acid during chronic treatment: case report. ( Buffa, C; Gentile, S; Ravetti, C; Sacerdote, I, 1991)
" In 8 of them, a therapeutic dosage of VPA caused modifications of the state of consciousness ranging from coma to drowsiness and stupor."1.27Hyperammonemia and valproate-induced alterations of the state of consciousness. A report of 8 cases. ( Arnetoli, G; Campostrini, R; Moroni, F; Paganini, M; Zaccara, G; Zappoli, R, 1984)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's4 (30.77)18.2507
2000's3 (23.08)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Verrotti, A1
Coppola, G1
D'Egidio, C1
Parisi, P1
Chiarelli, F1
Nass, RD1
Elger, CE1
Fink, GR1
Burghaus, L1
Kimmel, RJ1
Irwin, SA1
Meyer, JM1
Marill, KA1
Ellinor, PT1
Davis, DP1
Patel, RJ1
Warter, JM2
Marescaux, C2
Rumbach, L2
Micheletti, G2
Chabrier, G1
Koehl, C2
Imler, M1
Collard, M2
Zaccara, G1
Paganini, M1
Campostrini, R1
Arnetoli, G1
Zappoli, R1
Moroni, F1
Rohmer, F1
Kurtz, D1
Aguglia, U1
Gambardella, A1
Zappia, M1
Valentino, P1
Quattrone, A1
Lee, WL1
Yang, CC1
Deng, JF1
Chen, YF1
Lin, HD1
Wang, PH1
Sackellares, JC1
Lee, SI1
Dreifuss, FE1
Gentile, S1
Buffa, C1
Ravetti, C1
Sacerdote, I1
Jongsma, MJ1
Snijders, CJ1

Other Studies

13 other studies available for valproic acid and Consciousness, Loss of

ArticleYear
Gastaut type-idiopathic childhood occipital epilepsy and childhood absence epilepsy: a clinically significant association?
    Seizure, 2010, Volume: 19, Issue:6

    Topics: Anticonvulsants; Blindness; Child; Electroencephalography; Epilepsy; Epilepsy, Absence; Ethosuximide

2010
[Concussive convulsions: seizure or no seizure?].
    Fortschritte der Neurologie-Psychiatrie, 2011, Volume: 79, Issue:11

    Topics: Adult; Anticonvulsants; Brain; Brain Concussion; Electroencephalography; Epilepsy, Post-Traumatic; E

2011
Valproic acid-associated hyperammonemic encephalopathy: a case report from the psychiatric setting.
    International clinical psychopharmacology, 2005, Volume: 20, Issue:1

    Topics: Antimanic Agents; Bipolar Disorder; Brain Diseases; Confusion; Female; Humans; Hyperammonemia; Middl

2005
Case records of the Massachusetts General Hospital. Case 37-2005. A 35-year-old man with cardiac arrest while sleeping.
    The New England journal of medicine, 2005, Dec-08, Volume: 353, Issue:23

    Topics: Adult; Bundle-Branch Block; Death, Sudden, Cardiac; Diagnosis, Differential; Electrocardiography; Fa

2005
Noninvasive capnometry for continuous monitoring of mental status: a tale of 2 patients.
    The American journal of emergency medicine, 2006, Volume: 24, Issue:6

    Topics: Adult; Anti-Anxiety Agents; Capnography; Female; Flurazepam; Glasgow Coma Scale; Humans; Hypnotics a

2006
[Role of hyperammonemia in stuporous states induced by sodium valproate].
    Revue neurologique, 1983, Volume: 139, Issue:12

    Topics: Adult; Ammonia; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Female; Glutamine; Humans; U

1983
Hyperammonemia and valproate-induced alterations of the state of consciousness. A report of 8 cases.
    European neurology, 1984, Volume: 23, Issue:2

    Topics: Adult; Ammonia; Epilepsy; Female; Humans; Male; Unconsciousness; Valproic Acid

1984
[Stuporous states during treatment with sodium valproate. Pathogenetic hypotheses].
    Revue neurologique, 1981, Volume: 137, Issue:4

    Topics: Adult; Aged; Anticonvulsants; Drug Synergism; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle

1981
Negative myoclonus during valproate-related stupor. Neurophysiological evidence of a cortical non-epileptic origin.
    Electroencephalography and clinical neurophysiology, 1995, Volume: 94, Issue:2

    Topics: Adult; Age of Onset; Cerebral Cortex; Electroencephalography; Epilepsies, Partial; Epilepsy; Female;

1995
A case of severe hyperammonemia and unconsciousness following sodium valproate intoxication.
    Veterinary and human toxicology, 1998, Volume: 40, Issue:6

    Topics: Adolescent; Ammonia; Anion Exchange Resins; Anticonvulsants; Cholestyramine Resin; Drug Overdose; Hu

1998
Stupor following administration of valproic acid to patients receiving other antiepileptic drugs.
    Epilepsia, 1979, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography; Epilep

1979
State of stupor from valproic acid during chronic treatment: case report.
    Italian journal of neurological sciences, 1991, Volume: 12, Issue:2

    Topics: Adult; Brain Diseases; Carbamazepine; Clonazepam; Electroencephalography; Epilepsies, Myoclonic; Fem

1991
[Valproic acid and stupor].
    Nederlands tijdschrift voor geneeskunde, 1990, Oct-27, Volume: 134, Issue:43

    Topics: Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Male; Middle Aged; Phenytoin; Unconsciou

1990